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Second-generation shRNA libraries covering the mouse and human genomes.
Silva JM, Li MZ, Chang K, Ge W, Golding MC, Rickles RJ, Siolas D, Hu G, Paddison PJ, Schlabach MR, Sheth N, Bradshaw J, Burchard J, Kulkarni A, Cavet G, Sachidanandam R, McCombie WR, Cleary MA, Elledge SJ, Hannon GJ. Silva JM, et al. Among authors: schlabach mr. Nat Genet. 2005 Nov;37(11):1281-8. doi: 10.1038/ng1650. Epub 2005 Oct 2. Nat Genet. 2005. PMID: 16200065
A resource for large-scale RNA-interference-based screens in mammals.
Paddison PJ, Silva JM, Conklin DS, Schlabach M, Li M, Aruleba S, Balija V, O'Shaughnessy A, Gnoj L, Scobie K, Chang K, Westbrook T, Cleary M, Sachidanandam R, McCombie WR, Elledge SJ, Hannon GJ. Paddison PJ, et al. Nature. 2004 Mar 25;428(6981):427-31. doi: 10.1038/nature02370. Nature. 2004. PMID: 15042091
Cancer proliferation gene discovery through functional genomics.
Schlabach MR, Luo J, Solimini NL, Hu G, Xu Q, Li MZ, Zhao Z, Smogorzewska A, Sowa ME, Ang XL, Westbrook TF, Liang AC, Chang K, Hackett JA, Harper JW, Hannon GJ, Elledge SJ. Schlabach MR, et al. Science. 2008 Feb 1;319(5863):620-4. doi: 10.1126/science.1149200. Science. 2008. PMID: 18239126 Free PMC article.
Design of 240,000 orthogonal 25mer DNA barcode probes.
Xu Q, Schlabach MR, Hannon GJ, Elledge SJ. Xu Q, et al. Among authors: schlabach mr. Proc Natl Acad Sci U S A. 2009 Feb 17;106(7):2289-94. doi: 10.1073/pnas.0812506106. Epub 2009 Jan 26. Proc Natl Acad Sci U S A. 2009. PMID: 19171886 Free PMC article.
Synthetic design of strong promoters.
Schlabach MR, Hu JK, Li M, Elledge SJ. Schlabach MR, et al. Proc Natl Acad Sci U S A. 2010 Feb 9;107(6):2538-43. doi: 10.1073/pnas.0914803107. Epub 2010 Jan 21. Proc Natl Acad Sci U S A. 2010. PMID: 20133776 Free PMC article.
A genetic screen for candidate tumor suppressors identifies REST.
Westbrook TF, Martin ES, Schlabach MR, Leng Y, Liang AC, Feng B, Zhao JJ, Roberts TM, Mandel G, Hannon GJ, Depinho RA, Chin L, Elledge SJ. Westbrook TF, et al. Among authors: schlabach mr. Cell. 2005 Jun 17;121(6):837-48. doi: 10.1016/j.cell.2005.03.033. Cell. 2005. PMID: 15960972 Free article.
A SUMOylation-dependent transcriptional subprogram is required for Myc-driven tumorigenesis.
Kessler JD, Kahle KT, Sun T, Meerbrey KL, Schlabach MR, Schmitt EM, Skinner SO, Xu Q, Li MZ, Hartman ZC, Rao M, Yu P, Dominguez-Vidana R, Liang AC, Solimini NL, Bernardi RJ, Yu B, Hsu T, Golding I, Luo J, Osborne CK, Creighton CJ, Hilsenbeck SG, Schiff R, Shaw CA, Elledge SJ, Westbrook TF. Kessler JD, et al. Among authors: schlabach mr. Science. 2012 Jan 20;335(6066):348-53. doi: 10.1126/science.1212728. Epub 2011 Dec 8. Science. 2012. PMID: 22157079 Free PMC article.
31 results