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Mast Cell and Eosinophil Activation Are Associated With COVID-19 and TLR-Mediated Viral Inflammation: Implications for an Anti-Siglec-8 Antibody.
Gebremeskel S, Schanin J, Coyle KM, Butuci M, Luu T, Brock EC, Xu A, Wong A, Leung J, Korver W, Morin RD, Schleimer RP, Bochner BS, Youngblood BA. Gebremeskel S, et al. Among authors: schanin j. Front Immunol. 2021 Mar 10;12:650331. doi: 10.3389/fimmu.2021.650331. eCollection 2021. Front Immunol. 2021. PMID: 33777047 Free PMC article.
A monoclonal antibody to Siglec-8 suppresses non-allergic airway inflammation and inhibits IgE-independent mast cell activation.
Schanin J, Gebremeskel S, Korver W, Falahati R, Butuci M, Haw TJ, Nair PM, Liu G, Hansbro NG, Hansbro PM, Evensen E, Brock EC, Xu A, Wong A, Leung J, Bebbington C, Tomasevic N, Youngblood BA. Schanin J, et al. Mucosal Immunol. 2021 Mar;14(2):366-376. doi: 10.1038/s41385-020-00336-9. Epub 2020 Aug 19. Mucosal Immunol. 2021. PMID: 32814824 Free PMC article.
Discovery, Function, and Therapeutic Targeting of Siglec-8.
Youngblood BA, Leung J, Falahati R, Williams J, Schanin J, Brock EC, Singh B, Chang AT, O'Sullivan JA, Schleimer RP, Tomasevic N, Bebbington CR, Bochner BS. Youngblood BA, et al. Among authors: schanin j. Cells. 2020 Dec 24;10(1):19. doi: 10.3390/cells10010019. Cells. 2020. PMID: 33374255 Free PMC article. Review.
Functional and Phenotypic Characterization of Siglec-6 on Human Mast Cells.
Robida PA, Rische CH, Morgenstern NB, Janarthanam R, Cao Y, Krier-Burris RA, Korver W, Xu A, Luu T, Schanin J, Leung J, Rothenberg ME, Wechsler JB, Youngblood BA, Bochner BS, O'Sullivan JA. Robida PA, et al. Among authors: schanin j. Cells. 2022 Mar 28;11(7):1138. doi: 10.3390/cells11071138. Cells. 2022. PMID: 35406705 Free PMC article.
A DLG1-ARHGAP31-CDC42 axis is essential for the intestinal stem cell response to fluctuating niche Wnt signaling.
Castillo-Azofeifa D, Wald T, Reyes EA, Gallagher A, Schanin J, Vlachos S, Lamarche-Vane N, Bomidi C, Blutt S, Estes MK, Nystul T, Klein OD. Castillo-Azofeifa D, et al. Among authors: schanin j. Cell Stem Cell. 2023 Feb 2;30(2):188-206.e6. doi: 10.1016/j.stem.2022.12.008. Epub 2023 Jan 13. Cell Stem Cell. 2023. PMID: 36640764 Free PMC article.