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17 results
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Co-crystallization with conformation-specific designed ankyrin repeat proteins explains the conformational flexibility of BCL-W.
Schilling J, Schöppe J, Sauer E, Plückthun A. Schilling J, et al. Among authors: schoppe j. J Mol Biol. 2014 Jun 12;426(12):2346-62. doi: 10.1016/j.jmb.2014.04.010. Epub 2014 Apr 18. J Mol Biol. 2014. PMID: 24747052
From DARPins to LoopDARPins: novel LoopDARPin design allows the selection of low picomolar binders in a single round of ribosome display.
Schilling J, Schöppe J, Plückthun A. Schilling J, et al. Among authors: schoppe j. J Mol Biol. 2014 Feb 6;426(3):691-721. doi: 10.1016/j.jmb.2013.10.026. J Mol Biol. 2014. PMID: 24513107
Phase behavior of a designed cyclopropyl analogue of monoolein: implications for low-temperature membrane protein crystallization.
Salvati Manni L, Zabara A, Osornio YM, Schöppe J, Batyuk A, Plückthun A, Siegel JS, Mezzenga R, Landau EM. Salvati Manni L, et al. Among authors: schoppe j. Angew Chem Int Ed Engl. 2015 Jan 12;54(3):1027-31. doi: 10.1002/anie.201409791. Epub 2014 Nov 21. Angew Chem Int Ed Engl. 2015. PMID: 25418121
Comprehensive analysis of heterotrimeric G-protein complex diversity and their interactions with GPCRs in solution.
Hillenbrand M, Schori C, Schöppe J, Plückthun A. Hillenbrand M, et al. Among authors: schoppe j. Proc Natl Acad Sci U S A. 2015 Mar 17;112(11):E1181-90. doi: 10.1073/pnas.1417573112. Epub 2015 Mar 2. Proc Natl Acad Sci U S A. 2015. PMID: 25733868 Free PMC article.
Generation of Fluorogen-Activating Designed Ankyrin Repeat Proteins (FADAs) as Versatile Sensor Tools.
Schütz M, Batyuk A, Klenk C, Kummer L, de Picciotto S, Gülbakan B, Wu Y, Newby GA, Zosel F, Schöppe J, Sedlák E, Mittl PRE, Zenobi R, Wittrup KD, Plückthun A. Schütz M, et al. Among authors: schoppe j. J Mol Biol. 2016 Mar 27;428(6):1272-1289. doi: 10.1016/j.jmb.2016.01.017. Epub 2016 Jan 23. J Mol Biol. 2016. PMID: 26812208
High-resolution crystal structure of parathyroid hormone 1 receptor in complex with a peptide agonist.
Ehrenmann J, Schöppe J, Klenk C, Rappas M, Kummer L, Doré AS, Plückthun A. Ehrenmann J, et al. Among authors: schoppe j. Nat Struct Mol Biol. 2018 Dec;25(12):1086-1092. doi: 10.1038/s41594-018-0151-4. Epub 2018 Nov 19. Nat Struct Mol Biol. 2018. PMID: 30455434
Crystal structures of the human neurokinin 1 receptor in complex with clinically used antagonists.
Schöppe J, Ehrenmann J, Klenk C, Rucktooa P, Schütz M, Doré AS, Plückthun A. Schöppe J, et al. Nat Commun. 2019 Jan 3;10(1):17. doi: 10.1038/s41467-018-07939-8. Nat Commun. 2019. PMID: 30604743 Free PMC article.
New views into class B GPCRs from the crystal structure of PTH1R.
Ehrenmann J, Schöppe J, Klenk C, Plückthun A. Ehrenmann J, et al. Among authors: schoppe j. FEBS J. 2019 Dec;286(24):4852-4860. doi: 10.1111/febs.15115. Epub 2019 Nov 18. FEBS J. 2019. PMID: 31670461 Free article. Review.
Crystal structure of the human oxytocin receptor.
Waltenspühl Y, Schöppe J, Ehrenmann J, Kummer L, Plückthun A. Waltenspühl Y, et al. Among authors: schoppe j. Sci Adv. 2020 Jul 15;6(29):eabb5419. doi: 10.1126/sciadv.abb5419. eCollection 2020 Jul. Sci Adv. 2020. PMID: 32832646 Free PMC article.
Structural basis for allosteric cross-talk between the asymmetric nucleotide binding sites of a heterodimeric ABC exporter.
Hohl M, Hürlimann LM, Böhm S, Schöppe J, Grütter MG, Bordignon E, Seeger MA. Hohl M, et al. Among authors: schoppe j. Proc Natl Acad Sci U S A. 2014 Jul 29;111(30):11025-30. doi: 10.1073/pnas.1400485111. Epub 2014 Jul 16. Proc Natl Acad Sci U S A. 2014. PMID: 25030449 Free PMC article.
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