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Enhanced expression of heat shock protein 70 (hsp70) and heat shock factor 1 (HSF1) activation in rheumatoid arthritis synovial tissue. Differential regulation of hsp70 expression and hsf1 activation in synovial fibroblasts by proinflammatory cytokines, shear stress, and antiinflammatory drugs.
Schett G, Redlich K, Xu Q, Bizan P, Gröger M, Tohidast-Akrad M, Kiener H, Smolen J, Steiner G. Schett G, et al. J Clin Invest. 1998 Jul 15;102(2):302-11. doi: 10.1172/JCI2465. J Clin Invest. 1998. PMID: 9664071 Free PMC article.
The stressed synovium.
Schett G, Tohidast-Akrad M, Steiner G, Smolen J. Schett G, et al. Arthritis Res. 2001;3(2):80-6. doi: 10.1186/ar144. Epub 2001 Jan 9. Arthritis Res. 2001. PMID: 11178114 Free PMC article. Review.
Adenovirus-based overexpression of tissue inhibitor of metalloproteinases 1 reduces tissue damage in the joints of tumor necrosis factor alpha transgenic mice.
Schett G, Hayer S, Tohidast-Akrad M, Schmid BJ, Lang S, Türk B, Kainberger F, Haralambous S, Kollias G, Newby AC, Xu Q, Steiner G, Smolen J. Schett G, et al. Arthritis Rheum. 2001 Dec;44(12):2888-98. doi: 10.1002/1529-0131(200112)44:12<2888::aid-art477>;2-3. Arthritis Rheum. 2001. PMID: 11762950
Osteoclasts are essential for TNF-alpha-mediated joint destruction.
Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, Steiner G, Smolen JS, Wagner EF, Schett G. Redlich K, et al. Among authors: schett g. J Clin Invest. 2002 Nov;110(10):1419-27. doi: 10.1172/JCI15582. J Clin Invest. 2002. PMID: 12438440 Free PMC article.
The role of osteoprotegerin in arthritis.
Schett G, Redlich K, Smolen JS. Schett G, et al. Arthritis Res Ther. 2003;5(5):239-45. doi: 10.1186/ar990. Epub 2003 Aug 8. Arthritis Res Ther. 2003. PMID: 12932284 Free PMC article. Review.
Single and combined inhibition of tumor necrosis factor, interleukin-1, and RANKL pathways in tumor necrosis factor-induced arthritis: effects on synovial inflammation, bone erosion, and cartilage destruction.
Zwerina J, Hayer S, Tohidast-Akrad M, Bergmeister H, Redlich K, Feige U, Dunstan C, Kollias G, Steiner G, Smolen J, Schett G. Zwerina J, et al. Among authors: schett g. Arthritis Rheum. 2004 Jan;50(1):277-90. doi: 10.1002/art.11487. Arthritis Rheum. 2004. PMID: 14730626
Repair of local bone erosions and reversal of systemic bone loss upon therapy with anti-tumor necrosis factor in combination with osteoprotegerin or parathyroid hormone in tumor necrosis factor-mediated arthritis.
Redlich K, Görtz B, Hayer S, Zwerina J, Doerr N, Kostenuik P, Bergmeister H, Kollias G, Steiner G, Smolen JS, Schett G. Redlich K, et al. Among authors: schett g. Am J Pathol. 2004 Feb;164(2):543-55. doi: 10.1016/S0002-9440(10)63144-6. Am J Pathol. 2004. PMID: 14742260 Free PMC article.
Soluble RANKL and risk of nontraumatic fracture.
Schett G, Kiechl S, Redlich K, Oberhollenzer F, Weger S, Egger G, Mayr A, Jocher J, Xu Q, Pietschmann P, Teitelbaum S, Smolen J, Willeit J. Schett G, et al. JAMA. 2004 Mar 3;291(9):1108-13. doi: 10.1001/jama.291.9.1108. JAMA. 2004. PMID: 14996780
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