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5-Aza-cytidine is a potent inhibitor of DNA methyltransferase 3a and induces apoptosis in HCT-116 colon cancer cells via Gadd45- and p53-dependent mechanisms.
Schneider-Stock R, Diab-Assef M, Rohrbeck A, Foltzer-Jourdainne C, Boltze C, Hartig R, Schönfeld P, Roessner A, Gali-Muhtasib H. Schneider-Stock R, et al. J Pharmacol Exp Ther. 2005 Feb;312(2):525-36. doi: 10.1124/jpet.104.074195. Epub 2004 Nov 16. J Pharmacol Exp Ther. 2005. PMID: 15547111 Retracted.
Thymoquinone: a promising anti-cancer drug from natural sources.
Gali-Muhtasib H, Roessner A, Schneider-Stock R. Gali-Muhtasib H, et al. Int J Biochem Cell Biol. 2006;38(8):1249-53. doi: 10.1016/j.biocel.2005.10.009. Epub 2005 Nov 8. Int J Biochem Cell Biol. 2006. PMID: 16314136 Review.
Thymoquinone triggers inactivation of the stress response pathway sensor CHEK1 and contributes to apoptosis in colorectal cancer cells.
Gali-Muhtasib H, Kuester D, Mawrin C, Bajbouj K, Diestel A, Ocker M, Habold C, Foltzer-Jourdainne C, Schoenfeld P, Peters B, Diab-Assaf M, Pommrich U, Itani W, Lippert H, Roessner A, Schneider-Stock R. Gali-Muhtasib H, et al. Cancer Res. 2008 Jul 15;68(14):5609-18. doi: 10.1158/0008-5472.CAN-08-0884. Cancer Res. 2008. PMID: 18632613 Free article.
246 results