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Page 1
Insights into the molecular pathogenesis of cardiospondylocarpofacial syndrome: MAP3K7 c.737-7A > G variant alters the TGFβ-mediated α-SMA cytoskeleton assembly and autophagy.
Micale L, Morlino S, Biagini T, Carbone A, Fusco C, Ritelli M, Giambra V, Zoppi N, Nardella G, Notarangelo A, Schirizzi A, Mazzoccoli G, Grammatico P, Wade EM, Mazza T, Colombi M, Castori M. Micale L, et al. Among authors: schirizzi a. Biochim Biophys Acta Mol Basis Dis. 2020 Jun 1;1866(6):165742. doi: 10.1016/j.bbadis.2020.165742. Epub 2020 Feb 24. Biochim Biophys Acta Mol Basis Dis. 2020. PMID: 32105826 Free article.
Loss-of-function variants in exon 4 of TAB2 cause a recognizable multisystem disorder with cardiovascular, facial, cutaneous, and musculoskeletal involvement.
Micale L, Morlino S, Carbone A, Carissimo A, Nardella G, Fusco C, Palumbo O, Schirizzi A, Russo F, Mazzoccoli G, Breckpot J, De Luca C, Ferraris A, Giunta C, Grammatico P, Haanpää MK, Mancano G, Forzano G, Cacchiarelli D, Van Esch H, Callewaert B, Rohrbach M, Castori M. Micale L, et al. Among authors: schirizzi a. Genet Med. 2022 Feb;24(2):439-453. doi: 10.1016/j.gim.2021.10.009. Epub 2021 Nov 30. Genet Med. 2022. PMID: 34906501 Free article.
Exon-Trapping Assay Improves Clinical Interpretation of COL11A1 and COL11A2 Intronic Variants in Stickler Syndrome Type 2 and Otospondylomegaepiphyseal Dysplasia.
Micale L, Morlino S, Schirizzi A, Agolini E, Nardella G, Fusco C, Castellana S, Guarnieri V, Villa R, Bedeschi MF, Grammatico P, Novelli A, Castori M. Micale L, et al. Among authors: schirizzi a. Genes (Basel). 2020 Dec 17;11(12):1513. doi: 10.3390/genes11121513. Genes (Basel). 2020. PMID: 33348901 Free PMC article.
VEGFA Status as a Predictive Marker of Therapy Outcome in Metastatic Gastric Cancer Patients Following Ramucirumab-Based Treatment.
Schirizzi A, Arshadi A, Tolomeo D, Schirosi L, Valentini AM, De Leonardis G, Refolo MG, Donghia R, Storlazzi CT, Zito A, Ricci AD, Vallarelli S, Ostuni C, Bencivenga M, De Manzoni G, Messa C, Armentano R, Giannelli G, Lotesoriere C, D'Alessandro R. Schirizzi A, et al. Biomedicines. 2023 Oct 7;11(10):2721. doi: 10.3390/biomedicines11102721. Biomedicines. 2023. PMID: 37893095 Free PMC article.
Development of potent isoflavone-based formyl peptide receptor 1 (FPR1) antagonists and their effects in gastric cancer cell models.
Francavilla F, Sarcina F, Schepetkin IA, Kirpotina LN, Contino M, Schirizzi A, De Leonardis G, Khlebnikov AI, D'Alessandro R, Quinn MT, Lacivita E, Leopoldo M. Francavilla F, et al. Among authors: schirizzi a. Eur J Med Chem. 2023 Dec 5;261:115854. doi: 10.1016/j.ejmech.2023.115854. Epub 2023 Oct 4. Eur J Med Chem. 2023. PMID: 37839346 Free article.
Targeting Angiogenesis in the Era of Biliary Tract Cancer Immunotherapy: Biological Rationale, Clinical Implications, and Future Research Avenues.
Schirizzi A, De Leonardis G, Lorusso V, Donghia R, Rizzo A, Vallarelli S, Ostuni C, Troiani L, Lolli IR, Giannelli G, Ricci AD, D'Alessandro R, Lotesoriere C. Schirizzi A, et al. Cancers (Basel). 2023 Apr 19;15(8):2376. doi: 10.3390/cancers15082376. Cancers (Basel). 2023. PMID: 37190304 Free PMC article. Review.
Corrigendum: Variations in circulating levels of angiopoietin-2 over time are predictive of ramucirumab-paclitaxel therapy outcome in advanced gastric cancer: results of prospective study.
D'Alessandro R, Refolo MG, Schirizzi A, De Leonardis G, Donghia R, Guerra V, Giannelli G, Lolli IR, Laterza MM, De Vita F, Messa C, Lotesoriere C. D'Alessandro R, et al. Among authors: schirizzi a. Front Oncol. 2023 Apr 14;13:1187014. doi: 10.3389/fonc.2023.1187014. eCollection 2023. Front Oncol. 2023. PMID: 37124498 Free PMC article.
Durvalumab in advanced cholangiocarcinoma: is someone knocking down the door?
Ricci AD, D'Alessandro R, Rizzo A, Schirizzi A, Vallarelli S, Ostuni C, Troiani L, Lolli IR, Lotesoriere C, Giannelli G. Ricci AD, et al. Among authors: schirizzi a. Immunotherapy. 2023 May;15(7):477-486. doi: 10.2217/imt-2022-0301. Epub 2023 Mar 23. Immunotherapy. 2023. PMID: 36950960 Review.
The multiple combination of Paclitaxel, Ramucirumab and Elacridar reverses the paclitaxel-mediated resistance in gastric cancer cell lines.
Schirizzi A, Contino M, Carrieri L, Riganti C, De Leonardis G, Scavo MP, Perrone MG, Miciaccia M, Kopecka J, Refolo MG, Lotesoriere C, Depalo N, Rizzi F, Giannelli G, Messa C, D'Alessandro R. Schirizzi A, et al. Front Oncol. 2023 Feb 16;13:1129832. doi: 10.3389/fonc.2023.1129832. eCollection 2023. Front Oncol. 2023. PMID: 36874116 Free PMC article.
Variations in Circulating Levels of Angiopoietin-2 Over Time Are Predictive of Ramucirumab-Paclitaxel Therapy Outcome in Advanced Gastric Cancer: Results of Prospective Study.
D'Alessandro R, Refolo MG, Schirizzi A, De Leonardis G, Donghia R, Guerra V, Giannelli G, Lolli IR, Laterza MM, De Vita F, Messa C, Lotesoriere C. D'Alessandro R, et al. Among authors: schirizzi a. Front Oncol. 2022 Apr 6;12:862116. doi: 10.3389/fonc.2022.862116. eCollection 2022. Front Oncol. 2022. PMID: 35463372 Free PMC article.