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Subunit regulation of the human brain alpha 1E calcium channel.
Parent L, Schneider T, Moore CP, Talwar D. Parent L, et al. J Membr Biol. 1997 Nov 15;160(2):127-40. doi: 10.1007/s002329900302. J Membr Biol. 1997. PMID: 9354705
The alpha1 subunit coding for the human brain type E calcium channel (Schneider et al., 1994) was expressed in Xenopus oocytes in the absence, and in combination with auxiliary alpha2delta and beta subunits. alpha1E channels directed with the expression of Ba2+ whole-cell …
The alpha1 subunit coding for the human brain type E calcium channel (Schneider et al., 1994) was expressed in Xenopus oocytes in the …
Single-channel pharmacology of mibefradil in human native T-type and recombinant Ca(v)3.2 calcium channels.
Michels G, Matthes J, Handrock R, Kuchinke U, Groner F, Cribbs LL, Pereverzev A, Schneider T, Perez-Reyes E, Herzig S. Michels G, et al. Mol Pharmacol. 2002 Mar;61(3):682-94. doi: 10.1124/mol.61.3.682. Mol Pharmacol. 2002. PMID: 11854450
Single recombinant low-voltage-activated T-type calcium channels were studied in comparison, using human embryonic kidney 293 cells overexpressing the pore-forming Ca(v)3.2 subunit. ...In conclusion, the pharmacologic phenotype of these native human T-type channels- …
Single recombinant low-voltage-activated T-type calcium channels were studied in comparison, using human embryonic kidney 293 cells o …
Cloning and expression of a novel member of the low voltage-activated T-type calcium channel family.
Lee JH, Daud AN, Cribbs LL, Lacerda AE, Pereverzev A, Klöckner U, Schneider T, Perez-Reyes E. Lee JH, et al. J Neurosci. 1999 Mar 15;19(6):1912-21. doi: 10.1523/JNEUROSCI.19-06-01912.1999. J Neurosci. 1999. PMID: 10066244 Free PMC article.
We compared these electrophysiological properties to those of the cloned T-type channels alpha1G and alpha1H and to the high voltage-activated channels formed by alpha1Ebeta3. ...Steady-state inactivation occurred at higher potentials than any of the other T channel …
We compared these electrophysiological properties to those of the cloned T-type channels alpha1G and alpha1H and to the high voltage- …
Molecular biology of calcium channels.
Perez-Reyes E, Schneider T. Perez-Reyes E, et al. Kidney Int. 1995 Oct;48(4):1111-24. doi: 10.1038/ki.1995.395. Kidney Int. 1995. PMID: 8569073 Review.
Structural diversity of the voltage-dependent Ca2+ channel alpha1E-subunit.
Pereverzev A, Klöckner U, Henry M, Grabsch H, Vajna R, Olyschläger S, Viatchenko-Karpinski S, Schröder R, Hescheler J, Schneider T. Pereverzev A, et al. Eur J Neurosci. 1998 Mar;10(3):916-25. doi: 10.1046/j.1460-9568.1998.00099.x. Eur J Neurosci. 1998. PMID: 9753159
Actions of sipatrigine, 202W92 and lamotrigine on R-type and T-type Ca2+ channel currents.
Hainsworth AH, McNaughton NC, Pereverzev A, Schneider T, Randall AD. Hainsworth AH, et al. Eur J Pharmacol. 2003 Apr 25;467(1-3):77-80. doi: 10.1016/s0014-2999(03)01625-x. Eur J Pharmacol. 2003. PMID: 12706458
Relatively little has been published on the pharmacology of R-type and T-type Ca(2+) channels. Here, whole-cell Ca(2+) channel currents were recorded from human embryonic kidney 293 cell-lines transfected with either alpha1E subunits (R-type currents) or alpha1G or alpha1I …
Relatively little has been published on the pharmacology of R-type and T-type Ca(2+) channels. Here, whole-cell Ca(2+) channel curren …
Ca2+-sensitive regulation of E-type Ca2+ channel activity depends on an arginine-rich region in the cytosolic II-III loop.
Leroy J, Pereverzev A, Vajna R, Qin N, Pfitzer G, Hescheler J, Malécot CO, Schneider T, Klöckner U. Leroy J, et al. Eur J Neurosci. 2003 Aug;18(4):841-55. doi: 10.1046/j.1460-9568.2003.02819.x. Eur J Neurosci. 2003. PMID: 12925010
Zonisamide block of cloned human T-type voltage-gated calcium channels.
Matar N, Jin W, Wrubel H, Hescheler J, Schneider T, Weiergräber M. Matar N, et al. Epilepsy Res. 2009 Feb;83(2-3):224-34. doi: 10.1016/j.eplepsyres.2008.11.010. Epub 2009 Jan 4. Epilepsy Res. 2009. PMID: 19124225
Zonisamide (ZNS) is a multi-target antiepileptic drug reported to be efficient in the treatment of both partial and generalized seizures, with T-type Ca(2+) channel blockade being one of its proposed mechanisms of action. ...These results suggest that T-type Ca(2+) …
Zonisamide (ZNS) is a multi-target antiepileptic drug reported to be efficient in the treatment of both partial and generalized seizures, wi …
Receptor-mediated modulation of recombinant neuronal class E calcium channels.
Mehrke G, Pereverzev A, Grabsch H, Hescheler J, Schneider T. Mehrke G, et al. FEBS Lett. 1997 May 26;408(3):261-70. doi: 10.1016/s0014-5793(97)00437-7. FEBS Lett. 1997. PMID: 9188773
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