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The African natural product knipholone anthrone and its analogue anthralin (dithranol) enhance HIV-1 latency reversal.
J Biol Chem. 2020 Oct 9;295(41):14084-14099. doi: 10.1074/jbc.RA120.013031. Epub 2020 Aug 11.
J Biol Chem. 2020.
PMID: 32788215
Free PMC article.
Flavonoid-based inhibition of cyclin-dependent kinase 9 without concomitant inhibition of histone deacetylases durably reinforces HIV latency.
Schonhofer C, Yi J, Sciorillo A, Andrae-Marobela K, Cochrane A, Harris M, Brumme ZL, Brockman MA, Mounzer K, Hart C, Gyampoh K, Yuan Z, Montaner LJ, Tietjen I.
Schonhofer C, et al.
Biochem Pharmacol. 2021 Apr;186:114462. doi: 10.1016/j.bcp.2021.114462. Epub 2021 Feb 10.
Biochem Pharmacol. 2021.
PMID: 33577894
Free PMC article.
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Novel Histone Deacetylase Inhibitors and HIV-1 Latency-Reversing Agents Identified by Large-Scale Virtual Screening.
Divsalar DN, Simoben CV, Schonhofer C, Richard K, Sippl W, Ntie-Kang F, Tietjen I.
Divsalar DN, et al. Among authors: schonhofer c.
Front Pharmacol. 2020 Jun 17;11:905. doi: 10.3389/fphar.2020.00905. eCollection 2020.
Front Pharmacol. 2020.
PMID: 32625097
Free PMC article.
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The Aspergillus fumigatus Sialidase (Kdnase) Contributes to Cell Wall Integrity and Virulence in Amphotericin B-Treated Mice.
Nesbitt JR, Steves EY, Schonhofer CR, Cait A, Manku SS, Yeung JHF, Bennet AJ, McNagny KM, Choy JC, Hughes MR, Moore MM.
Nesbitt JR, et al. Among authors: schonhofer cr.
Front Microbiol. 2018 Jan 18;8:2706. doi: 10.3389/fmicb.2017.02706. eCollection 2017.
Front Microbiol. 2018.
PMID: 29403452
Free PMC article.
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The Natural Stilbenoid (-)-Hopeaphenol Inhibits HIV Transcription by Targeting Both PKC and NF-κB Signaling and Cyclin-Dependent Kinase 9.
Tietjen I, Schonhofer C, Sciorillo A, Naidu ME, Haq Z, Kannan T, Kossenkov AV, Rivera-Ortiz J, Mounzer K, Hart C, Gyampoh K, Yuan Z, Beattie KD, Rali T, Shuda McGuire K, Davis RA, Montaner LJ.
Tietjen I, et al. Among authors: schonhofer c.
Antimicrob Agents Chemother. 2023 Apr 18;67(4):e0160022. doi: 10.1128/aac.01600-22. Epub 2023 Mar 15.
Antimicrob Agents Chemother. 2023.
PMID: 36975214
Free PMC article.
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T-cell activation-induced marker assays in health and disease.
Poloni C, Schonhofer C, Ivison S, Levings MK, Steiner TS, Cook L.
Poloni C, et al. Among authors: schonhofer c.
Immunol Cell Biol. 2023 Jul;101(6):491-503. doi: 10.1111/imcb.12636. Epub 2023 Mar 21.
Immunol Cell Biol. 2023.
PMID: 36825901
Free PMC article.
Review.
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