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Cytoprotective effects of CI-959 in the rat gastric mucosa: modulation of leukocyte adhesion.
Low J, Grabow D, Sommers C, Wallace J, Lesch M, Finkel M, Schrier D, Metz A, Conroy MC. Low J, et al. Gastroenterology. 1995 Oct;109(4):1224-33. doi: 10.1016/0016-5085(95)90582-0. Gastroenterology. 1995. PMID: 7557089
Anti-inflammatory properties of the protein kinase C inhibitor, 3-[1-[3-(dimethylamino)propyl]-1H-indol-3-yl]-4-(1H-indol-3-yl)-1H- pyrrole-2,5-dione monohydrochloride (GF109203X) in the PMA-mouse ear edema model.
Kuchera S, Barth H, Jacobson P, Metz A, Schaechtele C, Schrier D. Kuchera S, et al. Agents Actions. 1993;39 Spec No:C169-73. doi: 10.1007/BF01972756. Agents Actions. 1993. PMID: 8273558
Anti-inflammatory properties of Gö 6850: a selective inhibitor of protein kinase C.
Jacobson PB, Kuchera SL, Metz A, Schächtele C, Imre K, Schrier DJ. Jacobson PB, et al. J Pharmacol Exp Ther. 1995 Nov;275(2):995-1002. J Pharmacol Exp Ther. 1995. PMID: 7473193
1,3,4-Oxadiazole, 1,3,4-thiadiazole, and 1,2,4-triazole analogs of the fenamates: in vitro inhibition of cyclooxygenase and 5-lipoxygenase activities.
Boschelli DH, Connor DT, Bornemeier DA, Dyer RD, Kennedy JA, Kuipers PJ, Okonkwo GC, Schrier DJ, Wright CD. Boschelli DH, et al. J Med Chem. 1993 Jun 25;36(13):1802-10. doi: 10.1021/jm00065a002. J Med Chem. 1993. PMID: 8515419
Design of 5-(3,5-di-tert-butyl-4-hydroxyphenyl)-1,3,4-thiadiazoles, -1,3,4-oxadiazoles, and -1,2,4-triazoles as orally-active, nonulcerogenic antiinflammatory agents.
Mullican MD, Wilson MW, Connor DT, Kostlan CR, Schrier DJ, Dyer RD. Mullican MD, et al. J Med Chem. 1993 Apr 16;36(8):1090-9. doi: 10.1021/jm00060a017. J Med Chem. 1993. PMID: 8478906
The pharmacologic effects of 5-[3,5-bis(1,1-dimethylethyl)-4- hydroxyphenyl]-1,3,4-thiadiazole-2(3H)-thione, choline salt (CI-986), a novel inhibitor of arachidonic acid metabolism in models of inflammation, analgesia and gastric irritation.
Schrier DJ, Baragi VM, Connor DT, Dyer RD, Jordan JH, Imre KM, Lesch ME, Mullican MD, Okonkwo GC, Conroy MC. Schrier DJ, et al. Prostaglandins. 1994 Jan;47(1):17-30. doi: 10.1016/0090-6980(94)90071-x. Prostaglandins. 1994. PMID: 8140259
The in vivo antiinflammatory effects of (E)-2,6-bis(1,1-dimethyl-ethyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethenyl ] phenol (PD 127443) a novel dual inhibitor of 5-lipoxygenase and cyclooxygenase.
Schrier DJ, Adamchak MA, Boctor AM, Kostlan CR, Flynn DL, Jordan JH Jr, Lesch ME, Okonkwo GC. Schrier DJ, et al. Agents Actions. 1989 Jun;27(3-4):391-4. doi: 10.1007/BF01972831. Agents Actions. 1989. PMID: 2552768 No abstract available.
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