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Signal perception and transduction: the role of protein kinases.
Schenk PW, Snaar-Jagalska BE. Schenk PW, et al. Biochim Biophys Acta. 1999 Feb 4;1449(1):1-24. doi: 10.1016/s0167-4889(98)00178-5. Biochim Biophys Acta. 1999. PMID: 10076047 Review.
A serpentine receptor-dependent, Gbeta- and Ca(2+) influx-independent pathway regulates mitogen-activated protein kinase ERK2 in Dictyostelium.
Schenk PW, Nebl T, Fisher PR, Snaar-Jagalska BE. Schenk PW, et al. Biochem Biophys Res Commun. 1999 Jul 5;260(2):504-9. doi: 10.1006/bbrc.1999.0862. Biochem Biophys Res Commun. 1999. PMID: 10403797
Involvement of cyclic AMP cell surface receptors and G-proteins in signal transduction during slug migration of Dictyostelium discoideum.
Schenk PW, Van Es S, Kesbeke F, Snaar-Jagalska BE. Schenk PW, et al. Dev Biol. 1991 May;145(1):110-8. doi: 10.1016/0012-1606(91)90217-q. Dev Biol. 1991. PMID: 1850366
Dual role of cAMP and involvement of both G-proteins and ras in regulation of ERK2 in Dictyostelium discoideum.
Knetsch ML, Epskamp SJ, Schenk PW, Wang Y, Segall JE, Snaar-Jagalska BE. Knetsch ML, et al. Among authors: schenk pw. EMBO J. 1996 Jul 1;15(13):3361-8. EMBO J. 1996. PMID: 8670837 Free PMC article.
Lysophosphatidic acid- and Gbeta-dependent activation of Dictyostelium MAP kinase ERK2.
Schenk PW, Epskamp SJ, Knetsch ML, Harten V, Lagendijk EL, van Duijn B, Snaar-Jagalska BE. Schenk PW, et al. Biochem Biophys Res Commun. 2001 Apr 6;282(3):765-72. doi: 10.1006/bbrc.2001.4649. Biochem Biophys Res Commun. 2001. PMID: 11401529
A genome-wide screening in Saccharomyces cerevisiae for genes that confer resistance to the anticancer agent cisplatin.
Burger H, Capello A, Schenk PW, Stoter G, Brouwer J, Nooter K. Burger H, et al. Among authors: schenk pw. Biochem Biophys Res Commun. 2000 Mar 24;269(3):767-74. doi: 10.1006/bbrc.2000.2361. Biochem Biophys Res Commun. 2000. PMID: 10720490
SKY1 is involved in cisplatin-induced cell kill in Saccharomyces cerevisiae, and inactivation of its human homologue, SRPK1, induces cisplatin resistance in a human ovarian carcinoma cell line.
Schenk PW, Boersma AW, Brandsma JA, den Dulk H, Burger H, Stoter G, Brouwer J, Nooter K. Schenk PW, et al. Cancer Res. 2001 Oct 1;61(19):6982-6. Cancer Res. 2001. PMID: 11585720
Inactivation of the Saccharomyces cerevisiae SKY1 gene induces a specific modification of the yeast anticancer drug sensitivity profile accompanied by a mutator phenotype.
Schenk PW, Boersma AW, Brok M, Burger H, Stoter G, Nooter K. Schenk PW, et al. Mol Pharmacol. 2002 Mar;61(3):659-66. doi: 10.1124/mol.61.3.659. Mol Pharmacol. 2002. PMID: 11854447
Anticancer drug resistance induced by disruption of the Saccharomyces cerevisiae NPR2 gene: a novel component involved in cisplatin- and doxorubicin-provoked cell kill.
Schenk PW, Brok M, Boersma AW, Brandsma JA, Den Dulk H, Burger H, Stoter G, Brouwer J, Nooter K. Schenk PW, et al. Mol Pharmacol. 2003 Aug;64(2):259-68. doi: 10.1124/mol.64.2.259. Mol Pharmacol. 2003. PMID: 12869630
Resistance to platinum-containing chemotherapy in testicular germ cell tumors is associated with downregulation of the protein kinase SRPK1.
Schenk PW, Stoop H, Bokemeyer C, Mayer F, Stoter G, Oosterhuis JW, Wiemer E, Looijenga LH, Nooter K. Schenk PW, et al. Neoplasia. 2004 Jul-Aug;6(4):297-301. doi: 10.1593/neo.03406. Neoplasia. 2004. PMID: 15256051 Free PMC article.
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