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The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal.
Richard K, Schonhofer C, Giron LB, Rivera-Ortiz J, Read S, Kannan T, Kinloch NN, Shahid A, Feilcke R, Wappler S, Imming P, Harris M, Brumme ZL, Brockman MA, Mounzer K, Kossenkov AV, Abdel-Mohsen M, Andrae-Marobela K, Montaner LJ, Tietjen I. Richard K, et al. Among authors: schonhofer c. J Biol Chem. 2020 Oct 9;295(41):14084-14099. doi: 10.1074/jbc.RA120.013031. Epub 2020 Aug 11. J Biol Chem. 2020. PMID: 32788215 Free PMC article.
Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency.
Schonhofer C, Yi J, Sciorillo A, Andrae-Marobela K, Cochrane A, Harris M, Brumme ZL, Brockman MA, Mounzer K, Hart C, Gyampoh K, Yuan Z, Montaner LJ, Tietjen I. Schonhofer C, et al. Biochem Pharmacol. 2021 Apr;186:114462. doi: 10.1016/j.bcp.2021.114462. Epub 2021 Feb 10. Biochem Pharmacol. 2021. PMID: 33577894 Free PMC article.
The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9.
Tietjen I, Schonhofer C, Sciorillo A, Naidu ME, Haq Z, Kannan T, Kossenkov AV, Rivera-Ortiz J, Mounzer K, Hart C, Gyampoh K, Yuan Z, Beattie KD, Rali T, Shuda McGuire K, Davis RA, Montaner LJ. Tietjen I, et al. Among authors: schonhofer c. Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0160022. doi: 10.1128/aac.01600-22. Epub 2023 Mar 15. Antimicrob Agents Chemother. 2023. PMID: 36975214 Free PMC article.
T-cell activation-induced marker assays in health and disease.
Poloni C, Schonhofer C, Ivison S, Levings MK, Steiner TS, Cook L. Poloni C, et al. Among authors: schonhofer c. Immunol Cell Biol. 2023 Jul;101(6):491-503. doi: 10.1111/imcb.12636. Epub 2023 Mar 21. Immunol Cell Biol. 2023. PMID: 36825901 Free PMC article. Review.