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Influenza virus drug resistance: a time-sampled population genetics perspective.
Foll M, Poh YP, Renzette N, Ferrer-Admetlla A, Bank C, Shim H, Malaspinas AS, Ewing G, Liu P, Wegmann D, Caffrey DR, Zeldovich KB, Bolon DN, Wang JP, Kowalik TF, Schiffer CA, Finberg RW, Jensen JD. Foll M, et al. Among authors: schiffer ca. PLoS Genet. 2014 Feb 27;10(2):e1004185. doi: 10.1371/journal.pgen.1004185. eCollection 2014 Feb. PLoS Genet. 2014. PMID: 24586206 Free PMC article.
Positive Selection Drives Preferred Segment Combinations during Influenza Virus Reassortment.
Zeldovich KB, Liu P, Renzette N, Foll M, Pham ST, Venev SV, Gallagher GR, Bolon DN, Kurt-Jones EA, Jensen JD, Caffrey DR, Schiffer CA, Kowalik TF, Wang JP, Finberg RW. Zeldovich KB, et al. Among authors: schiffer ca. Mol Biol Evol. 2015 Jun;32(6):1519-32. doi: 10.1093/molbev/msv044. Epub 2015 Feb 23. Mol Biol Evol. 2015. PMID: 25713211 Free PMC article.
Elucidating the Interdependence of Drug Resistance from Combinations of Mutations.
Ragland DA, Whitfield TW, Lee SK, Swanstrom R, Zeldovich KB, Kurt-Yilmaz N, Schiffer CA. Ragland DA, et al. Among authors: schiffer ca. J Chem Theory Comput. 2017 Nov 14;13(11):5671-5682. doi: 10.1021/acs.jctc.7b00601. Epub 2017 Oct 9. J Chem Theory Comput. 2017. PMID: 28915040 Free PMC article.
CRISPR-Cas9-mediated saturated mutagenesis screen predicts clinical drug resistance with improved accuracy.
Ma L, Boucher JI, Paulsen J, Matuszewski S, Eide CA, Ou J, Eickelberg G, Press RD, Zhu LJ, Druker BJ, Branford S, Wolfe SA, Jensen JD, Schiffer CA, Green MR, Bolon DN. Ma L, et al. Among authors: schiffer ca. Proc Natl Acad Sci U S A. 2017 Oct 31;114(44):11751-11756. doi: 10.1073/pnas.1708268114. Epub 2017 Oct 16. Proc Natl Acad Sci U S A. 2017. PMID: 29078326 Free PMC article.
546 results