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Filaggrin deficiency confers a paracellular barrier abnormality that reduces inflammatory thresholds to irritants and haptens.
Scharschmidt TC, Man MQ, Hatano Y, Crumrine D, Gunathilake R, Sundberg JP, Silva KA, Mauro TM, Hupe M, Cho S, Wu Y, Celli A, Schmuth M, Feingold KR, Elias PM. Scharschmidt TC, et al. Among authors: schmuth m. J Allergy Clin Immunol. 2009 Sep;124(3):496-506, 506.e1-6. doi: 10.1016/j.jaci.2009.06.046. J Allergy Clin Immunol. 2009. PMID: 19733297 Free PMC article.
Basis for the permeability barrier abnormality in lamellar ichthyosis.
Elias PM, Schmuth M, Uchida Y, Rice RH, Behne M, Crumrine D, Feingold KR, Holleran WM, Pharm D. Elias PM, et al. Among authors: schmuth m. Exp Dermatol. 2002 Jun;11(3):248-56. doi: 10.1034/j.1600-0625.2001.110308.x. Exp Dermatol. 2002. PMID: 12102664
Liver X receptor activators display anti-inflammatory activity in irritant and allergic contact dermatitis models: liver-X-receptor-specific inhibition of inflammation and primary cytokine production.
Fowler AJ, Sheu MY, Schmuth M, Kao J, Fluhr JW, Rhein L, Collins JL, Willson TM, Mangelsdorf DJ, Elias PM, Feingold KR. Fowler AJ, et al. Among authors: schmuth m. J Invest Dermatol. 2003 Feb;120(2):246-55. doi: 10.1046/j.1523-1747.2003.12033.x. J Invest Dermatol. 2003. PMID: 12542530 Free article.
The regulation of permeability barrier homeostasis.
Feingold KR, Schmuth M, Elias PM. Feingold KR, et al. Among authors: schmuth m. J Invest Dermatol. 2007 Jul;127(7):1574-6. doi: 10.1038/sj.jid.5700774. J Invest Dermatol. 2007. PMID: 17568800 Free article.
199 results