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SNAC-tag for sequence-specific chemical protein cleavage.
Dang B, Mravic M, Hu H, Schmidt N, Mensa B, DeGrado WF. Dang B, et al. Nat Methods. 2019 Apr;16(4):319-322. doi: 10.1038/s41592-019-0357-3. Epub 2019 Mar 25. Nat Methods. 2019. PMID: 30923372 Free PMC article.
A long-lived Aβ oligomer resistant to fibrillization.
Nick M, Wu Y, Schmidt NW, Prusiner SB, Stöhr J, DeGrado WF. Nick M, et al. Among authors: schmidt nw. Biopolymers. 2018 Aug;109(8):e23096. doi: 10.1002/bip.23096. Epub 2018 Jan 10. Biopolymers. 2018. PMID: 29319162 Free PMC article.
Allosteric cooperation in a de novo-designed two-domain protein.
Pirro F, Schmidt N, Lincoff J, Widel ZX, Polizzi NF, Liu L, Therien MJ, Grabe M, Chino M, Lombardi A, DeGrado WF. Pirro F, et al. Proc Natl Acad Sci U S A. 2020 Dec 29;117(52):33246-33253. doi: 10.1073/pnas.2017062117. Epub 2020 Dec 14. Proc Natl Acad Sci U S A. 2020. PMID: 33318174 Free PMC article.
Designing Hybrid Antibiotic Peptide Conjugates To Cross Bacterial Membranes.
Deshayes S, Xian W, Schmidt NW, Kordbacheh S, Lieng J, Wang J, Zarmer S, Germain SS, Voyen L, Thulin J, Wong GC, Kasko AM. Deshayes S, et al. Among authors: schmidt nw. Bioconjug Chem. 2017 Mar 15;28(3):793-804. doi: 10.1021/acs.bioconjchem.6b00725. Epub 2017 Mar 1. Bioconjug Chem. 2017. PMID: 28248495
Mechanism of a prototypical synthetic membrane-active antimicrobial: Efficient hole-punching via interaction with negative intrinsic curvature lipids.
Yang L, Gordon VD, Trinkle DR, Schmidt NW, Davis MA, DeVries C, Som A, Cronan JE Jr, Tew GN, Wong GC. Yang L, et al. Among authors: schmidt nw. Proc Natl Acad Sci U S A. 2008 Dec 30;105(52):20595-600. doi: 10.1073/pnas.0806456105. Epub 2008 Dec 23. Proc Natl Acad Sci U S A. 2008. PMID: 19106303 Free PMC article.
70 results