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On the potential of in vitro organ-chip models to define temporal pharmacokinetic-pharmacodynamic relationships.
Sci Rep. 2019 Jul 3;9(1):9619. doi: 10.1038/s41598-019-45656-4.
Sci Rep. 2019.
PMID: 31270362
Free PMC article.
Multi-organ system for the evaluation of efficacy and off-target toxicity of anticancer therapeutics.
McAleer CW, Long CJ, Elbrecht D, Sasserath T, Bridges LR, Rumsey JW, Martin C, Schnepper M, Wang Y, Schuler F, Roth AB, Funk C, Shuler ML, Hickman JJ.
McAleer CW, et al.
Sci Transl Med. 2019 Jun 19;11(497):eaav1386. doi: 10.1126/scitranslmed.aav1386.
Sci Transl Med. 2019.
PMID: 31217335
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Inverse liquid-solid chromatography to evaluate drug interactions with organosilane-modified polydimethylsiloxane for use in body-on-a-chip systems.
Schnepper M, Roles J, Hickman JJ.
Schnepper M, et al.
Biotechnol Prog. 2020 Nov;36(6):e3048. doi: 10.1002/btpr.3048. Epub 2020 Aug 18.
Biotechnol Prog. 2020.
PMID: 32663376
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Characterization of Drug-Polymer Adsorption Isotherms in Body-on-a-Chip Systems by Inverse Liquid-Solid Chromatography.
Schnepper MT, Roles J, Hickman JJ.
Schnepper MT, et al.
ACS Biomater Sci Eng. 2020 Aug 10;6(8):4462-4475. doi: 10.1021/acsbiomaterials.0c00350. Epub 2020 Jul 8.
ACS Biomater Sci Eng. 2020.
PMID: 33455187
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Investigation of the effect of hepatic metabolism on off-target cardiotoxicity in a multi-organ human-on-a-chip system.
Oleaga C, Riu A, Rothemund S, Lavado A, McAleer CW, Long CJ, Persaud K, Narasimhan NS, Tran M, Roles J, Carmona-Moran CA, Sasserath T, Elbrecht DH, Kumanchik L, Bridges LR, Martin C, Schnepper MT, Ekman G, Jackson M, Wang YI, Note R, Langer J, Teissier S, Hickman JJ.
Oleaga C, et al. Among authors: schnepper mt.
Biomaterials. 2018 Nov;182:176-190. doi: 10.1016/j.biomaterials.2018.07.062. Epub 2018 Aug 4.
Biomaterials. 2018.
PMID: 30130706
Free PMC article.
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Long-Term Electrical and Mechanical Function Monitoring of a Human-on-a-Chip System.
Oleaga C, Lavado A, Riu A, Rothemund S, Carmona-Moran CA, Persaud K, Yurko A, Lear J, Narasimhan NS, Long CJ, Sommerhage F, Bridges LR, Cai Y, Martin C, Schnepper MT, Goswami A, Note R, Langer J, Teissier S, Cotovio J, Hickman JJ.
Oleaga C, et al. Among authors: schnepper mt.
Adv Funct Mater. 2019 Feb 21;29(8):1805792. doi: 10.1002/adfm.201805792. Epub 2018 Dec 14.
Adv Funct Mater. 2019.
PMID: 35586798
Free PMC article.
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Morphological and functional characterization of human induced pluripotent stem cell-derived neurons (iCell Neurons) in defined culture systems.
Berry BJ, Akanda N, Smith AS, Long CJ, Schnepper MT, Guo X, Hickman JJ.
Berry BJ, et al. Among authors: schnepper mt.
Biotechnol Prog. 2015 Nov-Dec;31(6):1613-22. doi: 10.1002/btpr.2160. Epub 2015 Sep 11.
Biotechnol Prog. 2015.
PMID: 26317319
Free PMC article.
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