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[Diffusion-weighted MRI in patients with Creutzfeldt-Jakob disease].
Kropp S, Finkenstaedt M, Zerr I, Schröter A, Poser S. Kropp S, et al. Nervenarzt. 2000 Feb;71(2):91-5. doi: 10.1007/s001150070001. Nervenarzt. 2000. PMID: 10703009 German.
A new imaging technique called diffusion-weighted MRI (DWI) has recently been established. The sensitivity of DWI was evaluated in five patients suspected of CJD. ...
A new imaging technique called diffusion-weighted MRI (DWI) has recently been established. The sensitivity of DWI was evaluated in fi
Sporadic Creutzfeldt-Jakob disease: magnetic resonance imaging and clinical findings.
Meissner B, Körtner K, Bartl M, Jastrow U, Mollenhauer B, Schröter A, Finkenstaedt M, Windl O, Poser S, Kretzschmar HA, Zerr I. Meissner B, et al. Neurology. 2004 Aug 10;63(3):450-6. doi: 10.1212/01.wnl.0000136225.80445.c9. Neurology. 2004. PMID: 15314808
The MRI was assessed by a blinded investigator for the presence of high signal intensity on T2-weighted images in the basal ganglia. ...Surprisingly, among the CJD cases, patients without signal increase of the basal ganglia were shown to have a higher frequency of …
The MRI was assessed by a blinded investigator for the presence of high signal intensity on T2-weighted images in the basal ganglia. …
CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias.
Schmidt H, Otto M, Niedmann P, Cepek L, Schröter A, Kretzschmar HA, Poser S. Schmidt H, et al. Dement Geriatr Cogn Disord. 2004;17(3):204-6. doi: 10.1159/000076357. Epub 2004 Jan 20. Dement Geriatr Cogn Disord. 2004. PMID: 14739545
LDH isoenzymes were determined in a subset (n = 9). Total LDH and isoenzyme LDH-1 were significantly higher, whereas the fractions of LDH-2 and LDH-3 were significantly lower in CJD patients. We conclude that in addition to established CSF parameters, LDH and its isoenzyme …
LDH isoenzymes were determined in a subset (n = 9). Total LDH and isoenzyme LDH-1 were significantly higher, whereas the fractions of …
Unaltered apoptotic behaviour of mononuclear cells from patients with sporadic Creutzfeldt-Jakob disease.
Ratzka P, Schröter A, Cepek L, Henkel K, Wiltfang J, Kretzschmar HA, Prange H, Poser S, Otto M. Ratzka P, et al. J Neurol. 2001 Aug;248(8):690-4. doi: 10.1007/pl00007834. J Neurol. 2001. PMID: 11569898
In order to determine a possible alteration of MNCs in CJD, we investigated the natural and induced apoptotic behaviour of these cells. ...For the first time, our investigation has demonstrated that a functional impairment of MNCs with regard to their apoptotic beha …
In order to determine a possible alteration of MNCs in CJD, we investigated the natural and induced apoptotic behaviour of these cell …
Patients with Alzheimer's disease and dementia with Lewy bodies mistaken for Creutzfeldt-Jakob disease.
Tschampa HJ, Neumann M, Zerr I, Henkel K, Schröter A, Schulz-Schaeffer WJ, Steinhoff BJ, Kretzschmar HA, Poser S. Tschampa HJ, et al. J Neurol Neurosurg Psychiatry. 2001 Jul;71(1):33-9. doi: 10.1136/jnnp.71.1.33. J Neurol Neurosurg Psychiatry. 2001. PMID: 11413259 Free PMC article.
Their data were compared with a group of patients with CJD (n=25) to determine overlapping and discriminating clinical features. ...
Their data were compared with a group of patients with CJD (n=25) to determine overlapping and discriminating clinical features. ...
Magnetic resonance imaging in the clinical diagnosis of Creutzfeldt-Jakob disease.
Schröter A, Zerr I, Henkel K, Tschampa HJ, Finkenstaedt M, Poser S. Schröter A, et al. Arch Neurol. 2000 Dec;57(12):1751-7. doi: 10.1001/archneur.57.12.1751. Arch Neurol. 2000. PMID: 11115241 Clinical Trial.
BACKGROUND: Creutzfeldt-Jakob disease is a rare neurodegenerative disease that belongs to the group of human spongiform encephalopathies and usually affects elderly people. ...This corresponds to a high specificity in the differential diagnosis of CJD. CONCLUSION: T …
BACKGROUND: Creutzfeldt-Jakob disease is a rare neurodegenerative disease that belongs to the group of human spongiform encephalopath …
Current clinical diagnosis in Creutzfeldt-Jakob disease: identification of uncommon variants.
Zerr I, Schulz-Schaeffer WJ, Giese A, Bodemer M, Schröter A, Henkel K, Tschampa HJ, Windl O, Pfahlberg A, Steinhoff BJ, Gefeller O, Kretzschmar HA, Poser S. Zerr I, et al. Ann Neurol. 2000 Sep;48(3):323-9. Ann Neurol. 2000. PMID: 10976638
Valine-homozygous patients had a negative EEG, but most had detectable levels of neuronal proteins in the CSF. The sensitivity of the magnetic resonance imaging was 70%, irrespective of the subgroup, but was particularly reliable in the clinical diagnosis of MV2 patients. …
Valine-homozygous patients had a negative EEG, but most had detectable levels of neuronal proteins in the CSF. The sensitivity of the …
Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Otto M, Esselmann H, Schulz-Shaeffer W, Neumann M, Schröter A, Ratzka P, Cepek L, Zerr I, Steinacker P, Windl O, Kornhuber J, Kretzschmar HA, Poser S, Wiltfang J. Otto M, et al. Neurology. 2000 Mar 14;54(5):1099-102. doi: 10.1212/wnl.54.5.1099. Neurology. 2000. PMID: 10720281
All the neuropathologically verified patients presented with a type 1 prion protein pattern. CJD patients were all homozygous for methionine at codon 129. ...CONCLUSION: Low levels of Abeta1-42 in CSF do not exclude a diagnosis of CJD. Decreased levels of Abeta1-42 …
All the neuropathologically verified patients presented with a type 1 prion protein pattern. CJD patients were all homozygous for met …
The effect of stress on the onset and progression of Creutzfeldt-Jakob disease: results of a German pilot case-control study.
Laske C, Gefeller O, Pfahlberg A, Zerr I, Schröter A, Poser S. Laske C, et al. Eur J Epidemiol. 1999 Aug;15(7):631-5. doi: 10.1023/a:1007683208121. Eur J Epidemiol. 1999. PMID: 10543352
The association between Creutzfeldt-Jakob disease (CJD) and stressful life events was examined in a pilot case-control study in Germany. ...Although based on a rather small study sample, this pilot case-control investigation suggests evidence that stressful life eve …
The association between Creutzfeldt-Jakob disease (CJD) and stressful life events was examined in a pilot case-control study in Germa …
Different binding pattern of antibodies to prion protein on lymphocytes from patients with sporadic Creutzfeldt-Jakob disease.
Ratzka P, Döhlinger S, Cepek L, Steinacker P, Arlt S, Jacobi C, Schröter A, Wiltfang J, Prange H, Kretzschmar HA, Poser S, Otto M. Ratzka P, et al. Neurosci Lett. 2003 May 29;343(1):29-32. doi: 10.1016/s0304-3940(03)00315-x. Neurosci Lett. 2003. PMID: 12749990
In Creutzfeldt-Jakob disease (CJD), progressive neuronal cell death probably occurs as a result of a change in conformation of the physiological prion protein (PrP(C)). ...Using fluorescence cytometry, we investigated a possible alteration of PrP(C) on lympho …
In Creutzfeldt-Jakob disease (CJD), progressive neuronal cell death probably occurs as a result of a change in conformation of …
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