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Characterization of the pyruvate kinase-encoding gene (pki1) of Trichoderma reesei.
Schindler M, Mach RL, Vollenhofer SK, Hodits R, Gruber F, Visser J, De Graaff L, Kubicek CP. Schindler M, et al. Gene. 1993 Aug 25;130(2):271-5. doi: 10.1016/0378-1119(93)90430-b. Gene. 1993. PMID: 8359694
Enhanced CD4 down-modulation by late stage HIV-1 nef alleles is associated with increased Env incorporation and viral replication.
Argañaraz ER, Schindler M, Kirchhoff F, Cortes MJ, Lama J. Argañaraz ER, et al. J Biol Chem. 2003 Sep 5;278(36):33912-9. doi: 10.1074/jbc.M303679200. Epub 2003 Jun 19. J Biol Chem. 2003. PMID: 12816953
A mechanism for tamoxifen-mediated inhibition of acidification.
Chen Y, Schindler M, Simon SM. Chen Y, et al. J Biol Chem. 1999 Jun 25;274(26):18364-73. doi: 10.1074/jbc.274.26.18364. J Biol Chem. 1999. PMID: 10373441
Single Nef proteins from HIV type 1 subtypes C and F fail to upregulate invariant chain cell surface expression but are active for other functions.
Turk G, Gundlach S, Carobene M, Schindler M, Salomon H, Benaroch P. Turk G, et al. AIDS Res Hum Retroviruses. 2009 Mar;25(3):285-96. doi: 10.1089/aid.2008.0132. AIDS Res Hum Retroviruses. 2009. PMID: 19327048
Conservation of Nef function across highly diverse lineages of SIVsmm.
Schmökel J, Li H, Bailes E, Schindler M, Silvestri G, Hahn BH, Apetrei C, Kirchhoff F. Schmökel J, et al. Retrovirology. 2009 Apr 9;6:36. doi: 10.1186/1742-4690-6-36. Retrovirology. 2009. PMID: 19358735 Free PMC article.
Tetherin-driven adaptation of Vpu and Nef function and the evolution of pandemic and nonpandemic HIV-1 strains.
Sauter D, Schindler M, Specht A, Landford WN, Münch J, Kim KA, Votteler J, Schubert U, Bibollet-Ruche F, Keele BF, Takehisa J, Ogando Y, Ochsenbauer C, Kappes JC, Ayouba A, Peeters M, Learn GH, Shaw G, Sharp PM, Bieniasz P, Hahn BH, Hatziioannou T, Kirchhoff F. Sauter D, et al. Cell Host Microbe. 2009 Nov 19;6(5):409-21. doi: 10.1016/j.chom.2009.10.004. Cell Host Microbe. 2009. PMID: 19917496 Free PMC article.
Thus, only HIV-1 M evolved a fully functional Vpu following the three independent cross-species transmissions that resulted in HIV-1 groups M, N, and O. This may explain why group M viruses are almost entirely responsible for the global HIV/AIDS pandemic....
Thus, only HIV-1 M evolved a fully functional Vpu following the three independent cross-species transmissions that resulted in HIV-1 …
Inefficient Nef-mediated downmodulation of CD3 and MHC-I correlates with loss of CD4+T cells in natural SIV infection.
Schindler M, Schmökel J, Specht A, Li H, Münch J, Khalid M, Sodora DL, Hahn BH, Silvestri G, Kirchhoff F. Schindler M, et al. PLoS Pathog. 2008 Jul 18;4(7):e1000107. doi: 10.1371/journal.ppat.1000107. PLoS Pathog. 2008. PMID: 18636106 Free PMC article.
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