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Combined overexpression of SIRT1 and knockout of GCN5 in adult skeletal muscle does not affect glucose homeostasis or exercise performance in mice.
Svensson K, Tahvilian S, Martins VF, Dent JR, Lemanek A, Barooni N, Greyslak K, McCurdy CE, Schenk S. Svensson K, et al. Among authors: schenk s. Am J Physiol Endocrinol Metab. 2020 Feb 1;318(2):E145-E151. doi: 10.1152/ajpendo.00370.2019. Epub 2019 Dec 3. Am J Physiol Endocrinol Metab. 2020. PMID: 31794263 Free PMC article.
Sirtuin 1 (SIRT1) deacetylase activity is not required for mitochondrial biogenesis or peroxisome proliferator-activated receptor-gamma coactivator-1alpha (PGC-1alpha) deacetylation following endurance exercise.
Philp A, Chen A, Lan D, Meyer GA, Murphy AN, Knapp AE, Olfert IM, McCurdy CE, Marcotte GR, Hogan MC, Baar K, Schenk S. Philp A, et al. Among authors: schenk s. J Biol Chem. 2011 Sep 2;286(35):30561-30570. doi: 10.1074/jbc.M111.261685. Epub 2011 Jul 11. J Biol Chem. 2011. PMID: 21757760 Free PMC article.
NAD(+)/NADH and skeletal muscle mitochondrial adaptations to exercise.
White AT, Schenk S. White AT, et al. Among authors: schenk s. Am J Physiol Endocrinol Metab. 2012 Aug 1;303(3):E308-21. doi: 10.1152/ajpendo.00054.2012. Epub 2012 Mar 20. Am J Physiol Endocrinol Metab. 2012. PMID: 22436696 Free PMC article. Review.
522 results