Schönherr C - Search Results

1

Activating ALK mutations found in neuroblastoma are inhibited by Crizotinib and NVP-TAE684.

Schönherr C, Ruuth K, Yamazaki Y, Eriksson T, Christensen J, Palmer RH, Hallberg B. Schönherr C, et al. Biochem J. 2011 Dec 15;440(3):405-13. doi: 10.1042/BJ20101796. Biochem J. 2011. PMID: 21838707

2

Goliath family E3 ligases regulate the recycling endosome pathway via VAMP3 ubiquitylation.

Yamazaki Y, Schönherr C, Varshney GK, Dogru M, Hallberg B, Palmer RH. Yamazaki Y, et al. Among authors: schonherr c. EMBO J. 2013 Feb 20;32(4):524-37. doi: 10.1038/emboj.2013.1. Epub 2013 Jan 25. EMBO J. 2013. PMID: 23353890 Free PMC article.

3

Jeb/Alk signalling regulates the Lame duck GLI family transcription factor in the Drosophila visceral mesoderm.

Popichenko D, Hugosson F, Sjögren C, Dogru M, Yamazaki Y, Wolfstetter G, Schönherr C, Fallah M, Hallberg B, Nguyen H, Palmer RH. Popichenko D, et al. Among authors: schonherr c. Development. 2013 Aug;140(15):3156-66. doi: 10.1242/dev.094466. Epub 2013 Jul 3. Development. 2013. PMID: 23824577

4

The kinase ALK stimulates the kinase ERK5 to promote the expression of the oncogene MYCN in neuroblastoma.

Umapathy G, El Wakil A, Witek B, Chesler L, Danielson L, Deng X, Gray NS, Johansson M, Kvarnbrink S, Ruuth K, Schönherr C, Palmer RH, Hallberg B. Umapathy G, et al. Among authors: schonherr c. Sci Signal. 2014 Oct 28;7(349):ra102. doi: 10.1126/scisignal.2005470. Sci Signal. 2014. PMID: 25351247

5

Phosphoproteomic analysis of anaplastic lymphoma kinase (ALK) downstream signaling pathways identifies signal transducer and activator of transcription 3 as a functional target of activated ALK in neuroblastoma cells.

Sattu K, Hochgräfe F, Wu J, Umapathy G, Schönherr C, Ruuth K, Chand D, Witek B, Fuchs J, Li PK, Hugosson F, Daly RJ, Palmer RH, Hallberg B. Sattu K, et al. Among authors: schonherr c. FEBS J. 2013 Nov;280(21):5269-82. doi: 10.1111/febs.12453. Epub 2013 Aug 22. FEBS J. 2013. PMID: 23889739 Free PMC article.

6

Cell culture and Drosophila model systems define three classes of anaplastic lymphoma kinase mutations in neuroblastoma.

Chand D, Yamazaki Y, Ruuth K, Schönherr C, Martinsson T, Kogner P, Attiyeh EF, Maris J, Morozova O, Marra MA, Ohira M, Nakagawara A, Sandström PE, Palmer RH, Hallberg B. Chand D, et al. Among authors: schonherr c. Dis Model Mech. 2013 Mar;6(2):373-82. doi: 10.1242/dmm.010348. Epub 2012 Oct 25. Dis Model Mech. 2013. PMID: 23104988 Free PMC article.

7

Anaplastic lymphoma kinase in human cancer.

Schonherr C, Hallberg B, Palmer R. Schonherr C, et al. Crit Rev Oncog. 2012;17(2):123-43. doi: 10.1615/critrevoncog.v17.i2.10. Crit Rev Oncog. 2012. PMID: 22471704 Review.

8

Appearance of the novel activating F1174S ALK mutation in neuroblastoma correlates with aggressive tumor progression and unresponsiveness to therapy.

Martinsson T, Eriksson T, Abrahamsson J, Caren H, Hansson M, Kogner P, Kamaraj S, Schönherr C, Weinmar J, Ruuth K, Palmer RH, Hallberg B. Martinsson T, et al. Among authors: schonherr c. Cancer Res. 2011 Jan 1;71(1):98-105. doi: 10.1158/0008-5472.CAN-10-2366. Epub 2010 Nov 8. Cancer Res. 2011. PMID: 21059859

9

The neuroblastoma ALK(I1250T) mutation is a kinase-dead RTK in vitro and in vivo.

Schönherr C, Ruuth K, Eriksson T, Yamazaki Y, Ottmann C, Combaret V, Vigny M, Kamaraj S, Palmer RH, Hallberg B. Schönherr C, et al. Transl Oncol. 2011 Aug;4(4):258-65. doi: 10.1593/tlo.11139. Epub 2011 Aug 1. Transl Oncol. 2011. PMID: 21804922 Free PMC article.

10

Anaplastic lymphoma kinase activates the small GTPase Rap1 via the Rap1-specific GEF C3G in both neuroblastoma and PC12 cells.

Schönherr C, Yang HL, Vigny M, Palmer RH, Hallberg B. Schönherr C, et al. Oncogene. 2010 May 13;29(19):2817-30. doi: 10.1038/onc.2010.27. Epub 2010 Mar 1. Oncogene. 2010. PMID: 20190816

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