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Xenobiotic receptor humanized mice and their utility.
Scheer N, Roland Wolf C. Scheer N, et al. Drug Metab Rev. 2013 Feb;45(1):110-21. doi: 10.3109/03602532.2012.738687. Epub 2012 Nov 23. Drug Metab Rev. 2013. PMID: 23173549 Review.
Humanized UGT2 and CYP3A transchromosomic rats for improved prediction of human drug metabolism.
Kazuki Y, Kobayashi K, Hirabayashi M, Abe S, Kajitani N, Kazuki K, Takehara S, Takiguchi M, Satoh D, Kuze J, Sakuma T, Kaneko T, Mashimo T, Osamura M, Hashimoto M, Wakatsuki R, Hirashima R, Fujiwara R, Deguchi T, Kurihara A, Tsukazaki Y, Senda N, Yamamoto T, Scheer N, Oshimura M. Kazuki Y, et al. Among authors: scheer n. Proc Natl Acad Sci U S A. 2019 Feb 19;116(8):3072-3081. doi: 10.1073/pnas.1808255116. Epub 2019 Feb 4. Proc Natl Acad Sci U S A. 2019. PMID: 30718425 Free PMC article.
Generation and Characterization of a Breast Cancer Resistance Protein Humanized Mouse Model.
Dallas S, Salphati L, Gomez-Zepeda D, Wanek T, Chen L, Chu X, Kunta J, Mezler M, Menet MC, Chasseigneaux S, Declèves X, Langer O, Pierre E, DiLoreto K, Hoft C, Laplanche L, Pang J, Pereira T, Andonian C, Simic D, Rode A, Yabut J, Zhang X, Scheer N. Dallas S, et al. Among authors: scheer n. Mol Pharmacol. 2016 May;89(5):492-504. doi: 10.1124/mol.115.102079. Epub 2016 Feb 18. Mol Pharmacol. 2016. PMID: 26893303
Phenobarbital induces cell cycle transcriptional responses in mouse liver humanized for constitutive androstane and pregnane x receptors.
Luisier R, Lempiäinen H, Scherbichler N, Braeuning A, Geissler M, Dubost V, Müller A, Scheer N, Chibout SD, Hara H, Picard F, Theil D, Couttet P, Vitobello A, Grenet O, Grasl-Kraupp B, Ellinger-Ziegelbauer H, Thomson JP, Meehan RR, Elcombe CR, Henderson CJ, Wolf CR, Schwarz M, Moulin P, Terranova R, Moggs JG. Luisier R, et al. Among authors: scheer n. Toxicol Sci. 2014 Jun;139(2):501-11. doi: 10.1093/toxsci/kfu038. Epub 2014 Apr 1. Toxicol Sci. 2014. PMID: 24690595
42 results