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The Francisella pathogenicity island.
Nano FE, Schmerk C. Nano FE, et al. Ann N Y Acad Sci. 2007 Jun;1105:122-37. doi: 10.1196/annals.1409.000. Epub 2007 Mar 29. Ann N Y Acad Sci. 2007. PMID: 17395722 Review.
The biochemical properties of the Francisella pathogenicity island (FPI)-encoded proteins IglA, IglB, IglC, PdpB and DotU suggest roles in type VI secretion.
de Bruin OM, Duplantis BN, Ludu JS, Hare RF, Nix EB, Schmerk CL, Robb CS, Boraston AB, Hueffer K, Nano FE. de Bruin OM, et al. Among authors: schmerk cl. Microbiology. 2011 Dec;157(Pt 12):3483-3491. doi: 10.1099/mic.0.052308-0. Epub 2011 Oct 6. Microbiology. 2011. PMID: 21980115 Free PMC article.
Essential genes from Arctic bacteria used to construct stable, temperature-sensitive bacterial vaccines.
Duplantis BN, Osusky M, Schmerk CL, Ross DR, Bosio CM, Nano FE. Duplantis BN, et al. Among authors: schmerk cl. Proc Natl Acad Sci U S A. 2010 Jul 27;107(30):13456-60. doi: 10.1073/pnas.1004119107. Epub 2010 Jul 12. Proc Natl Acad Sci U S A. 2010. PMID: 20624965 Free PMC article.
A Francisella novicida pdpA mutant exhibits limited intracellular replication and remains associated with the lysosomal marker LAMP-1.
Schmerk CL, Duplantis BN, Howard PL, Nano FE. Schmerk CL, et al. Microbiology. 2009 May;155(Pt 5):1498-1504. doi: 10.1099/mic.0.025445-0. Epub 2009 Apr 16. Microbiology. 2009. PMID: 19372155 Free PMC article.
The Francisella pathogenicity island protein PdpD is required for full virulence and associates with homologues of the type VI secretion system.
Ludu JS, de Bruin OM, Duplantis BN, Schmerk CL, Chou AY, Elkins KL, Nano FE. Ludu JS, et al. J Bacteriol. 2008 Jul;190(13):4584-95. doi: 10.1128/JB.00198-08. Epub 2008 May 9. J Bacteriol. 2008. PMID: 18469101 Free PMC article.
Characterization of the pathogenicity island protein PdpA and its role in the virulence of Francisella novicida.
Schmerk CL, Duplantis BN, Wang D, Burke RD, Chou AY, Elkins KL, Ludu JS, Nano FE. Schmerk CL, et al. Microbiology. 2009 May;155(Pt 5):1489-1497. doi: 10.1099/mic.0.025379-0. Epub 2009 Apr 16. Microbiology. 2009. PMID: 19372153 Free PMC article.
Generation of protection against Francisella novicida in mice depends on the pathogenicity protein PdpA, but not PdpC or PdpD.
Chou AY, Kennett NJ, Nix EB, Schmerk CL, Nano FE, Elkins KL. Chou AY, et al. Among authors: schmerk cl. Microbes Infect. 2013 Nov;15(12):816-27. doi: 10.1016/j.micinf.2013.07.005. Epub 2013 Jul 20. Microbes Infect. 2013. PMID: 23880085
Elucidation of the Burkholderia cenocepacia hopanoid biosynthesis pathway uncovers functions for conserved proteins in hopanoid-producing bacteria.
Schmerk CL, Welander PV, Hamad MA, Bain KL, Bernards MA, Summons RE, Valvano MA. Schmerk CL, et al. Environ Microbiol. 2015 Mar;17(3):735-50. doi: 10.1111/1462-2920.12509. Epub 2014 Jun 24. Environ Microbiol. 2015. PMID: 24888970
Burkholderia multivorans survival and trafficking within macrophages.
Schmerk CL, Valvano MA. Schmerk CL, et al. J Med Microbiol. 2013 Feb;62(Pt 2):173-184. doi: 10.1099/jmm.0.051243-0. Epub 2012 Oct 25. J Med Microbiol. 2013. PMID: 23105020
The unexpected discovery of a novel low-oxygen-activated locus for the anoxic persistence of Burkholderia cenocepacia.
Sass AM, Schmerk C, Agnoli K, Norville PJ, Eberl L, Valvano MA, Mahenthiralingam E. Sass AM, et al. Among authors: schmerk c. ISME J. 2013 Aug;7(8):1568-81. doi: 10.1038/ismej.2013.36. Epub 2013 Mar 14. ISME J. 2013. PMID: 23486248 Free PMC article.
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