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OS-9: another piece in the HIF complex story.
Flashman E, McDonough MA, Schofield CJ. Flashman E, et al. Among authors: schofield cj. Mol Cell. 2005 Feb 18;17(4):472-3. doi: 10.1016/j.molcel.2005.02.001. Mol Cell. 2005. PMID: 15721249 Free article. Review.
Cellular oxygen sensing: Crystal structure of hypoxia-inducible factor prolyl hydroxylase (PHD2).
McDonough MA, Li V, Flashman E, Chowdhury R, Mohr C, Liénard BM, Zondlo J, Oldham NJ, Clifton IJ, Lewis J, McNeill LA, Kurzeja RJ, Hewitson KS, Yang E, Jordan S, Syed RS, Schofield CJ. McDonough MA, et al. Among authors: schofield cj. Proc Natl Acad Sci U S A. 2006 Jun 27;103(26):9814-9. doi: 10.1073/pnas.0601283103. Epub 2006 Jun 16. Proc Natl Acad Sci U S A. 2006. PMID: 16782814 Free PMC article.
The most versatile of all reactive intermediates?
Flashman E, Schofield CJ. Flashman E, et al. Among authors: schofield cj. Nat Chem Biol. 2007 Feb;3(2):86-7. doi: 10.1038/nchembio0207-86. Nat Chem Biol. 2007. PMID: 17235343 No abstract available.
Kinetic rationale for selectivity toward N- and C-terminal oxygen-dependent degradation domain substrates mediated by a loop region of hypoxia-inducible factor prolyl hydroxylases.
Flashman E, Bagg EA, Chowdhury R, Mecinović J, Loenarz C, McDonough MA, Hewitson KS, Schofield CJ. Flashman E, et al. Among authors: schofield cj. J Biol Chem. 2008 Feb 15;283(7):3808-15. doi: 10.1074/jbc.M707411200. Epub 2007 Dec 5. J Biol Chem. 2008. PMID: 18063574 Free article.
Evidence for a stereoelectronic effect in human oxygen sensing.
Loenarz C, Mecinović J, Chowdhury R, McNeill LA, Flashman E, Schofield CJ. Loenarz C, et al. Among authors: schofield cj. Angew Chem Int Ed Engl. 2009;48(10):1784-7. doi: 10.1002/anie.200805427. Angew Chem Int Ed Engl. 2009. PMID: 19180614
705 results