Schofield CJ - Search Results

1

X-ray structure of a serine protease acyl-enzyme complex at 0.95-A resolution.

Katona G, Wilmouth RC, Wright PA, Berglund GI, Hajdu J, Neutze R, Schofield CJ. Katona G, et al. Among authors: schofield cj. J Biol Chem. 2002 Jun 14;277(24):21962-70. doi: 10.1074/jbc.M200676200. Epub 2002 Mar 14. J Biol Chem. 2002. PMID: 11896054 Free article.

2

Crystallization and preliminary X-ray diffraction studies on recombinant isopenicillin N synthase from Aspergillus nidulans.

Roach PL, Schofield CJ, Baldwin JE, Clifton IJ, Hajdu J. Roach PL, et al. Among authors: schofield cj. Protein Sci. 1995 May;4(5):1007-9. doi: 10.1002/pro.5560040521. Protein Sci. 1995. PMID: 7663335 Free PMC article.

3

Crystallization and preliminary X-ray diffraction studies on a recombinant isopenicillin N synthase from Cephalosporium acremonium.

Fujishima Y, Nordlund P, Pelosi G, Schofield CJ, Cole SJ, Baldwin JE, Hajdu J. Fujishima Y, et al. Among authors: schofield cj. J Mol Biol. 1994 Oct 7;242(5):712-4. doi: 10.1006/jmbi.1994.1622. J Mol Biol. 1994. PMID: 7932729

4

Anaerobic crystallisation of an isopenicillin N synthase.Fe(II).substrate complex demonstrated by X-ray studies.

Roach PL, Clifton IJ, Hensgens CM, Shibata N, Long AJ, Strange RW, Hasnain SS, Schofield CJ, Baldwin JE, Hajdu J. Roach PL, et al. Among authors: schofield cj. Eur J Biochem. 1996 Dec 15;242(3):736-40. doi: 10.1111/j.1432-1033.1996.0736r.x. Eur J Biochem. 1996. PMID: 9022704 Free article.

5

Structure of a specific acyl-enzyme complex formed between beta-casomorphin-7 and porcine pancreatic elastase.

Wilmouth RC, Clifton IJ, Robinson CV, Roach PL, Aplin RT, Westwood NJ, Hajdu J, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Nat Struct Biol. 1997 Jun;4(6):456-62. doi: 10.1038/nsb0697-456. Nat Struct Biol. 1997. PMID: 9187653

6

Structure of isopenicillin N synthase complexed with substrate and the mechanism of penicillin formation.

Roach PL, Clifton IJ, Hensgens CM, Shibata N, Schofield CJ, Hajdu J, Baldwin JE. Roach PL, et al. Among authors: schofield cj. Nature. 1997 Jun 19;387(6635):827-30. doi: 10.1038/42990. Nature. 1997. PMID: 9194566

7

Structure of a cephalosporin synthase.

Valegård K, van Scheltinga AC, Lloyd MD, Hara T, Ramaswamy S, Perrakis A, Thompson A, Lee HJ, Baldwin JE, Schofield CJ, Hajdu J, Andersson I. Valegård K, et al. Among authors: schofield cj. Nature. 1998 Aug 20;394(6695):805-9. doi: 10.1038/29575. Nature. 1998. PMID: 9723623 Free article.

8

Inhibition of elastase by N-sulfonylaryl beta-lactams: anatomy of a stable acyl-enzyme complex.

Wilmouth RC, Westwood NJ, Anderson K, Brownlee W, Claridge TD, Clifton IJ, Pritchard GJ, Aplin RT, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Biochemistry. 1998 Dec 15;37(50):17506-13. doi: 10.1021/bi9816249. Biochemistry. 1998. PMID: 9860865

9

Studies on the active site of deacetoxycephalosporin C synthase.

Lloyd MD, Lee HJ, Harlos K, Zhang ZH, Baldwin JE, Schofield CJ, Charnock JM, Garner CD, Hara T, Terwisscha van Scheltinga AC, Valegård K, Viklund JA, Hajdu J, Andersson I, Danielsson A, Bhikhabhai R. Lloyd MD, et al. Among authors: schofield cj. J Mol Biol. 1999 Apr 16;287(5):943-60. doi: 10.1006/jmbi.1999.2594. J Mol Biol. 1999. PMID: 10222202 Free article.

10

Mechanistic insights into the inhibition of serine proteases by monocyclic lactams.

Wilmouth RC, Kassamally S, Westwood NJ, Sheppard RJ, Claridge TD, Aplin RT, Wright PA, Pritchard GJ, Schofield CJ. Wilmouth RC, et al. Among authors: schofield cj. Biochemistry. 1999 Jun 22;38(25):7989-98. doi: 10.1021/bi990098y. Biochemistry. 1999. PMID: 10387042

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