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Persistent HIV-1 replication is associated with lower antiretroviral drug concentrations in lymphatic tissues.
Fletcher CV, Staskus K, Wietgrefe SW, Rothenberger M, Reilly C, Chipman JG, Beilman GJ, Khoruts A, Thorkelson A, Schmidt TE, Anderson J, Perkey K, Stevenson M, Perelson AS, Douek DC, Haase AT, Schacker TW. Fletcher CV, et al. Among authors: schacker tw. Proc Natl Acad Sci U S A. 2014 Feb 11;111(6):2307-12. doi: 10.1073/pnas.1318249111. Epub 2014 Jan 27. Proc Natl Acad Sci U S A. 2014. PMID: 24469825 Free PMC article.
Inguinal lymph node and anorectal mucosal biopsies for human immunodeficiency virus research protocols in an emerging nation: patient outcomes and lessons learned.
Rothenberger MK, Mutuluuza CK, Ssali F, Jasurda J, Schmidt T, Schacker TW, Beilman GJ, Chipman JG. Rothenberger MK, et al. Among authors: schacker tw. Surg Infect (Larchmt). 2015 Feb;16(1):68-71. doi: 10.1089/sur.2013.179. Epub 2015 Feb 4. Surg Infect (Larchmt). 2015. PMID: 25650809 Free PMC article.
Large number of rebounding/founder HIV variants emerge from multifocal infection in lymphatic tissues after treatment interruption.
Rothenberger MK, Keele BF, Wietgrefe SW, Fletcher CV, Beilman GJ, Chipman JG, Khoruts A, Estes JD, Anderson J, Callisto SP, Schmidt TE, Thorkelson A, Reilly C, Perkey K, Reimann TG, Utay NS, Nganou Makamdop K, Stevenson M, Douek DC, Haase AT, Schacker TW. Rothenberger MK, et al. Among authors: schacker tw. Proc Natl Acad Sci U S A. 2015 Mar 10;112(10):E1126-34. doi: 10.1073/pnas.1414926112. Epub 2015 Feb 23. Proc Natl Acad Sci U S A. 2015. PMID: 25713386 Free PMC article.
Persistent HIV-1 replication maintains the tissue reservoir during therapy.
Lorenzo-Redondo R, Fryer HR, Bedford T, Kim EY, Archer J, Pond SLK, Chung YS, Penugonda S, Chipman J, Fletcher CV, Schacker TW, Malim MH, Rambaut A, Haase AT, McLean AR, Wolinsky SM. Lorenzo-Redondo R, et al. Among authors: schacker tw. Nature. 2016 Feb 4;530(7588):51-56. doi: 10.1038/nature16933. Epub 2016 Jan 27. Nature. 2016. PMID: 26814962 Free PMC article.
Defining total-body AIDS-virus burden with implications for curative strategies.
Estes JD, Kityo C, Ssali F, Swainson L, Makamdop KN, Del Prete GQ, Deeks SG, Luciw PA, Chipman JG, Beilman GJ, Hoskuldsson T, Khoruts A, Anderson J, Deleage C, Jasurda J, Schmidt TE, Hafertepe M, Callisto SP, Pearson H, Reimann T, Schuster J, Schoephoerster J, Southern P, Perkey K, Shang L, Wietgrefe SW, Fletcher CV, Lifson JD, Douek DC, McCune JM, Haase AT, Schacker TW. Estes JD, et al. Among authors: schacker tw. Nat Med. 2017 Nov;23(11):1271-1276. doi: 10.1038/nm.4411. Epub 2017 Oct 2. Nat Med. 2017. PMID: 28967921 Free PMC article.
145 results