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Caspase-1 self-cleavage is an intrinsic mechanism to terminate inflammasome activity.
Boucher D, Monteleone M, Coll RC, Chen KW, Ross CM, Teo JL, Gomez GA, Holley CL, Bierschenk D, Stacey KJ, Yap AS, Bezbradica JS, Schroder K. Boucher D, et al. Among authors: schroder k. J Exp Med. 2018 Mar 5;215(3):827-840. doi: 10.1084/jem.20172222. Epub 2018 Feb 6. J Exp Med. 2018. PMID: 29432122 Free PMC article.
Neutrophil Extracellular Traps in Host Defense.
Burgener SS, Schroder K. Burgener SS, et al. Among authors: schroder k. Cold Spring Harb Perspect Biol. 2020 Jul 1;12(7):a037028. doi: 10.1101/cshperspect.a037028. Cold Spring Harb Perspect Biol. 2020. PMID: 31767647 Review.
Vincristine-induced peripheral neuropathy is driven by canonical NLRP3 activation and IL-1β release.
Starobova H, Monteleone M, Adolphe C, Batoon L, Sandrock CJ, Tay B, Deuis JR, Smith AV, Mueller A, Nadar EI, Lawrence GP, Mayor A, Tolson E, Levesque JP, Pettit AR, Wainwright BJ, Schroder K, Vetter I. Starobova H, et al. Among authors: schroder k. J Exp Med. 2021 May 3;218(5):e20201452. doi: 10.1084/jem.20201452. J Exp Med. 2021. PMID: 33656514 Free PMC article.
A small-molecule inhibitor of the NLRP3 inflammasome for the treatment of inflammatory diseases.
Coll RC, Robertson AA, Chae JJ, Higgins SC, Muñoz-Planillo R, Inserra MC, Vetter I, Dungan LS, Monks BG, Stutz A, Croker DE, Butler MS, Haneklaus M, Sutton CE, Núñez G, Latz E, Kastner DL, Mills KH, Masters SL, Schroder K, Cooper MA, O'Neill LA. Coll RC, et al. Among authors: schroder k. Nat Med. 2015 Mar;21(3):248-55. doi: 10.1038/nm.3806. Epub 2015 Feb 16. Nat Med. 2015. PMID: 25686105 Free PMC article.
782 results