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Drug-sensing hydrogels for the inducible release of biopharmaceuticals.
Ehrbar M, Schoenmakers R, Christen EH, Fussenegger M, Weber W. Ehrbar M, et al. Among authors: schoenmakers r. Nat Mater. 2008 Oct;7(10):800-4. doi: 10.1038/nmat2250. Epub 2008 Aug 10. Nat Mater. 2008. PMID: 18690239
Biomolecular hydrogels formed and degraded via site-specific enzymatic reactions.
Ehrbar M, Rizzi SC, Schoenmakers RG, Miguel BS, Hubbell JA, Weber FE, Lutolf MP. Ehrbar M, et al. Among authors: schoenmakers rg. Biomacromolecules. 2007 Oct;8(10):3000-7. doi: 10.1021/bm070228f. Epub 2007 Sep 21. Biomacromolecules. 2007. PMID: 17883273
Poly(ethylene glycol) hydrogels formed by conjugate addition with controllable swelling, degradation, and release of pharmaceutically active proteins.
van de Wetering P, Metters AT, Schoenmakers RG, Hubbell JA. van de Wetering P, et al. Among authors: schoenmakers rg. J Control Release. 2005 Feb 16;102(3):619-27. doi: 10.1016/j.jconrel.2004.10.029. J Control Release. 2005. PMID: 15681084
Enzyme mediated site-specific surface modification.
Sala A, Ehrbar M, Trentin D, Schoenmakers RG, Vörös J, Weber FE. Sala A, et al. Among authors: schoenmakers rg. Langmuir. 2010 Jul 6;26(13):11127-34. doi: 10.1021/la1008895. Langmuir. 2010. PMID: 20545368 Free article.
Engineered Streptomyces quorum-sensing components enable inducible siRNA-mediated translation control in mammalian cells and adjustable transcription control in mice.
Weber W, Malphettes L, de Jesus M, Schoenmakers R, El-Baba MD, Spielmann M, Keller B, Weber CC, van de Wetering P, Aubel D, Wurm FM, Fussenegger M. Weber W, et al. Among authors: schoenmakers r. J Gene Med. 2005 Apr;7(4):518-25. doi: 10.1002/jgm.682. J Gene Med. 2005. PMID: 15521094
6-hydroxy-nicotine-inducible multilevel transgene control in mammalian cells.
Malphettes L, Schoenmakers RG, Fussenegger M. Malphettes L, et al. Among authors: schoenmakers rg. Metab Eng. 2006 Nov;8(6):543-53. doi: 10.1016/j.ymben.2006.07.001. Epub 2006 Jul 22. Metab Eng. 2006. PMID: 16962351
Three-dimensional extracellular matrix-directed cardioprogenitor differentiation: systematic modulation of a synthetic cell-responsive PEG-hydrogel.
Kraehenbuehl TP, Zammaretti P, Van der Vlies AJ, Schoenmakers RG, Lutolf MP, Jaconi ME, Hubbell JA. Kraehenbuehl TP, et al. Among authors: schoenmakers rg. Biomaterials. 2008 Jun;29(18):2757-66. doi: 10.1016/j.biomaterials.2008.03.016. Epub 2008 Apr 7. Biomaterials. 2008. PMID: 18396331
A synthetic mammalian gene circuit reveals antituberculosis compounds.
Weber W, Schoenmakers R, Keller B, Gitzinger M, Grau T, Daoud-El Baba M, Sander P, Fussenegger M. Weber W, et al. Among authors: schoenmakers r. Proc Natl Acad Sci U S A. 2008 Jul 22;105(29):9994-8. doi: 10.1073/pnas.0800663105. Epub 2008 Jul 9. Proc Natl Acad Sci U S A. 2008. PMID: 18621677 Free PMC article.
The effect of the linker on the hydrolysis rate of drug-linked ester bonds.
Schoenmakers RG, van de Wetering P, Elbert DL, Hubbell JA. Schoenmakers RG, et al. J Control Release. 2004 Mar 5;95(2):291-300. doi: 10.1016/j.jconrel.2003.12.009. J Control Release. 2004. PMID: 14980777
Quorum-sensing-based toolbox for regulatable transgene and siRNA expression in mammalian cells.
Weber W, Malphettes L, Rinderknecht M, Schoenmakers RG, Spielmann M, Keller B, van de Wetering P, Weber CC, Fussenegger M. Weber W, et al. Among authors: schoenmakers rg. Biotechnol Prog. 2005 Jan-Feb;21(1):178-85. doi: 10.1021/bp0498995. Biotechnol Prog. 2005. PMID: 15903256
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