Schoonjans K - Search Results

1

The receptor TGR5 protects the liver from bile acid overload during liver regeneration in mice.

Péan N, Doignon I, Garcin I, Besnard A, Julien B, Liu B, Branchereau S, Spraul A, Guettier C, Humbert L, Schoonjans K, Rainteau D, Tordjmann T. Péan N, et al. Among authors: schoonjans k. Hepatology. 2013 Oct;58(4):1451-60. doi: 10.1002/hep.26463. Epub 2013 Aug 19. Hepatology. 2013. PMID: 23686672

2

Bile acids and the membrane bile acid receptor TGR5--connecting nutrition and metabolism.

Thomas C, Auwerx J, Schoonjans K. Thomas C, et al. Among authors: schoonjans k. Thyroid. 2008 Feb;18(2):167-74. doi: 10.1089/thy.2007.0255. Thyroid. 2008. PMID: 18279017 Review.

3

Novel potent and selective bile acid derivatives as TGR5 agonists: biological screening, structure-activity relationships, and molecular modeling studies.

Sato H, Macchiarulo A, Thomas C, Gioiello A, Une M, Hofmann AF, Saladin R, Schoonjans K, Pellicciari R, Auwerx J. Sato H, et al. Among authors: schoonjans k. J Med Chem. 2008 Mar 27;51(6):1831-41. doi: 10.1021/jm7015864. Epub 2008 Feb 29. J Med Chem. 2008. PMID: 18307294

4

TGR5-mediated bile acid sensing controls glucose homeostasis.

Thomas C, Gioiello A, Noriega L, Strehle A, Oury J, Rizzo G, Macchiarulo A, Yamamoto H, Mataki C, Pruzanski M, Pellicciari R, Auwerx J, Schoonjans K. Thomas C, et al. Among authors: schoonjans k. Cell Metab. 2009 Sep;10(3):167-77. doi: 10.1016/j.cmet.2009.08.001. Cell Metab. 2009. PMID: 19723493 Free PMC article.

5

Raised hepatic bile acid concentrations during pregnancy in mice are associated with reduced farnesoid X receptor function.

Milona A, Owen BM, Cobbold JF, Willemsen EC, Cox IJ, Boudjelal M, Cairns W, Schoonjans K, Taylor-Robinson SD, Klomp LW, Parker MG, White R, van Mil SW, Williamson C. Milona A, et al. Among authors: schoonjans k. Hepatology. 2010 Oct;52(4):1341-9. doi: 10.1002/hep.23849. Hepatology. 2010. PMID: 20842631

6

The bile acid membrane receptor TGR5 as an emerging target in metabolism and inflammation.

Pols TW, Noriega LG, Nomura M, Auwerx J, Schoonjans K. Pols TW, et al. Among authors: schoonjans k. J Hepatol. 2011 Jun;54(6):1263-72. doi: 10.1016/j.jhep.2010.12.004. Epub 2010 Dec 9. J Hepatol. 2011. PMID: 21145931 Free PMC article. Review.

7

Dual farnesoid X receptor/TGR5 agonist INT-767 reduces liver injury in the Mdr2-/- (Abcb4-/-) mouse cholangiopathy model by promoting biliary HCO⁻₃ output.

Baghdasaryan A, Claudel T, Gumhold J, Silbert D, Adorini L, Roda A, Vecchiotti S, Gonzalez FJ, Schoonjans K, Strazzabosco M, Fickert P, Trauner M. Baghdasaryan A, et al. Among authors: schoonjans k. Hepatology. 2011 Oct;54(4):1303-12. doi: 10.1002/hep.24537. Hepatology. 2011. PMID: 22006858 Free PMC article.

8

Bile acids alter male fertility through G-protein-coupled bile acid receptor 1 signaling pathways in mice.

Baptissart M, Vega A, Martinot E, Pommier AJ, Houten SM, Marceau G, de Haze A, Baron S, Schoonjans K, Lobaccaro JM, Volle DH. Baptissart M, et al. Among authors: schoonjans k. Hepatology. 2014 Sep;60(3):1054-65. doi: 10.1002/hep.27204. Hepatology. 2014. PMID: 24798773

9

Small heterodimer partner deletion prevents hepatic steatosis and when combined with farnesoid X receptor loss protects against type 2 diabetes in mice.

Akinrotimi O, Riessen R, VanDuyne P, Park JE, Lee YK, Wong LJ, Zavacki AM, Schoonjans K, Anakk S. Akinrotimi O, et al. Among authors: schoonjans k. Hepatology. 2017 Dec;66(6):1854-1865. doi: 10.1002/hep.29305. Epub 2017 Oct 30. Hepatology. 2017. PMID: 28586124 Free PMC article.

10

Hypothalamic bile acid-TGR5 signaling protects from obesity.

Castellanos-Jankiewicz A, Guzmán-Quevedo O, Fénelon VS, Zizzari P, Quarta C, Bellocchio L, Tailleux A, Charton J, Fernandois D, Henricsson M, Piveteau C, Simon V, Allard C, Quemener S, Guinot V, Hennuyer N, Perino A, Duveau A, Maitre M, Leste-Lasserre T, Clark S, Dupuy N, Cannich A, Gonzales D, Deprez B, Mithieux G, Dombrowicz D, Bäckhed F, Prevot V, Marsicano G, Staels B, Schoonjans K, Cota D. Castellanos-Jankiewicz A, et al. Among authors: schoonjans k. Cell Metab. 2021 Jul 6;33(7):1483-1492.e10. doi: 10.1016/j.cmet.2021.04.009. Epub 2021 Apr 21. Cell Metab. 2021. PMID: 33887197 Free article.

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