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Siglec-H-Deficient Mice Show Enhanced Type I IFN Responses, but Do Not Develop Autoimmunity After Influenza or LCMV Infections.
Szumilas N, Corneth OBJ, Lehmann CHK, Schmitt H, Cunz S, Cullen JG, Chu T, Marosan A, Mócsai A, Benes V, Zehn D, Dudziak D, Hendriks RW, Nitschke L. Szumilas N, et al. Among authors: schmitt h. Front Immunol. 2021 Aug 23;12:698420. doi: 10.3389/fimmu.2021.698420. eCollection 2021. Front Immunol. 2021. PMID: 34497606 Free PMC article.
Absence of Siglec-H in MCMV infection elevates interferon alpha production but does not enhance viral clearance.
Puttur F, Arnold-Schrauf C, Lahl K, Solmaz G, Lindenberg M, Mayer CT, Gohmert M, Swallow M, van Helt C, Schmitt H, Nitschke L, Lambrecht BN, Lang R, Messerle M, Sparwasser T. Puttur F, et al. Among authors: schmitt h. PLoS Pathog. 2013;9(9):e1003648. doi: 10.1371/journal.ppat.1003648. Epub 2013 Sep 26. PLoS Pathog. 2013. PMID: 24086137 Free PMC article.
Siglec-15 on Osteoclasts Is Crucial for Bone Erosion in Serum-Transfer Arthritis.
Korn MA, Schmitt H, Angermüller S, Chambers D, Seeling M, Lux UT, Brey S, Royzman D, Brückner C, Popp V, Percivalle E, Bäuerle T, Zinser E, Winkler TH, Steinkasserer A, Nimmerjahn F, Nitschke L. Korn MA, et al. Among authors: schmitt h. J Immunol. 2020 Nov 15;205(10):2595-2605. doi: 10.4049/jimmunol.2000472. Epub 2020 Oct 5. J Immunol. 2020. PMID: 33020147
Role of the IL23/IL17 Pathway in Crohn's Disease.
Schmitt H, Neurath MF, Atreya R. Schmitt H, et al. Front Immunol. 2021 Mar 30;12:622934. doi: 10.3389/fimmu.2021.622934. eCollection 2021. Front Immunol. 2021. PMID: 33859636 Free PMC article. Review.
Oligonucleotides-A Novel Promising Therapeutic Option for IBD.
Scarozza P, Schmitt H, Monteleone G, Neurath MF, Atreya R. Scarozza P, et al. Among authors: schmitt h. Front Pharmacol. 2019 Apr 24;10:314. doi: 10.3389/fphar.2019.00314. eCollection 2019. Front Pharmacol. 2019. PMID: 31068803 Free PMC article. Review.
The TLR9 Agonist Cobitolimod Induces IL10-Producing Wound Healing Macrophages and Regulatory T Cells in Ulcerative Colitis.
Schmitt H, Ulmschneider J, Billmeier U, Vieth M, Scarozza P, Sonnewald S, Reid S, Atreya I, Rath T, Zundler S, Langheinrich M, Schüttler J, Hartmann A, Winkler T, Admyre C, Knittel T, Dieterich Johansson C, Zargari A, Neurath MF, Atreya R. Schmitt H, et al. J Crohns Colitis. 2020 May 21;14(4):508-524. doi: 10.1093/ecco-jcc/jjz170. J Crohns Colitis. 2020. PMID: 31630153 Free PMC article. Clinical Trial.
Severe Acute Respiratory Syndrome Coronavirus 2 Attachment Receptor Angiotensin-Converting Enzyme 2 Is Decreased in Crohn's Disease and Regulated By Microbial and Inflammatory Signaling.
Patankar JV, Chiriac MT, Lehmann M, Kühl AA, Atreya R, Becker C; Callaborators; Gonzalez-Acera M, Schmitt H, Gamez-Belmonte R, Mahapatro M, Diemand L, Hartmann L, Mascia F, Hracsko Z, Thonn V, Schödel L, Zielinska M, Yu Y, Erkert L, Li W, Zeitler M, Ruder B, Ganzleben I, Günther C, Voehringer D, Zundler S, Neurath MF, Siegmund B. Patankar JV, et al. Among authors: schmitt h. Gastroenterology. 2021 Feb;160(3):925-928.e4. doi: 10.1053/j.gastro.2020.10.021. Epub 2020 Oct 17. Gastroenterology. 2021. PMID: 33075345 Free PMC article. No abstract available.
Resolution of Crohn's disease.
Schmitt H, Neufert C, Neurath MF, Atreya R. Schmitt H, et al. Semin Immunopathol. 2019 Nov;41(6):737-746. doi: 10.1007/s00281-019-00756-1. Epub 2019 Sep 24. Semin Immunopathol. 2019. PMID: 31552470 Review.
Expansion of IL-23 receptor bearing TNFR2+ T cells is associated with molecular resistance to anti-TNF therapy in Crohn's disease.
Schmitt H, Billmeier U, Dieterich W, Rath T, Sonnewald S, Reid S, Hirschmann S, Hildner K, Waldner MJ, Mudter J, Hartmann A, Grützmann R, Neufert C, Münster T, Neurath MF, Atreya R. Schmitt H, et al. Gut. 2019 May;68(5):814-828. doi: 10.1136/gutjnl-2017-315671. Epub 2018 May 30. Gut. 2019. PMID: 29848778 Free PMC article.
1,586 results