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Use of synthetic oligosaccharide substrate analogs to map the active sites of N-acetylglucosaminyltransferases I and II.
Schachter H, Reck F, Paulsen H. Schachter H, et al. Methods Enzymol. 2003;363:459-75. doi: 10.1016/S0076-6879(03)01072-3. Methods Enzymol. 2003. PMID: 14579596
The directed migration of gonadal distal tip cells in Caenorhabditis elegans requires NGAT-1, a ß1,4-N-acetylgalactosaminyltransferase enzyme.
Veyhl J, Dunn RJ, Johnston WL, Bennett A, Zhang LW, Dennis JW, Schachter H, Culotti JG. Veyhl J, et al. Among authors: schachter h. PLoS One. 2017 Aug 17;12(8):e0183049. doi: 10.1371/journal.pone.0183049. eCollection 2017. PLoS One. 2017. PMID: 28817611 Free PMC article.
Functional post-translational proteomics approach to study the role of N-glycans in the development of Caenorhabditis elegans.
Schachter H, Chen S, Zhang W, Spence AM, Zhu S, Callahan JW, Mahuran DJ, Fan X, Bagshaw RD, She YM, Rosa JC, Reinhold VN. Schachter H, et al. Biochem Soc Symp. 2002;(69):1-21. doi: 10.1042/bss0690001. Biochem Soc Symp. 2002. PMID: 12655770 Review.
Caenorhabditis elegans triple null mutant lacking UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.
Zhu S, Hanneman A, Reinhold VN, Spence AM, Schachter H. Zhu S, et al. Among authors: schachter h. Biochem J. 2004 Sep 15;382(Pt 3):995-1001. doi: 10.1042/BJ20040793. Biochem J. 2004. PMID: 15228383 Free PMC article.
Synthesis of paucimannose N-glycans by Caenorhabditis elegans requires prior actions of UDP-N-acetyl-D-glucosamine:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I, alpha3,6-mannosidase II and a specific membrane-bound beta-N-acetylglucosaminidase.
Zhang W, Cao P, Chen S, Spence AM, Zhu S, Staudacher E, Schachter H. Zhang W, et al. Among authors: schachter h. Biochem J. 2003 May 15;372(Pt 1):53-64. doi: 10.1042/BJ20021931. Biochem J. 2003. PMID: 12603202 Free PMC article.
Cloning and expression of a novel UDP-GlcNAc:alpha-D-mannoside beta1,2-N-acetylglucosaminyltransferase homologous to UDP-GlcNAc:alpha-3-D-mannoside beta1,2-N-acetylglucosaminyltransferase I.
Zhang W, Betel D, Schachter H. Zhang W, et al. Among authors: schachter h. Biochem J. 2002 Jan 1;361(Pt 1):153-62. doi: 10.1042/0264-6021:3610153. Biochem J. 2002. PMID: 11742540 Free PMC article.
UDP-N-acetylglucosamine:alpha-3-D-mannoside beta-1,2-N-acetylglucosaminyltransferase I and UDP-N-acetylglucosamine:alpha-6-D-mannoside beta-1,2-N-acetylglucosaminyltransferase II in Caenorhabditis elegans.
Chen S, Tan J, Reinhold VN, Spence AM, Schachter H. Chen S, et al. Among authors: schachter h. Biochim Biophys Acta. 2002 Dec 19;1573(3):271-9. doi: 10.1016/s0304-4165(02)00393-8. Biochim Biophys Acta. 2002. PMID: 12417409 Review.
Neuronal expression of Mgat1 rescues the shortened life span of Drosophila Mgat11 null mutants and increases life span.
Sarkar M, Iliadi KG, Leventis PA, Schachter H, Boulianne GL. Sarkar M, et al. Among authors: schachter h. Proc Natl Acad Sci U S A. 2010 May 25;107(21):9677-82. doi: 10.1073/pnas.1004431107. Epub 2010 May 10. Proc Natl Acad Sci U S A. 2010. PMID: 20457894 Free PMC article.
Null mutations in Drosophila N-acetylglucosaminyltransferase I produce defects in locomotion and a reduced life span.
Sarkar M, Leventis PA, Silvescu CI, Reinhold VN, Schachter H, Boulianne GL. Sarkar M, et al. Among authors: schachter h. J Biol Chem. 2006 May 5;281(18):12776-85. doi: 10.1074/jbc.M512769200. Epub 2006 Mar 7. J Biol Chem. 2006. PMID: 16522637
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