Schier AF - Search Results

1

Efficient CRISPR-Cas9-mediated generation of knockin human pluripotent stem cells lacking undesired mutations at the targeted locus.

Merkle FT, Neuhausser WM, Santos D, Valen E, Gagnon JA, Maas K, Sandoe J, Schier AF, Eggan K. Merkle FT, et al. Among authors: schier af. Cell Rep. 2015 May 12;11(6):875-883. doi: 10.1016/j.celrep.2015.04.007. Epub 2015 Apr 30. Cell Rep. 2015. PMID: 25937281 Free PMC article.

2

Efficient mutagenesis by Cas9 protein-mediated oligonucleotide insertion and large-scale assessment of single-guide RNAs.

Gagnon JA, Valen E, Thyme SB, Huang P, Akhmetova L, Pauli A, Montague TG, Zimmerman S, Richter C, Schier AF. Gagnon JA, et al. Among authors: schier af. PLoS One. 2014 May 29;9(5):e98186. doi: 10.1371/journal.pone.0098186. eCollection 2014. PLoS One. 2014. PMID: 24873830 Free PMC article.

3

Whole-organism lineage tracing by combinatorial and cumulative genome editing.

McKenna A, Findlay GM, Gagnon JA, Horwitz MS, Schier AF, Shendure J. McKenna A, et al. Among authors: schier af. Science. 2016 Jul 29;353(6298):aaf7907. doi: 10.1126/science.aaf7907. Epub 2016 May 26. Science. 2016. PMID: 27229144 Free PMC article.

4

Internal guide RNA interactions interfere with Cas9-mediated cleavage.

Thyme SB, Akhmetova L, Montague TG, Valen E, Schier AF. Thyme SB, et al. Among authors: schier af. Nat Commun. 2016 Jun 10;7:11750. doi: 10.1038/ncomms11750. Nat Commun. 2016. PMID: 27282953 Free PMC article.

5

Generation of neuropeptidergic hypothalamic neurons from human pluripotent stem cells.

Merkle FT, Maroof A, Wataya T, Sasai Y, Studer L, Eggan K, Schier AF. Merkle FT, et al. Among authors: schier af. Development. 2015 Feb 15;142(4):633-43. doi: 10.1242/dev.117978. Development. 2015. PMID: 25670790 Free PMC article.

6

Evolutionarily conserved regulation of hypocretin neuron specification by Lhx9.

Liu J, Merkle FT, Gandhi AV, Gagnon JA, Woods IG, Chiu CN, Shimogori T, Schier AF, Prober DA. Liu J, et al. Among authors: schier af. Development. 2015 Mar 15;142(6):1113-24. doi: 10.1242/dev.117424. Epub 2015 Feb 27. Development. 2015. PMID: 25725064 Free PMC article.

7

Identifying (non-)coding RNAs and small peptides: challenges and opportunities.

Pauli A, Valen E, Schier AF. Pauli A, et al. Among authors: schier af. Bioessays. 2015 Jan;37(1):103-12. doi: 10.1002/bies.201400103. Epub 2014 Oct 24. Bioessays. 2015. PMID: 25345765 Free PMC article. Review.

8

Zebrafish dscaml1 Deficiency Impairs Retinal Patterning and Oculomotor Function.

Ma M, Ramirez AD, Wang T, Roberts RL, Harmon KE, Schoppik D, Sharma A, Kuang C, Goei SL, Gagnon JA, Zimmerman S, Tsai SQ, Reyon D, Joung JK, Aksay ERF, Schier AF, Pan YA. Ma M, et al. Among authors: schier af. J Neurosci. 2020 Jan 2;40(1):143-158. doi: 10.1523/JNEUROSCI.1783-19.2019. Epub 2019 Nov 4. J Neurosci. 2020. PMID: 31685652 Free PMC article.

9

High-resolution sequencing and modeling identifies distinct dynamic RNA regulatory strategies.

Rabani M, Raychowdhury R, Jovanovic M, Rooney M, Stumpo DJ, Pauli A, Hacohen N, Schier AF, Blackshear PJ, Friedman N, Amit I, Regev A. Rabani M, et al. Among authors: schier af. Cell. 2014 Dec 18;159(7):1698-710. doi: 10.1016/j.cell.2014.11.015. Epub 2014 Dec 11. Cell. 2014. PMID: 25497548 Free PMC article.

10

Polq-Mediated End Joining Is Essential for Surviving DNA Double-Strand Breaks during Early Zebrafish Development.

Thyme SB, Schier AF. Thyme SB, et al. Among authors: schier af. Cell Rep. 2016 Apr 26;15(4):707-714. doi: 10.1016/j.celrep.2016.03.072. Epub 2016 Apr 14. Cell Rep. 2016. PMID: 27149851 Free PMC article.

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