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LysM-mediated signaling in Marchantia polymorpha highlights the conservation of pattern-triggered immunity in land plants.
Yotsui I, Matsui H, Miyauchi S, Iwakawa H, Melkonian K, Schlüter T, Michavila S, Kanazawa T, Nomura Y, Stolze SC, Jeon HW, Yan Y, Harzen A, Sugano SS, Shirakawa M, Nishihama R, Ichihashi Y, Ibanez SG, Shirasu K, Ueda T, Kohchi T, Nakagami H. Yotsui I, et al. Among authors: schluter t. Curr Biol. 2023 Sep 11;33(17):3732-3746.e8. doi: 10.1016/j.cub.2023.07.068. Epub 2023 Aug 23. Curr Biol. 2023. PMID: 37619565 Free article.
Optimization and biological evaluation of thiazole-bis-amide inverse agonists of RORγt.
Gege C, Albers M, Kinzel O, Kleymann G, Schlüter T, Steeneck C, Hoffmann T, Xue X, Cummings MD, Spurlino J, Milligan C, Fourie AM, Edwards JP, Leonard K, Coe K, Scott B, Pippel D, Goldberg SD. Gege C, et al. Among authors: schluter t. Bioorg Med Chem Lett. 2020 Jun 15;30(12):127205. doi: 10.1016/j.bmcl.2020.127205. Epub 2020 Apr 21. Bioorg Med Chem Lett. 2020. PMID: 32336498
Discovery and optimization of new oxadiazole substituted thiazole RORγt inverse agonists through a bioisosteric amide replacement approach.
Steeneck C, Gege C, Kinzel O, Albers M, Kleymann G, Schlüter T, Schulz A, Xue X, Cummings MD, Fourie AM, Leonard KA, Scott B, Edwards JP, Hoffmann T, Goldberg SD. Steeneck C, et al. Among authors: schluter t. Bioorg Med Chem Lett. 2020 Jun 15;30(12):127174. doi: 10.1016/j.bmcl.2020.127174. Epub 2020 Apr 7. Bioorg Med Chem Lett. 2020. PMID: 32334912
Regulation of IL-1 signaling by the decoy receptor IL-1R2.
Schlüter T, Schelmbauer C, Karram K, Mufazalov IA. Schlüter T, et al. J Mol Med (Berl). 2018 Oct;96(10):983-992. doi: 10.1007/s00109-018-1684-z. Epub 2018 Aug 15. J Mol Med (Berl). 2018. PMID: 30109367 Review.
Identification and biological evaluation of thiazole-based inverse agonists of RORγt.
Gege C, Cummings MD, Albers M, Kinzel O, Kleymann G, Schlüter T, Steeneck C, Nelen MI, Milligan C, Spurlino J, Xue X, Leonard K, Edwards JP, Fourie A, Goldberg SD, Hoffmann T. Gege C, et al. Among authors: schluter t. Bioorg Med Chem Lett. 2018 May 15;28(9):1446-1455. doi: 10.1016/j.bmcl.2018.03.093. Epub 2018 Apr 3. Bioorg Med Chem Lett. 2018. PMID: 29631962
miR-96 is required for normal development of the auditory hindbrain.
Schlüter T, Berger C, Rosengauer E, Fieth P, Krohs C, Ushakov K, Steel KP, Avraham KB, Hartmann AK, Felmy F, Nothwang HG. Schlüter T, et al. Hum Mol Genet. 2018 Mar 1;27(5):860-874. doi: 10.1093/hmg/ddy007. Hum Mol Genet. 2018. PMID: 29325119
77 results