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Prolonged maturation and enhanced transduction of dendritic cells migrated from human skin explants after in situ delivery of CD40-targeted adenoviral vectors.
de Gruijl TD, Luykx-de Bakker SA, Tillman BW, van den Eertwegh AJ, Buter J, Lougheed SM, van der Bij GJ, Safer AM, Haisma HJ, Curiel DT, Scheper RJ, Pinedo HM, Gerritsen WR. de Gruijl TD, et al. Among authors: scheper rj. J Immunol. 2002 Nov 1;169(9):5322-31. doi: 10.4049/jimmunol.169.9.5322. J Immunol. 2002. PMID: 12391253
In vitro priming of tumor-specific cytotoxic T lymphocytes using allogeneic dendritic cells derived from the human MUTZ-3 cell line.
Santegoets SJ, Schreurs MW, Masterson AJ, Liu YP, Goletz S, Baumeister H, Kueter EW, Lougheed SM, van den Eertwegh AJ, Scheper RJ, Hooijberg E, de Gruijl TD. Santegoets SJ, et al. Among authors: scheper rj. Cancer Immunol Immunother. 2006 Dec;55(12):1480-90. doi: 10.1007/s00262-006-0142-x. Epub 2006 Feb 9. Cancer Immunol Immunother. 2006. PMID: 16468034
Selective transduction of dendritic cells in human lymph nodes and superior induction of high-avidity melanoma-reactive cytotoxic T cells by a CD40-targeted adenovirus.
Hangalapura BN, Oosterhoff D, Aggarwal S, Wijnands PG, van de Ven R, Santegoets SJ, van den Tol MP, Hooijberg E, Pereboev A, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Hangalapura BN, et al. Among authors: scheper rj. J Immunother. 2010 Sep;33(7):706-15. doi: 10.1097/CJI.0b013e3181eccbd4. J Immunother. 2010. PMID: 20664356
Delivery route, MyD88 signaling and cross-priming events determine the anti-tumor efficacy of an adenovirus based melanoma vaccine.
Hangalapura BN, Oosterhoff D, Gupta T, de Groot J, Wijnands PG, van Beusechem VW, den Haan J, Tüting T, van den Eertwegh AJ, Curiel DT, Scheper RJ, de Gruijl TD. Hangalapura BN, et al. Among authors: scheper rj. Vaccine. 2011 Mar 9;29(12):2313-21. doi: 10.1016/j.vaccine.2011.01.022. Epub 2011 Jan 25. Vaccine. 2011. PMID: 21272606 Free PMC article.
Potent antitumor immunity generated by a CD40-targeted adenoviral vaccine.
Hangalapura BN, Oosterhoff D, de Groot J, Boon L, Tüting T, van den Eertwegh AJ, Gerritsen WR, van Beusechem VW, Pereboev A, Curiel DT, Scheper RJ, de Gruijl TD. Hangalapura BN, et al. Among authors: scheper rj. Cancer Res. 2011 Sep 1;71(17):5827-37. doi: 10.1158/0008-5472.CAN-11-0804. Epub 2011 Jul 11. Cancer Res. 2011. PMID: 21747119 Free article.
CD40-targeted adenoviral GM-CSF gene transfer enhances and prolongs the maturation of human CML-derived dendritic cells upon cytokine deprivation.
Stam AG, Santegoets SJ, Westers TM, Sombroek CC, Janssen JJ, Tillman BW, van de Loosdrecht AA, Pinedo HM, Curiel DT, Ossenkoppele GJ, Scheper RJ, de Gruijl TD. Stam AG, et al. Among authors: scheper rj. Br J Cancer. 2003 Oct 6;89(7):1162-5. doi: 10.1038/sj.bjc.6601225. Br J Cancer. 2003. PMID: 14520439 Free PMC article.
508 results