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Role of sirtuins in lifespan regulation is linked to methylation of nicotinamide.
Schmeisser K, Mansfeld J, Kuhlow D, Weimer S, Priebe S, Heiland I, Birringer M, Groth M, Segref A, Kanfi Y, Price NL, Schmeisser S, Schuster S, Pfeiffer AF, Guthke R, Platzer M, Hoppe T, Cohen HY, Zarse K, Sinclair DA, Ristow M. Schmeisser K, et al. Among authors: schmeisser s. Nat Chem Biol. 2013 Nov;9(11):693-700. doi: 10.1038/nchembio.1352. Epub 2013 Sep 29. Nat Chem Biol. 2013. PMID: 24077178 Free PMC article.
Extending life span by increasing oxidative stress.
Ristow M, Schmeisser S. Ristow M, et al. Among authors: schmeisser s. Free Radic Biol Med. 2011 Jul 15;51(2):327-36. doi: 10.1016/j.freeradbiomed.2011.05.010. Epub 2011 May 14. Free Radic Biol Med. 2011. PMID: 21619928 Free article. Review.
Mitochondrial hormesis links low-dose arsenite exposure to lifespan extension.
Schmeisser S, Schmeisser K, Weimer S, Groth M, Priebe S, Fazius E, Kuhlow D, Pick D, Einax JW, Guthke R, Platzer M, Zarse K, Ristow M. Schmeisser S, et al. Aging Cell. 2013 Jun;12(3):508-17. doi: 10.1111/acel.12076. Epub 2013 May 6. Aging Cell. 2013. PMID: 23534459 Free PMC article.
Branched-chain amino acid catabolism is a conserved regulator of physiological ageing.
Mansfeld J, Urban N, Priebe S, Groth M, Frahm C, Hartmann N, Gebauer J, Ravichandran M, Dommaschk A, Schmeisser S, Kuhlow D, Monajembashi S, Bremer-Streck S, Hemmerich P, Kiehntopf M, Zamboni N, Englert C, Guthke R, Kaleta C, Platzer M, Sühnel J, Witte OW, Zarse K, Ristow M. Mansfeld J, et al. Among authors: schmeisser s. Nat Commun. 2015 Dec 1;6:10043. doi: 10.1038/ncomms10043. Nat Commun. 2015. PMID: 26620638 Free PMC article.
Mitochondrial DNA copy number and function decrease with age in the short-lived fish Nothobranchius furzeri.
Hartmann N, Reichwald K, Wittig I, Dröse S, Schmeisser S, Lück C, Hahn C, Graf M, Gausmann U, Terzibasi E, Cellerino A, Ristow M, Brandt U, Platzer M, Englert C. Hartmann N, et al. Among authors: schmeisser s. Aging Cell. 2011 Oct;10(5):824-31. doi: 10.1111/j.1474-9726.2011.00723.x. Epub 2011 Jun 27. Aging Cell. 2011. PMID: 21624037 Free article.
21 results