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108 results
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Complex heatmaps reveal patterns and correlations in multidimensional genomic data.
Gu Z, Eils R, Schlesner M. Gu Z, et al. Among authors: schlesner m. Bioinformatics. 2016 Sep 15;32(18):2847-9. doi: 10.1093/bioinformatics/btw313. Epub 2016 May 20. Bioinformatics. 2016. PMID: 27207943
AVAILABILITY AND IMPLEMENTATION: The ComplexHeatmap package and documentation are freely available from the Bioconductor project: http://www.bioconductor.org/packages/devel/bioc/html/ComplexHeatmap.html CONTACT: m.schlesner@dkfz.de SUPPLEMENTARY INFORMATION: Supplem …
AVAILABILITY AND IMPLEMENTATION: The ComplexHeatmap package and documentation are freely available from the Bioconductor project: http://www …
The evolutionary history of 2,658 cancers.
Gerstung M, Jolly C, Leshchiner I, Dentro SC, Gonzalez S, Rosebrock D, Mitchell TJ, Rubanova Y, Anur P, Yu K, Tarabichi M, Deshwar A, Wintersinger J, Kleinheinz K, Vázquez-García I, Haase K, Jerman L, Sengupta S, Macintyre G, Malikic S, Donmez N, Livitz DG, Cmero M, Demeulemeester J, Schumacher S, Fan Y, Yao X, Lee J, Schlesner M, Boutros PC, Bowtell DD, Zhu H, Getz G, Imielinski M, Beroukhim R, Sahinalp SC, Ji Y, Peifer M, Markowetz F, Mustonen V, Yuan K, Wang W, Morris QD; PCAWG Evolution & Heterogeneity Working Group, Spellman PT, Wedge DC, Van Loo P; PCAWG Consortium. Gerstung M, et al. Among authors: schlesner m. Nature. 2020 Feb;578(7793):122-128. doi: 10.1038/s41586-019-1907-7. Epub 2020 Feb 6. Nature. 2020. PMID: 32025013 Free PMC article.
circlize Implements and enhances circular visualization in R.
Gu Z, Gu L, Eils R, Schlesner M, Brors B. Gu Z, et al. Among authors: schlesner m. Bioinformatics. 2014 Oct;30(19):2811-2. doi: 10.1093/bioinformatics/btu393. Epub 2014 Jun 14. Bioinformatics. 2014. PMID: 24930139
gtrellis: an R/Bioconductor package for making genome-level Trellis graphics.
Gu Z, Eils R, Schlesner M. Gu Z, et al. Among authors: schlesner m. BMC Bioinformatics. 2016 Apr 18;17:169. doi: 10.1186/s12859-016-1051-4. BMC Bioinformatics. 2016. PMID: 27089965 Free PMC article.
HilbertCurve: an R/Bioconductor package for high-resolution visualization of genomic data.
Gu Z, Eils R, Schlesner M. Gu Z, et al. Among authors: schlesner m. Bioinformatics. 2016 Aug 1;32(15):2372-4. doi: 10.1093/bioinformatics/btw161. Epub 2016 Mar 24. Bioinformatics. 2016. PMID: 27153599
AVAILABILITY AND IMPLEMENTATION: The HilbertCurve package and documentation are freely available from the Bioconductor project: http://www.bioconductor.org/packages/devel/bioc/html/HilbertCurve.html CONTACT: m.schlesner@dkfz.de SUPPLEMENTARY INFORMATION: Supplementa …
AVAILABILITY AND IMPLEMENTATION: The HilbertCurve package and documentation are freely available from the Bioconductor project: http://www.b …
MYC/MIZ1-dependent gene repression inversely coordinates the circadian clock with cell cycle and proliferation.
Shostak A, Ruppert B, Ha N, Bruns P, Toprak UH; ICGC MMML-Seq Project, Eils R, Schlesner M, Diernfellner A, Brunner M. Shostak A, et al. Among authors: schlesner m. Nat Commun. 2016 Jun 24;7:11807. doi: 10.1038/ncomms11807. Nat Commun. 2016. PMID: 27339797 Free PMC article.
Prenatal maternal stress and wheeze in children: novel insights into epigenetic regulation.
Trump S, Bieg M, Gu Z, Thürmann L, Bauer T, Bauer M, Ishaque N, Röder S, Gu L, Herberth G, Lawerenz C, Borte M, Schlesner M, Plass C, Diessl N, Eszlinger M, Mücke O, Elvers HD, Wissenbach DK, von Bergen M, Herrmann C, Weichenhan D, Wright RJ, Lehmann I, Eils R. Trump S, et al. Among authors: schlesner m. Sci Rep. 2016 Jun 28;6:28616. doi: 10.1038/srep28616. Sci Rep. 2016. PMID: 27349968 Free PMC article. Clinical Trial.
Next-generation personalised medicine for high-risk paediatric cancer patients - The INFORM pilot study.
Worst BC, van Tilburg CM, Balasubramanian GP, Fiesel P, Witt R, Freitag A, Boudalil M, Previti C, Wolf S, Schmidt S, Chotewutmontri S, Bewerunge-Hudler M, Schick M, Schlesner M, Hutter B, Taylor L, Borst T, Sutter C, Bartram CR, Milde T, Pfaff E, Kulozik AE, von Stackelberg A, Meisel R, Borkhardt A, Reinhardt D, Klusmann JH, Fleischhack G, Tippelt S, Dirksen U, Jürgens H, Kramm CM, von Bueren AO, Westermann F, Fischer M, Burkhardt B, Wößmann W, Nathrath M, Bielack SS, Frühwald MC, Fulda S, Klingebiel T, Koscielniak E, Schwab M, Tremmel R, Driever PH, Schulte JH, Brors B, von Deimling A, Lichter P, Eggert A, Capper D, Pfister SM, Jones DT, Witt O. Worst BC, et al. Among authors: schlesner m. Eur J Cancer. 2016 Sep;65:91-101. doi: 10.1016/j.ejca.2016.06.009. Epub 2016 Jul 29. Eur J Cancer. 2016. PMID: 27479119
Identification of immunotherapeutic targets by genomic profiling of rectal NET metastases.
Koşaloğlu Z, Zörnig I, Halama N, Kaiser I, Buchhalter I, Grabe N, Eils R, Schlesner M, Califano A, Jäger D. Koşaloğlu Z, et al. Among authors: schlesner m. Oncoimmunology. 2016 Jul 22;5(11):e1213931. doi: 10.1080/2162402X.2016.1213931. eCollection 2016. Oncoimmunology. 2016. PMID: 27999735 Free PMC article.
Precision oncology based on omics data: The NCT Heidelberg experience.
Horak P, Klink B, Heining C, Gröschel S, Hutter B, Fröhlich M, Uhrig S, Hübschmann D, Schlesner M, Eils R, Richter D, Pfütze K, Geörg C, Meißburger B, Wolf S, Schulz A, Penzel R, Herpel E, Kirchner M, Lier A, Endris V, Singer S, Schirmacher P, Weichert W, Stenzinger A, Schlenk RF, Schröck E, Brors B, von Kalle C, Glimm H, Fröhling S. Horak P, et al. Among authors: schlesner m. Int J Cancer. 2017 Sep 1;141(5):877-886. doi: 10.1002/ijc.30828. Epub 2017 Jun 21. Int J Cancer. 2017. PMID: 28597939
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