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The EGF-CFC gene family in vertebrate development.
Shen MM, Schier AF. Shen MM, et al. Among authors: schier af. Trends Genet. 2000 Jul;16(7):303-9. doi: 10.1016/s0168-9525(00)02006-0. Trends Genet. 2000. PMID: 10858660 Review.
Loss-of-function mutations in the EGF-CFC gene CFC1 are associated with human left-right laterality defects.
Bamford RN, Roessler E, Burdine RD, Saplako─člu U, dela Cruz J, Splitt M, Goodship JA, Towbin J, Bowers P, Ferrero GB, Marino B, Schier AF, Shen MM, Muenke M, Casey B. Bamford RN, et al. Among authors: schier af. Nat Genet. 2000 Nov;26(3):365-9. doi: 10.1038/81695. Nat Genet. 2000. PMID: 11062482
The EGF-CFC protein one-eyed pinhead is essential for nodal signaling.
Gritsman K, Zhang J, Cheng S, Heckscher E, Talbot WS, Schier AF. Gritsman K, et al. Among authors: schier af. Cell. 1999 Apr 2;97(1):121-32. doi: 10.1016/s0092-8674(00)80720-5. Cell. 1999. PMID: 10199408
Nodal signalling in vertebrate development.
Schier AF, Shen MM. Schier AF, et al. Nature. 2000 Jan 27;403(6768):385-9. doi: 10.1038/35000126. Nature. 2000. PMID: 10667782 Review.
Conserved requirement for EGF-CFC genes in vertebrate left-right axis formation.
Yan YT, Gritsman K, Ding J, Burdine RD, Corrales JD, Price SM, Talbot WS, Schier AF, Shen MM. Yan YT, et al. Among authors: schier af. Genes Dev. 1999 Oct 1;13(19):2527-37. doi: 10.1101/gad.13.19.2527. Genes Dev. 1999. PMID: 10521397 Free PMC article.
Positional cloning identifies zebrafish one-eyed pinhead as a permissive EGF-related ligand required during gastrulation.
Zhang J, Talbot WS, Schier AF. Zhang J, et al. Among authors: schier af. Cell. 1998 Jan 23;92(2):241-51. doi: 10.1016/s0092-8674(00)80918-6. Cell. 1998. PMID: 9458048
The zebrafish organizer.
Schier AF, Talbot WS. Schier AF, et al. Curr Opin Genet Dev. 1998 Aug;8(4):464-71. doi: 10.1016/s0959-437x(98)80119-6. Curr Opin Genet Dev. 1998. PMID: 9729724 Review.
Lefty blocks a subset of TGFbeta signals by antagonizing EGF-CFC coreceptors.
Cheng SK, Olale F, Brivanlou AH, Schier AF. Cheng SK, et al. Among authors: schier af. PLoS Biol. 2004 Feb;2(2):E30. doi: 10.1371/journal.pbio.0020030. Epub 2004 Feb 17. PLoS Biol. 2004. PMID: 14966532 Free PMC article.
A loss-of-function mutation in the CFC domain of TDGF1 is associated with human forebrain defects.
de la Cruz JM, Bamford RN, Burdine RD, Roessler E, Barkovich AJ, Donnai D, Schier AF, Muenke M. de la Cruz JM, et al. Among authors: schier af. Hum Genet. 2002 May;110(5):422-8. doi: 10.1007/s00439-002-0709-3. Epub 2002 Apr 10. Hum Genet. 2002. PMID: 12073012
EGF-CFC proteins are essential coreceptors for the TGF-beta signals Vg1 and GDF1.
Cheng SK, Olale F, Bennett JT, Brivanlou AH, Schier AF. Cheng SK, et al. Among authors: schier af. Genes Dev. 2003 Jan 1;17(1):31-6. doi: 10.1101/gad.1041203. Genes Dev. 2003. PMID: 12514096 Free PMC article.
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