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Treatment of vitiligo with a topical application of pseudocatalase and calcium in combination with short-term UVB exposure: a case study on 33 patients.
Schallreuter KU, Wood JM, Lemke KR, Levenig C. Schallreuter KU, et al. Dermatology. 1995;190(3):223-9. doi: 10.1159/000246690. Dermatology. 1995. PMID: 7599386
In vivo and in vitro evidence for epidermal H2O2-mediated oxidative stress in piebaldism.
Vafaee T, Rokos H, Salem MM, Schallreuter KU. Vafaee T, et al. Among authors: schallreuter ku. Exp Dermatol. 2010 Oct;19(10):883-7. doi: 10.1111/j.1600-0625.2009.00966.x. Exp Dermatol. 2010. PMID: 19758321
Basic evidence for epidermal H2O2/ONOO(-)-mediated oxidation/nitration in segmental vitiligo is supported by repigmentation of skin and eyelashes after reduction of epidermal H2O2 with topical NB-UVB-activated pseudocatalase PC-KUS.
Schallreuter KU, Salem MA, Holtz S, Panske A. Schallreuter KU, et al. FASEB J. 2013 Aug;27(8):3113-22. doi: 10.1096/fj.12-226779. Epub 2013 Apr 29. FASEB J. 2013. PMID: 23629861
Basic research confirms coexistence of acquired Blaschkolinear Vitiligo and acrofacial Vitiligo.
Schallreuter KU, Krüger C, Rokos H, Hasse S, Zothner C, Panske A. Schallreuter KU, et al. Arch Dermatol Res. 2007 Aug;299(5-6):225-30. doi: 10.1007/s00403-007-0748-7. Epub 2007 Apr 3. Arch Dermatol Res. 2007. PMID: 17404749
Perturbed 6-tetrahydrobiopterin recycling via decreased dihydropteridine reductase in vitiligo: more evidence for H2O2 stress.
Hasse S, Gibbons NC, Rokos H, Marles LK, Schallreuter KU. Hasse S, et al. Among authors: schallreuter ku. J Invest Dermatol. 2004 Feb;122(2):307-13. doi: 10.1046/j.0022-202X.2004.22230.x. J Invest Dermatol. 2004. PMID: 15009710
Activation/deactivation of acetylcholinesterase by H2O2: more evidence for oxidative stress in vitiligo.
Schallreuter KU, Elwary SM, Gibbons NC, Rokos H, Wood JM. Schallreuter KU, et al. Biochem Biophys Res Commun. 2004 Mar 5;315(2):502-8. doi: 10.1016/j.bbrc.2004.01.082. Biochem Biophys Res Commun. 2004. PMID: 14766237
Oxidative stress in vitiligo: photo-oxidation of pterins produces H(2)O(2) and pterin-6-carboxylic acid.
Rokos H, Beazley WD, Schallreuter KU. Rokos H, et al. Among authors: schallreuter ku. Biochem Biophys Res Commun. 2002 Apr 12;292(4):805-11. doi: 10.1006/bbrc.2002.6727. Biochem Biophys Res Commun. 2002. PMID: 11944885 Clinical Trial.
Decreased photodamage and low incidence of non-melanoma skin cancer in 136 sun-exposed caucasian patients with vitiligo.
Schallreuter KU, Tobin DJ, Panske A. Schallreuter KU, et al. Dermatology. 2002;204(3):194-201. doi: 10.1159/000057881. Dermatology. 2002. PMID: 12037447
Computer simulation of heterogeneous single nucleotide polymorphisms in the catalase gene indicates structural changes in the enzyme active site, NADPH-binding and tetramerization domains: a genetic predisposition for an altered catalase in patients with vitiligo?
Wood JM, Gibbons NC, Chavan B, Schallreuter KU. Wood JM, et al. Among authors: schallreuter ku. Exp Dermatol. 2008 Apr;17(4):366-71. doi: 10.1111/j.1600-0625.2008.00699.x. Exp Dermatol. 2008. PMID: 18315617
Methionine sulfoxide reductases A and B are deactivated by hydrogen peroxide (H2O2) in the epidermis of patients with vitiligo.
Schallreuter KU, Rübsam K, Gibbons NC, Maitland DJ, Chavan B, Zothner C, Rokos H, Wood JM. Schallreuter KU, et al. J Invest Dermatol. 2008 Apr;128(4):808-15. doi: 10.1038/sj.jid.5701100. Epub 2007 Oct 18. J Invest Dermatol. 2008. PMID: 17943184
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