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A phase 1 study of a meningococcal native outer membrane vesicle vaccine made from a group B strain with deleted lpxL1 and synX, over-expressed factor H binding protein, two PorAs and stabilized OpcA expression.
Keiser PB, Biggs-Cicatelli S, Moran EE, Schmiel DH, Pinto VB, Burden RE, Miller LB, Moon JE, Bowden RA, Cummings JF, Zollinger WD. Keiser PB, et al. Among authors: Schmiel DH. Vaccine. 2011 Feb 4;29(7):1413-20. doi: 10.1016/j.vaccine.2010.12.039. Epub 2011 Jan 1. Vaccine. 2011. PMID: 21199704 Clinical Trial.
A phase 1 study of a group B meningococcal native outer membrane vesicle vaccine made from a strain with deleted lpxL2 and synX and stable expression of opcA.
Keiser PB, Gibbs BT, Coster TS, Moran EE, Stoddard MB, Labrie JE 3rd, Schmiel DH, Pinto V, Chen P, Zollinger WD. Keiser PB, et al. Among authors: Schmiel DH. Vaccine. 2010 Oct 8;28(43):6970-6. doi: 10.1016/j.vaccine.2010.08.048. Epub 2010 Aug 21. Vaccine. 2010. PMID: 20732470 Clinical Trial.
Design and evaluation in mice of a broadly protective meningococcal group B native outer membrane vesicle vaccine.
Zollinger WD, Donets MA, Schmiel DH, Pinto VB, Labrie JE 3rd, Moran EE, Brandt BL, Ionin B, Marques R, Wu M, Chen P, Stoddard MB, Keiser PB. Zollinger WD, et al. Among authors: Schmiel DH. Vaccine. 2010 Jul 12;28(31):5057-67. doi: 10.1016/j.vaccine.2010.05.006. Vaccine. 2010. PMID: 20653107
Bacterial phospholipases and pathogenesis.
Schmiel DH, Miller VL. Schmiel DH, et al. Microbes Infect. 1999 Nov;1(13):1103-12. doi: 10.1016/s1286-4579(99)00205-1. Microbes Infect. 1999. PMID: 10572314 Review.
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