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A prenylated dsRNA sensor protects against severe COVID-19.
Wickenhagen A, Sugrue E, Lytras S, Kuchi S, Noerenberg M, Turnbull ML, Loney C, Herder V, Allan J, Jarmson I, Cameron-Ruiz N, Varjak M, Pinto RM, Lee JY, Iselin L, Palmalux N, Stewart DG, Swingler S, Greenwood EJD, Crozier TWM, Gu Q, Davies EL, Clohisey S, Wang B, Trindade Maranhão Costa F, Freire Santana M, de Lima Ferreira LC, Murphy L, Fawkes A, Meynert A, Grimes G, Da Silva Filho JL, Marti M, Hughes J, Stanton RJ, Wang ECY, Ho A, Davis I, Jarrett RF, Castello A, Robertson DL, Semple MG, Openshaw PJM, Palmarini M, Lehner PJ, Baillie JK, Rihn SJ, Wilson SJ; ISARIC4C Investigators, Baillie JK, Semple MG, Openshaw PJM, Carson G, Alex B, Bach B, Barclay WS, Bogaert D, Chand M, Cooke GS, Docherty AB, Dunning J, da Silva Filipe A, Fletcher T, Green CA, Harrison EM, Ho AYW, Horby PW, Ijaz S, Khoo S, Klenerman P, Law A, Lim WS, Mentzer AJ, Merson L, Meynert AM, Noursadeghi M, Moore SC, Palmarini M, Paxton WA, Pollakis G, Price N, Rambaut A, Robertson DL, Russell CD, Sancho-Shimizu V, Scott JT, de Silva T, Sigfrid L, Solomon T, Sriskandan S, Stuart D, Summers C, Tedder RS, Thomson EC, Thompson AAR, Thwaites RS, Turtle LCW, Gupta RK, Palmieri C, Swann OV, Zambon M, Dumas ME, Griffin JL, Takats Z, Chechi K, Andrikopoulos P, Osagie A, Olanipekun M, Liggi S, Lewis MR, Dos Santos Correia G, Sands CJ, Takis P, Maslen L, Hardwick H, Donohue C, Griffiths F, Oosthuyzen W, Donegan C, Spencer RG, Norman L, Pius R, Drake TM, Fairfield CJ, Knight SR, Mclean KA, Murphy D, Shaw CA, Dalton J, Girvan M, Saviciute E, Roberts S, Harrison J, Marsh L, Connor M, Halpin S, Jackson C, Gamble C, Plotkin D, Lee J, Leeming G, Law A, Wham M, Clohisey S, Hendry R, Scott-Brown J, Greenhalf W, Shaw V, McDonald SE, Keating S, Ahmed KA, Armstrong JA, Ashworth M, Asiimwe IG, Bakshi S, Barlow SL, Booth L, Brennan B, Bullock K, Catterall BWA, Clark JJ, Clarke EA, Cole S, Cooper L, Cox H, Davis C, Dincarslan O, Dunn C, Dyer P, Elliott A, Evans A, Finch L, Fisher LWS, Foster T, Garcia-Dorival I, Greenhalf W, Gunning P, Hartley C, Jensen RL, Jones CB, Jones TR, Khandaker S, King K, Kiy RT, Koukorava C, Lake A, Lant S, Latawiec D, Lavelle-Langham L, Lefteri D, Lett L, Livoti LA, Mancini M, McDonald S, McEvoy L, McLauchlan J, Metelmann S, Miah NS, Middleton J, Mitchell J, Moore SC, Murphy EG, Penrice-Randal R, Pilgrim J, Prince T, Reynolds W, Ridley PM, Sales D, Shaw VE, Shears RK, Small B, Subramaniam KS, Szemiel A, Taggart A, Tanianis-Hughes J, Thomas J, Trochu E, van Tonder L, Wilcock E, Zhang JE, Flaherty L, Maziere N, Cass E, Carracedo AD, Carlucci N, Holmes A, Massey H, Murphy L, Wrobel N, McCafferty S, Morrice K, MacLean A, Adeniji K, Agranoff D, Agwuh K, Ail D, Aldera EL, Alegria A, Allen S, Angus B, Ashish A, Atkinson D, Bari S, Barlow G, Barnass S, Barrett N, Bassford C, Basude S, Baxter D, Beadsworth M, Bernatoniene J, Berridge J, Berry C, Best N, Bothma P, Chadwick D, Brittain-Long R, Bulteel N, Burden T, Burtenshaw A, Caruth V, Chadwick D, Chambler D, Chee N, Child J, Chukkambotla S, Clark T, Collini P, Cosgrove C, Cupitt J, Cutino-Moguel MT, Dark P, Dawson C, Dervisevic S, Donnison P, Douthwaite S, Drummond A, DuRand I, Dushianthan A, Dyer T, Evans C, Eziefula C, Fegan C, Finn A, Fullerton D, Garg S, Garg A, Gkrania-Klotsas E, Godden J, Goldsmith A, Graham C, Hardy E, Hartshorn S, Harvey D, Havalda P, Hawcutt DB, Hobrok M, Hodgson L, Hormis A, Jacobs M, Jain S, Jennings P, Kaliappan A, Kasipandian V, Kegg S, Kelsey M, Kendall J, Kerrison C, Kerslake I, Koch O, Koduri G, Koshy G, Laha S, Laird S, Larkin S, Leiner T, Lillie P, Limb J, Linnett V, Little J, Lyttle M, MacMahon M, MacNaughton E, Mankregod R, Masson H, Matovu E, McCullough K, McEwen R, Meda M, Mills G, Minton J, Mirfenderesky M, Mohandas K, Mok Q, Moon J, Moore E, Morgan P, Morris C, Mortimore K, Moses S, Mpenge M, Mulla R, Murphy M, Nagel M, Nagarajan T, Nelson M, Norris L, O'Shea MK, Otahal I, Ostermann M, Pais M, Palmieri C, Panchatsharam S, Papakonstantinou D, Paraiso H, Patel B, Pattison N, Pepperell J, Peters M, Phull M, Pintus S, Singh Pooni J, Planche T, Post F, Price D, Prout R, Rae N, Reschreiter H, Reynolds T, Richardson N, Roberts M, Roberts D, Rose A, Rousseau G, Ruge B, Ryan B, Saluja T, Schmid ML, Shah A, Shanmuga P, Sharma A, Shawcross A, Sizer J, Shankar-Hari M, Smith R, Snelson C, Spittle N, Staines N, Stambach T, Stewart R, Subudhi P, Szakmany T, Tatham K, Thomas J, Thompson C, Thompson R, Tridente A, Tupper-Carey D, Twagira M, Vallotton N, Vancheeswaran R, Vincent-Smith L, Visuvanathan S, Vuylsteke A, Waddy S, Wake R, Walden A, Welters I, Whitehouse T, Whittaker P, Whittington A, Papineni P, Wijesinghe M, Williams M, Wilson L, Cole S, Winchester S, Wiselka M, Wolverson A, Wootton DG, Workman A, Yates B, Young P. Wickenhagen A, et al. Among authors: schmid ml. Science. 2021 Sep 28:eabj3624. doi: 10.1126/science.abj3624. Online ahead of print. Science. 2021. PMID: 34581622 Free article.
The Aryne-Abramov Reaction as a 1,2-Benzdiyne Platform for the Generation and Solvent-Dependent Trapping of 3-Phosphonyl Benzynes.
Bembenek BM, Petersen MMS, Lilly JA, Haugen AL, Jiter NJ, Johnson AJ, Ripp EE, Winchell SA, Harvat AN, McNulty C, Thein SA, Grieger AM, Lyle BJ, Mraz GL, Stitgen AM, Foss S, Schmid ML, Scanlon JD, Willoughby PH. Bembenek BM, et al. Among authors: schmid ml. J Org Chem. 2021 Aug 6;86(15):10724-10746. doi: 10.1021/acs.joc.1c01382. Epub 2021 Jul 8. J Org Chem. 2021. PMID: 34236859
Co-infection in critically ill patients with COVID-19: an observational cohort study from England.
Baskaran V, Lawrence H, Lansbury LE, Webb K, Safavi S, Zainuddin NI, Huq T, Eggleston C, Ellis J, Thakker C, Charles B, Boyd S, Williams T, Phillips C, Redmore E, Platt S, Hamilton E, Barr A, Venyo L, Wilson P, Bewick T, Daniel P, Dark P, Jeans AR, McCanny J, Edgeworth JD, Llewelyn MJ, Schmid ML, McKeever TM, Beed M, Lim WS. Baskaran V, et al. Among authors: schmid ml. J Med Microbiol. 2021 Apr;70(4):001350. doi: 10.1099/jmm.0.001350. J Med Microbiol. 2021. PMID: 33861190 Free PMC article.
SARS-CoV-2 Testing of 11,884 Healthcare Workers at an Acute NHS Hospital Trust in England: A Retrospective Analysis.
Hanrath AT, Schim van der Loeff I, Lendrem DW, Baker KF, Price DA, McDowall P, McDowall K, Cook S, Towns P, Schwab U, Evans A, Dixon J, Collins J, Burton-Fanning S, Saunders D, Harwood J, Samuel J, Schmid ML, Pareja-Cebrian L, Hunter E, Murphy E, Taha Y, Payne BAI, Duncan CJA. Hanrath AT, et al. Among authors: schmid ml. Front Med (Lausanne). 2021 Mar 12;8:636160. doi: 10.3389/fmed.2021.636160. eCollection 2021. Front Med (Lausanne). 2021. PMID: 33777979 Free PMC article.
COVID-19 Management in a UK NHS Foundation Trust with a High Consequence Infectious Diseases Centre: A Retrospective Analysis.
Baker KF, Hanrath AT, van der Loeff IS, Tee SA, Capstick R, Marchitelli G, Li A, Barr A, Eid A, Ahmed S, Bajwa D, Mohammed O, Alderson N, Lendrem C, Lendrem DW, Covid-Control Group, Covid-Clinical Group, Pareja-Cebrian L, Welch A, Field J, Payne BAI, Taha Y, Price DA, Gibbins C, Schmid ML, Hunter E, Duncan CJA. Baker KF, et al. Among authors: schmid ml. Med Sci (Basel). 2021 Feb 4;9(1):6. doi: 10.3390/medsci9010006. Med Sci (Basel). 2021. PMID: 33557238 Free PMC article.
COVID-19: public health management of the first two confirmed cases identified in the UK.
Holden B, Quinney A, Padfield S, Morton W, Coles S, Manley P, Wensley A, Hutchinson C, Lillie PJ, Duncan CJA, Schmid ML, Li A, Foster K, Anaraki S, Dabrera G, Zambon M, Hughes GJ, Gent M. Holden B, et al. Among authors: schmid ml. Epidemiol Infect. 2020 Aug 28;148:e194. doi: 10.1017/S0950268820001922. Epidemiol Infect. 2020. PMID: 32854791 Free PMC article.
First experience of COVID-19 screening of health-care workers in England.
Hunter E, Price DA, Murphy E, van der Loeff IS, Baker KF, Lendrem D, Lendrem C, Schmid ML, Pareja-Cebrian L, Welch A, Payne BAI, Duncan CJA. Hunter E, et al. Among authors: schmid ml. Lancet. 2020 May 2;395(10234):e77-e78. doi: 10.1016/S0140-6736(20)30970-3. Epub 2020 Apr 22. Lancet. 2020. PMID: 32333843 Free PMC article. No abstract available.
Novel coronavirus disease (Covid-19): The first two patients in the UK with person to person transmission.
Lillie PJ, Samson A, Li A, Adams K, Capstick R, Barlow GD, Easom N, Hamilton E, Moss PJ, Evans A, Ivan M, Phe Incident Team, Taha Y, Duncan CJA, Schmid ML, The Airborne Hcid Network. Lillie PJ, et al. Among authors: schmid ml. J Infect. 2020 May;80(5):578-606. doi: 10.1016/j.jinf.2020.02.020. Epub 2020 Feb 28. J Infect. 2020. PMID: 32119884 Free PMC article. No abstract available.
Human-to-Human Transmission of Monkeypox Virus, United Kingdom, October 2018.
Vaughan A, Aarons E, Astbury J, Brooks T, Chand M, Flegg P, Hardman A, Harper N, Jarvis R, Mawdsley S, McGivern M, Morgan D, Morris G, Nixon G, O'Connor C, Palmer R, Phin N, Price DA, Russell K, Said B, Schmid ML, Vivancos R, Walsh A, Welfare W, Wilburn J, Dunning J. Vaughan A, et al. Among authors: schmid ml. Emerg Infect Dis. 2020 Apr;26(4):782-785. doi: 10.3201/eid2604.191164. Epub 2020 Apr 17. Emerg Infect Dis. 2020. PMID: 32023204 Free PMC article.
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