Schubert DR - Search Results

1

Promoting basal levels of autophagy in the nervous system enhances longevity and oxidant resistance in adult Drosophila.

Simonsen A, Cumming RC, Brech A, Isakson P, Schubert DR, Finley KD. Simonsen A, et al. Among authors: schubert dr. Autophagy. 2008 Feb;4(2):176-84. doi: 10.4161/auto.5269. Epub 2007 Nov 6. Autophagy. 2008. PMID: 18059160

2

p62, Ref(2)P and ubiquitinated proteins are conserved markers of neuronal aging, aggregate formation and progressive autophagic defects.

Bartlett BJ, Isakson P, Lewerenz J, Sanchez H, Kotzebue RW, Cumming RC, Harris GL, Nezis IP, Schubert DR, Simonsen A, Finley KD. Bartlett BJ, et al. Among authors: schubert dr. Autophagy. 2011 Jun;7(6):572-83. doi: 10.4161/auto.7.6.14943. Epub 2011 Jun 1. Autophagy. 2011. PMID: 21325881 Free PMC article.

3

Amyloid-beta induces disulfide bonding and aggregation of GAPDH in Alzheimer's disease.

Cumming RC, Schubert D. Cumming RC, et al. FASEB J. 2005 Dec;19(14):2060-2. doi: 10.1096/fj.05-4195fje. Epub 2005 Sep 26. FASEB J. 2005. PMID: 16186172

4

Increase in expression levels and resistance to sulfhydryl oxidation of peroxiredoxin isoforms in amyloid beta-resistant nerve cells.

Cumming RC, Dargusch R, Fischer WH, Schubert D. Cumming RC, et al. J Biol Chem. 2007 Oct 19;282(42):30523-34. doi: 10.1074/jbc.M700869200. Epub 2007 Aug 29. J Biol Chem. 2007. PMID: 17761673 Free article.

5

Neural cells secrete a unique repertoire of proteins.

Schubert D, Herrera F, Cumming R, Read J, Low W, Maher P, Fischer WH. Schubert D, et al. J Neurochem. 2009 Apr;109(2):427-35. doi: 10.1111/j.1471-4159.2009.05968.x. Epub 2009 Feb 7. J Neurochem. 2009. PMID: 19200335 Free PMC article.

6

Protein disulfide bond formation in the cytoplasm during oxidative stress.

Cumming RC, Andon NL, Haynes PA, Park M, Fischer WH, Schubert D. Cumming RC, et al. J Biol Chem. 2004 May 21;279(21):21749-58. doi: 10.1074/jbc.M312267200. Epub 2004 Mar 18. J Biol Chem. 2004. PMID: 15031298 Free article.

7

The mitochondrial ATP synthase is a shared drug target for aging and dementia.

Goldberg J, Currais A, Prior M, Fischer W, Chiruta C, Ratliff E, Daugherty D, Dargusch R, Finley K, Esparza-Moltó PB, Cuezva JM, Maher P, Petrascheck M, Schubert D. Goldberg J, et al. Aging Cell. 2018 Apr;17(2):e12715. doi: 10.1111/acel.12715. Epub 2018 Jan 7. Aging Cell. 2018. PMID: 29316249 Free PMC article.

8

Geroprotective effects of Alzheimer's disease drug candidates.

Kepchia D, Currais A, Dargusch R, Finley K, Schubert D, Maher P. Kepchia D, et al. Aging (Albany NY). 2021 Feb 6;13(3):3269-3289. doi: 10.18632/aging.202631. Epub 2021 Feb 6. Aging (Albany NY). 2021. PMID: 33550278 Free PMC article.

9

The regulation of glucose metabolism by HIF-1 mediates a neuroprotective response to amyloid beta peptide.

Soucek T, Cumming R, Dargusch R, Maher P, Schubert D. Soucek T, et al. Neuron. 2003 Jul 3;39(1):43-56. doi: 10.1016/s0896-6273(03)00367-2. Neuron. 2003. PMID: 12848931 Free article.

10

Geroneuroprotectors: Effective Geroprotectors for the Brain.

Schubert D, Currais A, Goldberg J, Finley K, Petrascheck M, Maher P. Schubert D, et al. Trends Pharmacol Sci. 2018 Dec;39(12):1004-1007. doi: 10.1016/j.tips.2018.09.008. Epub 2018 Nov 13. Trends Pharmacol Sci. 2018. PMID: 30446211 Free PMC article. Review.

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