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New antibacterial agents derived from the DNA gyrase inhibitor cyclothialidine.
Angehrn P, Buchmann S, Funk C, Goetschi E, Gmuender H, Hebeisen P, Kostrewa D, Link H, Luebbers T, Masciadri R, Nielsen J, Reindl P, Ricklin F, Schmitt-Hoffmann A, Theil FP. Angehrn P, et al. J Med Chem. 2004 Mar 11;47(6):1487-513. doi: 10.1021/jm0310232. J Med Chem. 2004. PMID: 14998336
Investigation of the species-dependent in vitro metabolism of BAL30630 by stable isotope labeling and isotope exchange experiments analyzed by capillary liquid chromatography coupled to mass spectrometry.
Wind M, Grunwald H, Gebhardt K, Illig K, Spickermann J, Nuoffer C, Roussel P, Klauer D, Fullhardt P, Schmitt-Hoffmann A, Schleimer M. Wind M, et al. J Chromatogr A. 2009 May 1;1216(18):3946-53. doi: 10.1016/j.chroma.2009.03.022. Epub 2009 Mar 13. J Chromatogr A. 2009. PMID: 19327777
Experiments for a systematic comparison between stable-isotope-(deuterium) labeling and radio-((14)C) labeling for the elucidation of the in vitro metabolic pattern of pharmaceutical drugs.
Grunwald H, Hargreaves P, Gebhardt K, Klauer D, Serafyn A, Schmitt-Hoffmann A, Schleimer M, Schlotterbeck G, Wind M. Grunwald H, et al. J Pharm Biomed Anal. 2013 Nov;85:138-44. doi: 10.1016/j.jpba.2013.07.004. Epub 2013 Jul 19. J Pharm Biomed Anal. 2013. PMID: 23933567
Elucidation of the in vitro metabolic profile of stable isotope labeled BAL19403 by accurate mass capillary liquid chromatography/quadrupole time-of-flight mass spectrometry and isotope exchange.
Wind M, Gebhardt K, Grunwald H, Spickermann J, Donzelli M, Kellenberger L, Muller M, Fullhardt P, Schmitt-Hoffmann A, Schleimer M. Wind M, et al. Rapid Commun Mass Spectrom. 2007;21(7):1093-9. doi: 10.1002/rcm.2926. Rapid Commun Mass Spectrom. 2007. PMID: 17318924
46 results