Schellekens H - Search Results

1

Interferon Beta: From Molecular Level to Therapeutic Effects.

Haji Abdolvahab M, Mofrad MR, Schellekens H. Haji Abdolvahab M, et al. Among authors: schellekens h. Int Rev Cell Mol Biol. 2016;326:343-72. doi: 10.1016/bs.ircmb.2016.06.001. Epub 2016 Jul 20. Int Rev Cell Mol Biol. 2016. PMID: 27572132 Review.

2

The effects of dodecyl maltoside and sodium dodecyl sulfate surfactants on the stability and aggregation of recombinant interferon Beta-1b.

Haji Abdolvahab M, Fazeli A, Fazeli MR, Brinks V, Schellekens H. Haji Abdolvahab M, et al. Among authors: schellekens h. J Interferon Cytokine Res. 2014 Nov;34(11):894-901. doi: 10.1089/jir.2013.0131. Epub 2014 Jun 23. J Interferon Cytokine Res. 2014. PMID: 24956236

3

Effect of arginine on pre-nucleus stage of interferon beta-1b aggregation.

Fazeli A, Haji-Abdolvahab M, Shojaosadati SA, Schellekens H, Khalifeh K, Moosavi-Movahedi AA, Fazeli MR. Fazeli A, et al. Among authors: schellekens h. AAPS PharmSciTech. 2014 Dec;15(6):1619-29. doi: 10.1208/s12249-014-0192-x. Epub 2014 Aug 21. AAPS PharmSciTech. 2014. PMID: 25142823 Free PMC article.

4

On the role of aggregates in the immunogenicity of recombinant human interferon beta in patients with multiple sclerosis.

van Beers MM, Jiskoot W, Schellekens H. van Beers MM, et al. Among authors: schellekens h. J Interferon Cytokine Res. 2010 Oct;30(10):767-75. doi: 10.1089/jir.2010.0086. J Interferon Cytokine Res. 2010. PMID: 20874254 Review.

5

Effect of treatment regimen on the immunogenicity of human interferon Beta in immune tolerant mice.

Kijanka G, Jiskoot W, Schellekens H, Brinks V. Kijanka G, et al. Among authors: schellekens h. Pharm Res. 2013 Jun;30(6):1553-60. doi: 10.1007/s11095-013-0992-9. Epub 2013 Jan 30. Pharm Res. 2013. PMID: 23361590

6

A modified immune tolerant mouse model to study the immunogenicity of recombinant human interferon beta.

Abdolvahab MH, Brinks V, Schellekens H. Abdolvahab MH, et al. Among authors: schellekens h. J Immunol Methods. 2014 Dec 15;415:17-23. doi: 10.1016/j.jim.2014.10.004. Epub 2014 Oct 18. J Immunol Methods. 2014. PMID: 25450255

7

Development of ADA against recombinant human interferon beta in immune tolerant mice requires rapid recruitment of CD4⁺ T cells, induces formation of germinal centers but lacks susceptibility for (most) adjuvants.

Kijanka G, Sauerborn M, Boon L, Schellekens H, Brinks V. Kijanka G, et al. Among authors: schellekens h. J Pharm Sci. 2015 Feb;104(2):396-406. doi: 10.1002/jps.24170. Epub 2014 Sep 12. J Pharm Sci. 2015. PMID: 25219665

8

An Albumin-Free Formulation for Escherichia coli-Derived Interferon Beta-1b with Decreased Immunogenicity in Immune Tolerant Mice.

Abdolvahab MH, Fazeli A, Radmalekshahi M, Nejadnik MR, Fazeli MR, Schellekens H. Abdolvahab MH, et al. Among authors: schellekens h. J Interferon Cytokine Res. 2016 Mar;36(3):192-203. doi: 10.1089/jir.2015.0110. Epub 2016 Jan 29. J Interferon Cytokine Res. 2016. PMID: 26824268

9

Hybrid transgenic immune tolerant mouse model for assessing the breaking of B cell tolerance by human interferon beta.

van Beers MM, Sauerborn M, Gilli F, Hermeling S, Brinks V, Schellekens H, Jiskoot W. van Beers MM, et al. Among authors: schellekens h. J Immunol Methods. 2010 Jan 31;352(1-2):32-7. doi: 10.1016/j.jim.2009.10.005. Epub 2009 Oct 24. J Immunol Methods. 2010. PMID: 19857496

10

Recommendations for clinical use of data on neutralising antibodies to interferon-beta therapy in multiple sclerosis.

Polman CH, Bertolotto A, Deisenhammer F, Giovannoni G, Hartung HP, Hemmer B, Killestein J, McFarland HF, Oger J, Pachner AR, Petkau J, Reder AT, Reingold SC, Schellekens H, Sørensen PS. Polman CH, et al. Among authors: schellekens h. Lancet Neurol. 2010 Jul;9(7):740-50. doi: 10.1016/S1474-4422(10)70103-4. Lancet Neurol. 2010. PMID: 20610349

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