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The Trp64Arg polymorphism of the beta 3-adrenergic receptor gene is not associated with obesity or type 2 diabetes mellitus in a large population-based Caucasian cohort.
Büettner R, Schäffler A, Arndt H, Rogler G, Nusser J, Zietz B, Enger I, Hügl S, Cuk A, Schölmerich J, Palitzsch KD. Büettner R, et al. Among authors: schaffler a. J Clin Endocrinol Metab. 1998 Aug;83(8):2892-7. doi: 10.1210/jcem.83.8.5004. J Clin Endocrinol Metab. 1998. PMID: 9709965
The human apM-1, an adipocyte-specific gene linked to the family of TNF's and to genes expressed in activated T cells, is mapped to chromosome 1q21.3-q23, a susceptibility locus identified for familial combined hyperlipidaemia (FCH).
Schäffler A, Orsó E, Palitzsch KD, Büchler C, Drobnik W, Fürst A, Schölmerich J, Schmitz G. Schäffler A, et al. Biochem Biophys Res Commun. 1999 Jul 5;260(2):416-25. doi: 10.1006/bbrc.1999.0865. Biochem Biophys Res Commun. 1999. PMID: 10403784
Frequency and significance of the A-->G (-3826) polymorphism in the promoter of the gene for uncoupling protein-1 with regard to metabolic parameters and adipocyte transcription factor binding in a large population-based Caucasian cohort.
Schäffler A, Palitzsch KD, Watzlawek E, Drobnik W, Schwer H, Schölmerich J, Schmitz G. Schäffler A, et al. Eur J Clin Invest. 1999 Sep;29(9):770-9. doi: 10.1046/j.1365-2362.1999.00529.x. Eur J Clin Invest. 1999. PMID: 10469165
Identification of a new missense mutation (Gly95Glu) in a highly conserved codon within the high-mobility group box of the sex-determining region Y gene: report on a 46,XY female with gonadal dysgenesis and yolk-sac tumor.
Schäffler A, Barth N, Winkler K, Zietz B, Rümmele P, Knüchel R, Schölmerich J, Palitzsch KD. Schäffler A, et al. J Clin Endocrinol Metab. 2000 Jun;85(6):2287-92. doi: 10.1210/jcem.85.6.6637. J Clin Endocrinol Metab. 2000. PMID: 10852465
Amelioration of hyperglycemic and hyperosmotic induced vascular dysfunction by in vivo inhibition of protein kinase C and p38 MAP kinase pathway in the rat mesenteric microcirculation.
Schäffler A, Arndt H, Schölmerich J, Palitzsch KD. Schäffler A, et al. Eur J Clin Invest. 2000 Jul;30(7):586-93. doi: 10.1046/j.1365-2362.2000.00680.x. Eur J Clin Invest. 2000. PMID: 10886298
RESULTS: Acutely induced hyperglycemia resulted in a significant increase in leukocyte adhesion. This effect could be mimicked by mannitol. ...CONCLUSION: The observed effects of glucose on adhesion, emigration and shear rate are due to osmotic effects. The PKC/MAP kinase …
RESULTS: Acutely induced hyperglycemia resulted in a significant increase in leukocyte adhesion. This effect could be mimicked by man …
206 results