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On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships.
McAleer CW, Pointon A, Long CJ, Brighton RL, Wilkin BD, Bridges LR, Narasimhan Sriram N, Fabre K, McDougall R, Muse VP, Mettetal JT, Srivastava A, Williams D, Schnepper MT, Roles JL, Shuler ML, Hickman JJ, Ewart L. McAleer CW, et al. Among authors: schnepper mt. Sci Rep. 2019 Jul 3;9(1):9619. doi: 10.1038/s41598-019-45656-4. Sci Rep. 2019. PMID: 31270362 Free PMC article.
Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system.
Oleaga C, Riu A, Rothemund S, Lavado A, McAleer CW, Long CJ, Persaud K, Narasimhan NS, Tran M, Roles J, Carmona-Moran CA, Sasserath T, Elbrecht DH, Kumanchik L, Bridges LR, Martin C, Schnepper MT, Ekman G, Jackson M, Wang YI, Note R, Langer J, Teissier S, Hickman JJ. Oleaga C, et al. Among authors: schnepper mt. Biomaterials. 2018 Nov;182:176-190. doi: 10.1016/j.biomaterials.2018.07.062. Epub 2018 Aug 4. Biomaterials. 2018. PMID: 30130706 Free PMC article.
Long-Term Electrical and Mechanical Function Monitoring of a Human-on-a-Chip System.
Oleaga C, Lavado A, Riu A, Rothemund S, Carmona-Moran CA, Persaud K, Yurko A, Lear J, Narasimhan NS, Long CJ, Sommerhage F, Bridges LR, Cai Y, Martin C, Schnepper MT, Goswami A, Note R, Langer J, Teissier S, Cotovio J, Hickman JJ. Oleaga C, et al. Among authors: schnepper mt. Adv Funct Mater. 2019 Feb 21;29(8):1805792. doi: 10.1002/adfm.201805792. Epub 2018 Dec 14. Adv Funct Mater. 2019. PMID: 35586798 Free PMC article.