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Pilot Preclinical and Clinical Evaluation of (4S)-4-(3-[18F]Fluoropropyl)-L-Glutamate (18F-FSPG) for PET/CT Imaging of Intracranial Malignancies.
Mittra ES, Koglin N, Mosci C, Kumar M, Hoehne A, Keu KV, Iagaru AH, Mueller A, Berndt M, Bullich S, Friebe M, Schmitt-Willich H, Gekeler V, Fels LM, Bacher-Stier C, Moon DH, Chin FT, Stephens AW, Dinkelborg LM, Gambhir SS. Mittra ES, et al. Among authors: schmitt willich h. PLoS One. 2016 Feb 18;11(2):e0148628. doi: 10.1371/journal.pone.0148628. eCollection 2016. PLoS One. 2016. PMID: 26890637 Free PMC article.
Preclinical characterization of a novel class of 18F-labeled PET tracers for amyloid-β.
Brockschnieder D, Schmitt-Willich H, Heinrich T, Varrone A, Gulyás B, Toth M, Andersson J, Boemer U, Krause S, Friebe M, Dinkelborg L, Halldin C, Dyrks T. Brockschnieder D, et al. Among authors: schmitt willich h. J Nucl Med. 2012 Nov;53(11):1794-801. doi: 10.2967/jnumed.112.104810. Epub 2012 Sep 24. J Nucl Med. 2012. PMID: 23008501 Free article.
The Characterization of 18F-hGTS13 for Molecular Imaging of xC- Transporter Activity with PET.
Beinat C, Gowrishankar G, Shen B, Alam IS, Robinson E, Haywood T, Patel CB, Azevedo EC, Castillo JB, Ilovich O, Koglin N, Schmitt-Willich H, Berndt M, Mueller A, Zerna M, Srinivasan A, Gambhir SS. Beinat C, et al. Among authors: schmitt willich h. J Nucl Med. 2019 Dec;60(12):1812-1817. doi: 10.2967/jnumed.119.225870. Epub 2019 Jun 6. J Nucl Med. 2019. PMID: 31171595 Free article.
Discovery and preclinical characterization of [18F]PI-2620, a next-generation tau PET tracer for the assessment of tau pathology in Alzheimer's disease and other tauopathies.
Kroth H, Oden F, Molette J, Schieferstein H, Capotosti F, Mueller A, Berndt M, Schmitt-Willich H, Darmency V, Gabellieri E, Boudou C, Juergens T, Varisco Y, Vokali E, Hickman DT, Tamagnan G, Pfeifer A, Dinkelborg L, Muhs A, Stephens A. Kroth H, et al. Among authors: schmitt willich h. Eur J Nucl Med Mol Imaging. 2019 Sep;46(10):2178-2189. doi: 10.1007/s00259-019-04397-2. Epub 2019 Jul 1. Eur J Nucl Med Mol Imaging. 2019. PMID: 31264169 Free PMC article.
Discovery of 2-(4-(2-fluoroethoxy)piperidin-1-yl)-9-methyl-9H-pyrrolo[2,3-b:4,5-c']dipyridine ([18F]PI-2014) as PET tracer for the detection of pathological aggregated tau in Alzheimer's disease and other tauopathies.
Gabellieri E, Capotosti F, Molette J, Sreenivasachary N, Mueller A, Berndt M, Schieferstein H, Juergens T, Varisco Y, Oden F, Schmitt-Willich H, Hickman D, Dinkelborg L, Stephens A, Pfeifer A, Kroth H. Gabellieri E, et al. Among authors: schmitt willich h. Eur J Med Chem. 2020 Oct 15;204:112615. doi: 10.1016/j.ejmech.2020.112615. Epub 2020 Jul 15. Eur J Med Chem. 2020. PMID: 32771872
PI-2620 Lead Optimization Highlights the Importance of Off-Target Assays to Develop a PET Tracer for the Detection of Pathological Aggregated Tau in Alzheimer's Disease and Other Tauopathies.
Kroth H, Oden F, Molette J, Schieferstein H, Gabellieri E, Mueller A, Berndt M, Sreenivasachary N, Serra AM, Capotosti F, Schmitt-Willich H, Hickman D, Pfeifer A, Dinkelborg L, Stephens A. Kroth H, et al. Among authors: schmitt willich h. J Med Chem. 2021 Sep 9;64(17):12808-12830. doi: 10.1021/acs.jmedchem.1c00861. Epub 2021 Aug 29. J Med Chem. 2021. PMID: 34455780
Preclinical investigation to compare different gadolinium-based contrast agents regarding their propensity to release gadolinium in vivo and to trigger nephrogenic systemic fibrosis-like lesions.
Sieber MA, Lengsfeld P, Frenzel T, Golfier S, Schmitt-Willich H, Siegmund F, Walter J, Weinmann HJ, Pietsch H. Sieber MA, et al. Among authors: schmitt willich h. Eur Radiol. 2008 Oct;18(10):2164-73. doi: 10.1007/s00330-008-0977-y. Epub 2008 Jun 11. Eur Radiol. 2008. PMID: 18545998
27 results