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Inflammation, endothelium, and coagulation in sepsis.
Schouten M, Wiersinga WJ, Levi M, van der Poll T. Schouten M, et al. J Leukoc Biol. 2008 Mar;83(3):536-45. doi: 10.1189/jlb.0607373. Epub 2007 Nov 21. J Leukoc Biol. 2008. PMID: 18032692 Review.
Factor V Leiden mutation does not affect coagulopathy or outcome in lethal H1N1 influenza.
Schouten M, van der Sluijs KF, Roelofs JJ, Levi M, Van't Veer C, van der Poll T. Schouten M, et al. Eur Respir J. 2010 Dec;36(6):1346-54. doi: 10.1183/09031936.00204909. Epub 2010 Apr 22. Eur Respir J. 2010. PMID: 20413539
Effect of the factor V Leiden mutation on the incidence and outcome of severe infection and sepsis.
Schouten M, van 't Veer C, van der Poll T, Levi M. Schouten M, et al. Neth J Med. 2012 Sep;70(7):306-10. Neth J Med. 2012. PMID: 22961823 Review.
Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation.
Choi G, Vlaar AP, Schouten M, Van't Veer C, van der Poll T, Levi M, Schultz MJ. Choi G, et al. Among authors: schouten m. Eur Respir J. 2007 Sep;30(3):423-8. doi: 10.1183/09031936.00165606. Epub 2007 May 30. Eur Respir J. 2007. PMID: 17537762
The endothelial protein C receptor and activated protein C play a limited role in host defense during experimental tuberculosis.
Kager LM, Roelofs JJ, de Vos AF, Wieland CW, Schouten M, Meijers JC, Isermann B, Van't Veer C, Esmon CT, van der Poll T. Kager LM, et al. Among authors: schouten m. Thromb Haemost. 2013 Apr;109(4):726-37. doi: 10.1160/TH12-11-0859. Epub 2013 Jan 24. Thromb Haemost. 2013. PMID: 23348224
The cytoprotective effects of endogenous activated protein C reduce activation of coagulation during murine pneumococcal pneumonia and sepsis.
Schouten M, van 't Veer C, Poulussen N, Meijers JC, Levi M, Esmon CT, van der Poll T. Schouten M, et al. Thromb Res. 2015 Mar;135(3):537-43. doi: 10.1016/j.thromres.2014.12.020. Epub 2015 Jan 2. Thromb Res. 2015. PMID: 25586194
The endothelial protein C receptor impairs the antibacterial response in murine pneumococcal pneumonia and sepsis.
Schouten M, de Boer JD, Kager LM, Roelofs JJ, Meijers JC, Esmon CT, Levi M, van 't Veer C, van der Poll T. Schouten M, et al. Thromb Haemost. 2014 May 5;111(5):970-80. doi: 10.1160/TH13-10-0859. Epub 2014 Jan 9. Thromb Haemost. 2014. PMID: 24401906
Overexpression of the endothelial protein C receptor is detrimental during pneumonia-derived gram-negative sepsis (Melioidosis).
Kager LM, Schouten M, Wiersinga WJ, de Boer JD, Lattenist LC, Roelofs JJ, Meijers JC, Levi M, Dondorp AM, Esmon CT, van 't Veer C, van der Poll T. Kager LM, et al. Among authors: schouten m. PLoS Negl Trop Dis. 2013 Jul 11;7(7):e2306. doi: 10.1371/journal.pntd.0002306. Print 2013. PLoS Negl Trop Dis. 2013. PMID: 23875041 Free PMC article.
The lectin-like domain of thrombomodulin hampers host defence in pneumococcal pneumonia.
Schouten M, de Boer JD, van 't Veer C, Roelofs JJ, Meijers JC, Levi M, Conway EM, van der Poll T. Schouten M, et al. Eur Respir J. 2013 Apr;41(4):935-42. doi: 10.1183/09031936.00015212. Epub 2012 Aug 30. Eur Respir J. 2013. PMID: 22936703
Factor v Leiden mutation in severe infection and sepsis.
Levi M, Schouten M, van't Veer C, van der Poll T. Levi M, et al. Among authors: schouten m. Semin Thromb Hemost. 2011 Nov;37(8):955-60. doi: 10.1055/s-0031-1297374. Epub 2011 Dec 23. Semin Thromb Hemost. 2011. PMID: 22198860 Review.
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