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The IL-6/sIL-6R complex as a novel target for therapeutic approaches.
Rose-John S, Waetzig GH, Scheller J, Grötzinger J, Seegert D. Rose-John S, et al. Among authors: scheller j. Expert Opin Ther Targets. 2007 May;11(5):613-24. doi: 10.1517/14728222.11.5.613. Expert Opin Ther Targets. 2007. PMID: 17465721 Review.
No inhibition of IL-27 signaling by soluble gp130.
Scheller J, Schuster B, Hölscher C, Yoshimoto T, Rose-John S. Scheller J, et al. Biochem Biophys Res Commun. 2005 Jan 28;326(4):724-8. doi: 10.1016/j.bbrc.2004.11.098. Biochem Biophys Res Commun. 2005. PMID: 15607729
IL-6 transsignaling: the in vivo consequences.
Jones SA, Richards PJ, Scheller J, Rose-John S. Jones SA, et al. Among authors: scheller j. J Interferon Cytokine Res. 2005 May;25(5):241-53. doi: 10.1089/jir.2005.25.241. J Interferon Cytokine Res. 2005. PMID: 15871661 Review.
Forced dimerization of gp130 leads to constitutive STAT3 activation, cytokine-independent growth, and blockade of differentiation of embryonic stem cells.
Stuhlmann-Laeisz C, Lang S, Chalaris A, Krzysztof P, Enge S, Eichler J, Klingmüller U, Samuel M, Ernst M, Rose-John S, Scheller J. Stuhlmann-Laeisz C, et al. Among authors: scheller j. Mol Biol Cell. 2006 Jul;17(7):2986-95. doi: 10.1091/mbc.e05-12-1129. Epub 2006 Apr 19. Mol Biol Cell. 2006. PMID: 16624864 Free PMC article.
Interleukin-6 and its receptor: from bench to bedside.
Scheller J, Rose-John S. Scheller J, et al. Med Microbiol Immunol. 2006 Dec;195(4):173-83. doi: 10.1007/s00430-006-0019-9. Epub 2006 May 31. Med Microbiol Immunol. 2006. PMID: 16741736 Review.
219 results