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Imaging of Human Insulin Secreting Cells with Gd-DOTA-P88, a Paramagnetic Contrast Agent Targeting the Beta Cell Biomarker FXYD2γa.
Demine S, Balhuizen A, Debaille V, Joosten L, Fereau M, Chilla SNM, Millard I, Scharfmann R, Egrise D, Goldman S, Marchetti P, Gotthardt M, Laurent S, Burtea C, Eizirik DL. Demine S, et al. Among authors: scharfmann r. Molecules. 2018 Aug 21;23(9):2100. doi: 10.3390/molecules23092100. Molecules. 2018. PMID: 30134599 Free PMC article.
Expression and functional assessment of candidate type 2 diabetes susceptibility genes identify four new genes contributing to human insulin secretion.
Ndiaye FK, Ortalli A, Canouil M, Huyvaert M, Salazar-Cardozo C, Lecoeur C, Verbanck M, Pawlowski V, Boutry R, Durand E, Rabearivelo I, Sand O, Marselli L, Kerr-Conte J, Chandra V, Scharfmann R, Poulain-Godefroy O, Marchetti P, Pattou F, Abderrahmani A, Froguel P, Bonnefond A. Ndiaye FK, et al. Among authors: scharfmann r. Mol Metab. 2017 Apr 8;6(6):459-470. doi: 10.1016/j.molmet.2017.03.011. eCollection 2017 Jun. Mol Metab. 2017. PMID: 28580277 Free PMC article.
A nanobody-based tracer targeting DPP6 for non-invasive imaging of human pancreatic endocrine cells.
Balhuizen A, Massa S, Mathijs I, Turatsinze JV, De Vos J, Demine S, Xavier C, Villate O, Millard I, Egrise D, Capito C, Scharfmann R, In't Veld P, Marchetti P, Muyldermans S, Goldman S, Lahoutte T, Bouwens L, Eizirik DL, Devoogdt N. Balhuizen A, et al. Among authors: scharfmann r. Sci Rep. 2017 Nov 9;7(1):15130. doi: 10.1038/s41598-017-15417-2. Sci Rep. 2017. PMID: 29123178 Free PMC article.
Virus-like infection induces human β cell dedifferentiation.
Oshima M, Knoch KP, Diedisheim M, Petzold A, Cattan P, Bugliani M, Marchetti P, Choudhary P, Huang GC, Bornstein SR, Solimena M, Albagli-Curiel O, Scharfmann R. Oshima M, et al. Among authors: scharfmann r. JCI Insight. 2018 Feb 8;3(3):e97732. doi: 10.1172/jci.insight.97732. eCollection 2018 Feb 8. JCI Insight. 2018. PMID: 29415896 Free PMC article.
Modeling human pancreatic beta cell dedifferentiation.
Diedisheim M, Oshima M, Albagli O, Huldt CW, Ahlstedt I, Clausen M, Menon S, Aivazidis A, Andreasson AC, Haynes WG, Marchetti P, Marselli L, Armanet M, Chimienti F, Scharfmann R. Diedisheim M, et al. Among authors: scharfmann r. Mol Metab. 2018 Apr;10:74-86. doi: 10.1016/j.molmet.2018.02.002. Epub 2018 Feb 8. Mol Metab. 2018. PMID: 29472102 Free PMC article.
Conventional and Neo-antigenic Peptides Presented by β Cells Are Targeted by Circulating Naïve CD8+ T Cells in Type 1 Diabetic and Healthy Donors.
Gonzalez-Duque S, Azoury ME, Colli ML, Afonso G, Turatsinze JV, Nigi L, Lalanne AI, Sebastiani G, Carré A, Pinto S, Culina S, Corcos N, Bugliani M, Marchetti P, Armanet M, Diedisheim M, Kyewski B, Steinmetz LM, Buus S, You S, Dubois-Laforgue D, Larger E, Beressi JP, Bruno G, Dotta F, Scharfmann R, Eizirik DL, Verdier Y, Vinh J, Mallone R. Gonzalez-Duque S, et al. Among authors: scharfmann r. Cell Metab. 2018 Dec 4;28(6):946-960.e6. doi: 10.1016/j.cmet.2018.07.007. Epub 2018 Aug 2. Cell Metab. 2018. PMID: 30078552 Free article.
Fostering improved human islet research: a European perspective.
Marchetti P, Schulte AM, Marselli L, Schoniger E, Bugliani M, Kramer W, Overbergh L, Ullrich S, Gloyn AL, Ibberson M, Rutter G, Froguel P, Groop L, McCarthy MI, Dotta F, Scharfmann R, Magnan C, Eizirik DL, Mathieu C, Cnop M, Thorens B, Solimena M. Marchetti P, et al. Among authors: scharfmann r. Diabetologia. 2019 Aug;62(8):1514-1516. doi: 10.1007/s00125-019-4911-4. Epub 2019 Jun 13. Diabetologia. 2019. PMID: 31197398 Free PMC article. No abstract available.
Stearoyl CoA desaturase is a gatekeeper that protects human beta cells against lipotoxicity and maintains their identity.
Oshima M, Pechberty S, Bellini L, Göpel SO, Campana M, Rouch C, Dairou J, Cosentino C, Fantuzzi F, Toivonen S, Marchetti P, Magnan C, Cnop M, Le Stunff H, Scharfmann R. Oshima M, et al. Among authors: scharfmann r. Diabetologia. 2020 Feb;63(2):395-409. doi: 10.1007/s00125-019-05046-x. Epub 2019 Dec 3. Diabetologia. 2020. PMID: 31796987 Free PMC article.
EndoC-βH5 cells are storable and ready-to-use human pancreatic beta cells with physiological insulin secretion.
Blanchi B, Taurand M, Colace C, Thomaidou S, Audeoud C, Fantuzzi F, Sawatani T, Gheibi S, Sabadell-Basallote J, Boot FWJ, Chantier T, Piet A, Cavanihac C, Pilette M, Balguerie A, Olleik H, Carlotti F, Ejarque M, Fex M, Mulder H, Cnop M, Eizirik DL, Jouannot O, Gaffuri AL, Czernichow P, Zaldumbide A, Scharfmann R, Ravassard P. Blanchi B, et al. Among authors: scharfmann r. Mol Metab. 2023 Oct;76:101772. doi: 10.1016/j.molmet.2023.101772. Epub 2023 Jul 11. Mol Metab. 2023. PMID: 37442376 Free PMC article.
194 results