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IL-6 trans-signaling is essential for the development of hepatocellular carcinoma in mice.
Bergmann J, Müller M, Baumann N, Reichert M, Heneweer C, Bolik J, Lücke K, Gruber S, Carambia A, Boretius S, Leuschner I, Becker T, Rabe B, Herkel J, Wunderlich FT, Mittrücker HW, Rose-John S, Schmidt-Arras D. Bergmann J, et al. Hepatology. 2017 Jan;65(1):89-103. doi: 10.1002/hep.28874. Epub 2016 Nov 22. Hepatology. 2017. PMID: 27770462
A variant in IL6ST with a selective IL-11 signaling defect in human and mouse.
Schwerd T, Krause F, Twigg SRF, Aschenbrenner D, Chen YH, Borgmeyer U, Müller M, Manrique S, Schumacher N, Wall SA, Jung J, Damm T, Glüer CC, Scheller J, Rose-John S, Jones EY, Laurence A, Wilkie AOM, Schmidt-Arras D, Uhlig HH. Schwerd T, et al. Among authors: schmidt arras d. Bone Res. 2020 Jun 11;8:24. doi: 10.1038/s41413-020-0098-z. eCollection 2020. Bone Res. 2020. PMID: 32566365 Free PMC article.
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