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Virucidal effect of peppermint oil on the enveloped viruses herpes simplex virus type 1 and type 2 in vitro.
Schuhmacher A, Reichling J, Schnitzler P. Schuhmacher A, et al. Phytomedicine. 2003;10(6-7):504-10. doi: 10.1078/094471103322331467. Phytomedicine. 2003. PMID: 13678235
The inhibitory activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) was tested in vitro on RC-37 cells using a plaque reduction assay. ...A clearly time-dependent activity could be demonstrated, after 3 h of incubation of herp …
The inhibitory activity against herpes simplex virus type 1 (HSV-1) and herpes simplex virus type 2 (HSV-2) was tested in vitro on RC-37 cel …
Melissa officinalis oil affects infectivity of enveloped herpesviruses.
Schnitzler P, Schuhmacher A, Astani A, Reichling J. Schnitzler P, et al. Among authors: schuhmacher a. Phytomedicine. 2008 Sep;15(9):734-40. doi: 10.1016/j.phymed.2008.04.018. Phytomedicine. 2008. PMID: 18693101
Melissa officinalis essential oil was phytochemically examined by GC-MS analysis, its main constituents were identified as monoterpenaldehydes citral a, citral b and citronellal. ...The inhibitory activity against herpes simplex virus type 1 (HSV-1)and herpes simplex virus …
Melissa officinalis essential oil was phytochemically examined by GC-MS analysis, its main constituents were identified as monoterpenaldehyd …
Tiamulin and semduramicin: effects of simultaneous administration on performance and health of growing broiler chickens.
Schuhmacher A, Bafundo KW, Islam KM, Aupperle H, Glaser R, Schoon HA, Gropp JM. Schuhmacher A, et al. Poult Sci. 2006 Mar;85(3):441-5. doi: 10.1093/ps/85.3.441. Poult Sci. 2006. PMID: 16553273 Clinical Trial.
The pleuromutilin antibiotic tiamulin (TIA) is known to produce a variety of negative interactive effects when it is administered in combination with several anticoccidial ionophores. ...Tiamulin and SEM, both alone and in combination, were administered to 10 replicates of …
The pleuromutilin antibiotic tiamulin (TIA) is known to produce a variety of negative interactive effects when it is administered in …
Regenerative capacity differs between micro- and macrovesicular hepatic steatosis.
Oleszczuk A, Spannbauer M, Tannapfel A, Blüher M, Hengstler J, Pietsch UC, Schuhmacher A, Wittekind C, Hauss JP, Schön MR. Oleszczuk A, et al. Among authors: schuhmacher a. Exp Toxicol Pathol. 2007 Nov;59(3-4):205-13. doi: 10.1016/j.etp.2007.05.009. Epub 2007 Sep 14. Exp Toxicol Pathol. 2007. PMID: 17869075
INTRODUCTION: Independent of etiology, the hepatic microvesicular steatosis has a worse prognosis compared with macrovesicular steatosis. ...METHODS: Two groups of pigs were studied for 72 days under a protein-deficient diet. One group received only protein-deficien …
INTRODUCTION: Independent of etiology, the hepatic microvesicular steatosis has a worse prognosis compared with macrovesicular steato …
Micro- and macrovesicular steatotic liver model for transplantation induced by ethanol and protein-deficient diet.
Spannbauer MM, Oleszczuk A, Tannapfel A, Blüher M, Pietsch UC, Hengstler J, Donaubauer B, Madaj-Sterba P, Fürll M, Schuhmacher A, Thiery J, Hauss JP, Schön MR. Spannbauer MM, et al. Among authors: schuhmacher a. Transplant Proc. 2005 Jan-Feb;37(1):210-1. doi: 10.1016/j.transproceed.2004.12.136. Transplant Proc. 2005. PMID: 15808596
For a lack of a reliable fatty liver model, preservation concepts for fatty livers have hardly been evaluated. Moreover, there is an ongoing debate on the relevance and impact of micro- versus macrovesicular steatotic organs. ...For the first time, we established …
For a lack of a reliable fatty liver model, preservation concepts for fatty livers have hardly been evaluated. Moreover, there …
Selective absorption of carotenoids in the common green iguana (Iguana iguana).
Raila J, Schuhmacher A, Gropp J, Schweigert FJ. Raila J, et al. Among authors: schuhmacher a. Comp Biochem Physiol A Mol Integr Physiol. 2002 Jun;132(2):513-8. doi: 10.1016/s1095-6433(02)00098-3. Comp Biochem Physiol A Mol Integr Physiol. 2002. PMID: 12020667
To investigate the absorption of selected carotenoids, 20 juvenile green iguanas (Iguana iguana) were fed a carotenoid deficient basal diet for 56 days. ...The iguana might, therefore, be a valuable model to investigate the selectiveness of carotenoid absorption as …
To investigate the absorption of selected carotenoids, 20 juvenile green iguanas (Iguana iguana) were fed a carotenoid deficient basa …
Effect of dietary beta-carotene on the accumulation of beta-carotene and vitamin A in plasma and tissues of gilts.
Schweigert FJ, Buchholz I, Schuhmacher A, Gropp J. Schweigert FJ, et al. Among authors: schuhmacher a. Reprod Nutr Dev. 2001 Jan-Feb;41(1):47-55. doi: 10.1051/rnd:2001111. Reprod Nutr Dev. 2001. PMID: 11368244

Liver levels of vitamin A were higher (P < 0.01) at comparable levels in the VA + VA and VA + BC group than in the VA group, indicating a conversion rate of beta-carotene to vitamin A of 40 to 1 on the basis of weight for beta-carotene at this level (100 m

Liver levels of vitamin A were higher (P < 0.01) at comparable levels in the VA + VA and VA + BC group than in the VA group, indic

The upside of being a digital pharma player.
Schuhmacher A, Gatto A, Hinder M, Kuss M, Gassmann O. Schuhmacher A, et al. Drug Discov Today. 2020 Jun 15:S1359-6446(20)30227-0. doi: 10.1016/j.drudis.2020.06.002. Online ahead of print. Drug Discov Today. 2020. PMID: 32554063
The impact of crowdsourcing in modern drug discovery.
Schuhmacher A, Kuss M. Schuhmacher A, et al. Expert Opin Drug Discov. 2020 Aug;15(8):865-867. doi: 10.1080/17460441.2020.1751116. Epub 2020 Apr 7. Expert Opin Drug Discov. 2020. PMID: 32255703 No abstract available.
Correction: Glioblastoma and glioblastoma stem cells are dependent on functional MTH1.
Pudelko L, Rouhi P, Sanjiv K, Gad H, Kalderén C, Höglund A, Squatrito M, Schuhmacher AJ, Edwards S, Hägerstrand D, Berglund UW, Helleday T, Bräutigam L. Pudelko L, et al. Among authors: schuhmacher aj. Oncotarget. 2020 Feb 25;11(8):827. doi: 10.18632/oncotarget.27484. eCollection 2020 Feb 25. Oncotarget. 2020. PMID: 32166004 Free PMC article.
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