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Lamin A/C promotes DNA base excision repair.
Maynard S, Keijzers G, Akbari M, Ezra MB, Hall A, Morevati M, Scheibye-Knudsen M, Gonzalo S, Bartek J, Bohr VA. Maynard S, et al. Nucleic Acids Res. 2019 Dec 16;47(22):11709-11728. doi: 10.1093/nar/gkz912. Nucleic Acids Res. 2019. PMID: 31647095 Free PMC article.
Mitochondrial base excision repair assays.
Maynard S, de Souza-Pinto NC, Scheibye-Knudsen M, Bohr VA. Maynard S, et al. Methods. 2010 Aug;51(4):416-25. doi: 10.1016/j.ymeth.2010.02.020. Epub 2010 Feb 25. Methods. 2010. PMID: 20188838 Free PMC article. Review.
Negative regulation of STAT3 protein-mediated cellular respiration by SIRT1 protein.
Bernier M, Paul RK, Martin-Montalvo A, Scheibye-Knudsen M, Song S, He HJ, Armour SM, Hubbard BP, Bohr VA, Wang L, Zong Y, Sinclair DA, de Cabo R. Bernier M, et al. J Biol Chem. 2011 Jun 3;286(22):19270-9. doi: 10.1074/jbc.M110.200311. Epub 2011 Apr 5. J Biol Chem. 2011. PMID: 21467030 Free PMC article.
SRT1720 improves survival and healthspan of obese mice.
Minor RK, Baur JA, Gomes AP, Ward TM, Csiszar A, Mercken EM, Abdelmohsen K, Shin YK, Canto C, Scheibye-Knudsen M, Krawczyk M, Irusta PM, Martín-Montalvo A, Hubbard BP, Zhang Y, Lehrmann E, White AA, Price NL, Swindell WR, Pearson KJ, Becker KG, Bohr VA, Gorospe M, Egan JM, Talan MI, Auwerx J, Westphal CH, Ellis JL, Ungvari Z, Vlasuk GP, Elliott PJ, Sinclair DA, de Cabo R. Minor RK, et al. Sci Rep. 2011;1:70. doi: 10.1038/srep00070. Epub 2011 Aug 18. Sci Rep. 2011. PMID: 22355589 Free PMC article.
Sporadic Alzheimer disease fibroblasts display an oxidative stress phenotype.
Ramamoorthy M, Sykora P, Scheibye-Knudsen M, Dunn C, Kasmer C, Zhang Y, Becker KG, Croteau DL, Bohr VA. Ramamoorthy M, et al. Free Radic Biol Med. 2012 Sep 15;53(6):1371-80. doi: 10.1016/j.freeradbiomed.2012.07.018. Epub 2012 Aug 3. Free Radic Biol Med. 2012. PMID: 22885031 Free PMC article.
Mitochondrial deficiency in Cockayne syndrome.
Scheibye-Knudsen M, Croteau DL, Bohr VA. Scheibye-Knudsen M, et al. Mech Ageing Dev. 2013 May-Jun;134(5-6):275-83. doi: 10.1016/j.mad.2013.02.007. Epub 2013 Feb 19. Mech Ageing Dev. 2013. PMID: 23435289 Free PMC article. Review.
Metformin improves healthspan and lifespan in mice.
Martin-Montalvo A, Mercken EM, Mitchell SJ, Palacios HH, Mote PL, Scheibye-Knudsen M, Gomes AP, Ward TM, Minor RK, Blouin MJ, Schwab M, Pollak M, Zhang Y, Yu Y, Becker KG, Bohr VA, Ingram DK, Sinclair DA, Wolf NS, Spindler SR, Bernier M, de Cabo R. Martin-Montalvo A, et al. Nat Commun. 2013;4:2192. doi: 10.1038/ncomms3192. Nat Commun. 2013. PMID: 23900241 Free PMC article.
76 results