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Structure of Escherichia coli pyridoxine 5'-phosphate oxidase in a tetragonal crystal form: insights into the mechanistic pathway of the enzyme.
Safo MK, Musayev FN, Schirch V. Safo MK, et al. Among authors: schirch v. Acta Crystallogr D Biol Crystallogr. 2005 May;61(Pt 5):599-604. doi: 10.1107/S0907444905005512. Epub 2005 Apr 20. Acta Crystallogr D Biol Crystallogr. 2005. PMID: 15858270
Crystal structure of the PdxY Protein from Escherichia coli.
Safo MK, Musayev FN, Hunt S, di Salvo ML, Scarsdale N, Schirch V. Safo MK, et al. Among authors: schirch v. J Bacteriol. 2004 Dec;186(23):8074-82. doi: 10.1128/JB.186.23.8074-8082.2004. J Bacteriol. 2004. PMID: 15547280 Free PMC article.
Structure and properties of recombinant human pyridoxine 5'-phosphate oxidase.
Musayev FN, Di Salvo ML, Ko TP, Schirch V, Safo MK. Musayev FN, et al. Among authors: schirch v. Protein Sci. 2003 Jul;12(7):1455-63. doi: 10.1110/ps.0356203. Protein Sci. 2003. PMID: 12824491 Free PMC article.
Location of the pteroylpolyglutamate-binding site on rabbit cytosolic serine hydroxymethyltransferase.
Fu TF, Scarsdale JN, Kazanina G, Schirch V, Wright HT. Fu TF, et al. Among authors: schirch v. J Biol Chem. 2003 Jan 24;278(4):2645-53. doi: 10.1074/jbc.M210649200. Epub 2002 Nov 15. J Biol Chem. 2003. PMID: 12438316
Role of proline residues in the folding of serine hydroxymethyltransferase.
Fu TF, Boja ES, Safo MK, Schirch V. Fu TF, et al. Among authors: schirch v. J Biol Chem. 2003 Aug 15;278(33):31088-94. doi: 10.1074/jbc.M303779200. Epub 2003 May 28. J Biol Chem. 2003. PMID: 12773539
Inactive mutants of human pyridoxine 5'-phosphate oxidase: a possible role for a noncatalytic pyridoxal 5'-phosphate tight binding site.
Ghatge MS, Karve SS, David TM, Ahmed MH, Musayev FN, Cunningham K, Schirch V, Safo MK. Ghatge MS, et al. Among authors: schirch v. FEBS Open Bio. 2016 Mar 22;6(5):398-408. doi: 10.1002/2211-5463.12042. eCollection 2016 May. FEBS Open Bio. 2016. PMID: 27419045 Free PMC article.
Crystal structures of human pyridoxal kinase in complex with the neurotoxins, ginkgotoxin and theophylline: insights into pyridoxal kinase inhibition.
Gandhi AK, Desai JV, Ghatge MS, di Salvo ML, Di Biase S, Danso-Danquah R, Musayev FN, Contestabile R, Schirch V, Safo MK. Gandhi AK, et al. Among authors: schirch v. PLoS One. 2012;7(7):e40954. doi: 10.1371/journal.pone.0040954. Epub 2012 Jul 18. PLoS One. 2012. PMID: 22879864 Free PMC article.
Molecular basis of reduced pyridoxine 5'-phosphate oxidase catalytic activity in neonatal epileptic encephalopathy disorder.
Musayev FN, Di Salvo ML, Saavedra MA, Contestabile R, Ghatge MS, Haynes A, Schirch V, Safo MK. Musayev FN, et al. Among authors: schirch v. J Biol Chem. 2009 Nov 6;284(45):30949-56. doi: 10.1074/jbc.M109.038372. Epub 2009 Sep 15. J Biol Chem. 2009. PMID: 19759001 Free PMC article.
Crystal Structure of human pyridoxal kinase: structural basis of M(+) and M(2+) activation.
Musayev FN, di Salvo ML, Ko TP, Gandhi AK, Goswami A, Schirch V, Safo MK. Musayev FN, et al. Among authors: schirch v. Protein Sci. 2007 Oct;16(10):2184-94. doi: 10.1110/ps.073022107. Epub 2007 Aug 31. Protein Sci. 2007. PMID: 17766369 Free PMC article.
Kinetic and structural studies of the role of the active site residue Asp235 of human pyridoxal kinase.
Gandhi AK, Ghatge MS, Musayev FN, Sease A, Aboagye SO, di Salvo ML, Schirch V, Safo MK. Gandhi AK, et al. Among authors: schirch v. Biochem Biophys Res Commun. 2009 Mar 27;381(1):12-5. doi: 10.1016/j.bbrc.2009.01.170. Epub 2009 Feb 4. Biochem Biophys Res Commun. 2009. PMID: 19351586
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