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Critical role for the kinesin KIF3A in the HIV life cycle in primary human macrophages.
Gaudin R, de Alencar BC, Jouve M, Bèrre S, Le Bouder E, Schindler M, Varthaman A, Gobert FX, Benaroch P. Gaudin R, et al. Among authors: Schindler M. J Cell Biol. 2012 Oct 29;199(3):467-79. doi: 10.1083/jcb.201201144. Epub 2012 Oct 22. J Cell Biol. 2012. PMID: 23091068 Free PMC article.
Virion encapsidated HIV-1 Vpr induces NFAT to prime non-activated T cells for productive infection.
Höhne K, Businger R, van Nuffel A, Bolduan S, Koppensteiner H, Baeyens A, Vermeire J, Malatinkova E, Verhasselt B, Schindler M. Höhne K, et al. Among authors: Schindler M. Open Biol. 2016 Jul;6(7):160046. doi: 10.1098/rsob.160046. Open Biol. 2016. PMID: 27383627 Free PMC article.
Upon NFAT inhibition, Vpr did not augment resting T-cell infection, and showed reduced G2/M arrest and LTR transactivation. Altogether, Vpr renders unstimulated T cells more permissive for productive HIV-1 infection and stimulates activation of productively infected as well as virus-exposed T cells. ...
Upon NFAT inhibition, Vpr did not augment resting T-cell infection, and showed reduced G2/M arrest and LTR transactivation. Altogethe …
Semen-derived amyloid fibrils drastically enhance HIV infection.
Münch J, Rücker E, Ständker L, Adermann K, Goffinet C, Schindler M, Wildum S, Chinnadurai R, Rajan D, Specht A, Giménez-Gallego G, Sánchez PC, Fowler DM, Koulov A, Kelly JW, Mothes W, Grivel JC, Margolis L, Keppler OT, Forssmann WG, Kirchhoff F. Münch J, et al. Among authors: Schindler M. Cell. 2007 Dec 14;131(6):1059-71. doi: 10.1016/j.cell.2007.10.014. Cell. 2007. PMID: 18083097
Nef-mediated suppression of T cell activation was lost in a lentiviral lineage that gave rise to HIV-1.
Schindler M, Münch J, Kutsch O, Li H, Santiago ML, Bibollet-Ruche F, Müller-Trutwin MC, Novembre FJ, Peeters M, Courgnaud V, Bailes E, Roques P, Sodora DL, Silvestri G, Sharp PM, Hahn BH, Kirchhoff F. Schindler M, et al. Cell. 2006 Jun 16;125(6):1055-67. doi: 10.1016/j.cell.2006.04.033. Cell. 2006. PMID: 16777597
HIV-1 assembly in macrophages.
Benaroch P, Billard E, Gaudin R, Schindler M, Jouve M. Benaroch P, et al. Among authors: Schindler M. Retrovirology. 2010 Apr 7;7:29. doi: 10.1186/1742-4690-7-29. Retrovirology. 2010. PMID: 20374631 Free PMC article. Review.
Human immunodeficiency virus type 1 nef expression prevents AP-2-mediated internalization of the major histocompatibility complex class II-associated invariant chain.
Toussaint H, Gobert FX, Schindler M, Banning C, Kozik P, Jouve M, Kirchhoff F, Benaroch P. Toussaint H, et al. Among authors: Schindler M. J Virol. 2008 Sep;82(17):8373-82. doi: 10.1128/JVI.00670-08. Epub 2008 Jul 2. J Virol. 2008. PMID: 18596106 Free PMC article.
Macrophage internal HIV-1 is protected from neutralizing antibodies.
Koppensteiner H, Banning C, Schneider C, Hohenberg H, Schindler M. Koppensteiner H, et al. Among authors: Schindler M. J Virol. 2012 Mar;86(5):2826-36. doi: 10.1128/JVI.05915-11. Epub 2011 Dec 28. J Virol. 2012. PMID: 22205742 Free PMC article.
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